A5101603965- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- BRCA gene mutations in cancer
- Metabolism and Genetic Disorders
- HIV Research and Treatment
- Viral gastroenteritis research and epidemiology
- Biosensors and Analytical Detection
- Prenatal Screening and Diagnostics
- Osteoarthritis Treatment and Mechanisms
- Heme Oxygenase-1 and Carbon Monoxide
- Neurological and metabolic disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Ethics in Clinical Research
- HIV/AIDS drug development and treatment
University of British Columbia
2024
The University of Sydney
2024
Northern Sydney Local Health District
2024
Guy's and St Thomas' NHS Foundation Trust
2021
St Thomas' Hospital
2021
Public Health England
2016
SummaryBackgroundLateral flow devices (LFDs) for rapid antigen testing are set to become a cornerstone of SARS-CoV-2 mass community testing, although their reduced sensitivity compared with PCR has raised questions how well they identify infectious cases. Understanding capabilities and limitations is, therefore, essential successful implementation. We evaluated six commercial LFDs assessed correlation virus culture cycle threshold (Ct) values.MethodsIn single-centre, laboratory evaluation...
To determine the prevalence of inferred low-frequency HIV-1 transmitted drug resistance (TDR) in MSM UK and its predicted effect on first-line therapy.The pol gene was amplified from 442 newly diagnosed identified as likely recently infected by serological avidity testing 2011-13. The PCR products were sequenced next-generation sequencing with a mutation frequency threshold >2% TDR mutations defined according to 2009 WHO surveillance list.The majority (75.6%) subtype B 6.6% rare complex or...
Abstract Non‐paternity (NP) is a challenging dilemma faced by genetics providers and there little consensus on whether this finding should be disclosed. Discussions in the literature are highly theoretical, with limited research regarding how disclosure decisions enacted practice. We explored genetic counselors' (GCs) clinical experiences NP to understand if, how, why communicated. Our semi‐structured interviews counselors United States Canada were analyzed using reflexive thematic analysis...
A new variant of SARS-CoV-2 (Lineage B.1.1.7) was identified in the UK December 2020 which associated with higher transmissibility COVID-19. The AusDiagnostics SARS-CoV-2, Influenza and RSV 8-well assay is used at sixteen hospitals detects part ORF8 gene (together a segment from ORF1a gene). objective this study to determine if recently mutation (G28048T) B.1.1.7. lineage could be identify quickly clinical cases PCR positive results. melt data positives two (October through 2020) were...