About
Contact & Profiles
A5095894257
Research Areas
- CAR-T cell therapy research
- Viral Infectious Diseases and Gene Expression in Insects
- Silicon Carbide Semiconductor Technologies
- Nanowire Synthesis and Applications
RMIT University
2024
This article for the Highlights of 2023 Series explores recent work that suggests targeting CD4 CAR T cells may be critical both these challenges.
10.1111/imcb.12764
article
EN
Immunology and Cell Biology
2024-04-24
Abstract Objectives In clinical chimeric antigen receptor (CAR) T cell therapy, one of the strongest correlates favorable patient responses is lower levels differentiation in cells from peripheral blood mononuclear (PBMC) starting material or CAR product. older patients are inherently more differentiated, but we hypothesised that specific activation protocols could be used to limit during manufacturing, particularly patients. Methods We PBMCs young (20–30 years old) and (60+ healthy donors...
10.1002/cti2.70016
article
EN
cc-by
Clinical & Translational Immunology
2024-01-01
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