Jan Barć

ORCID: 0009-0004-8087-6252
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About
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Research Areas
  • CAR-T cell therapy research
  • Wound Healing and Treatments
  • Acne and Rosacea Treatments and Effects
  • Genetics and Physical Performance
  • Angiogenesis and VEGF in Cancer
  • Plant-based Medicinal Research
  • Mesenchymal stem cell research
  • Tendon Structure and Treatment
  • Dermatologic Treatments and Research
  • Diabetic Foot Ulcer Assessment and Management
  • Nutrition, Genetics, and Disease
  • Dialysis and Renal Disease Management

Medical University of Lublin
2023-2024

Background: We performed gene therapy for critical limb ischemia in thromboangiitis obliterans (TAO) by the intramuscular administration of plasmids vascular endothelial growth factor (VEGF 165) with or without bone marrow-derived stem cells. Methods: The 21 patients were randomly assigned to three groups: A—with dual therapy, cells and plasmid; B—plasmid only; C—control group, where received injections saline. Serum VEGF levels, ankle–brachial index (ABI), transcutaneous oxygen pressure...

10.3390/biomedicines12071506 article EN cc-by Biomedicines 2024-07-06

Diabetic foot syndrome (DFS) is one of the most serious macroangiopathic complications diabetes. The primary treatment option revascularization, but complementary therapies are still being sought. study group consisted 18 patients diagnosed with ischemic ulcerative and necrotic lesions in DFS. Patients underwent revascularization procedures and, due to unsatisfactory healing lesions, were randomly allocated two groups: a which bicistronic VEGF165/HGF plasmid was administered control saline...

10.3390/genes14101968 article EN Genes 2023-10-20

Introduction and purpose: All over the world, patients suffer from chronic kidney disease (CKD) end-stage (ESRD). Patients can choose to undergo hemodialysis in a specialist center or use peritoneal dialysis their own home. The aim of this study is answer question which above methods has better impact on quality life patients.
 Materials methods: literature available PubMed, Scopus Google Scholar was reviewed using words “peritoneal dialysis”; “hemodialysis”; “quality life”.
...

10.12775/jehs.2023.42.01.006 article EN cc-by-nc-sa Journal of Education Health and Sport 2023-07-04

Rosacea is a chronic inflammatory disease that usually affects the central part of face. The primary symptoms include facial flushing, persistent erythema, telangiectasia, pustules and papules. Based on groups these symptoms, four basic rosacea subtypes have been defined: erythematotelangiectatic, papulopustular, ocular, phymatous; one variant, granulomatous rosacea. Although pathophysiology this disorder not fully known, many components such as immune neurovascular dysregulation, oxidative...

10.12775/jehs.2023.18.01.011 article EN cc-by-nc-sa Journal of Education Health and Sport 2023-07-18
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