A5102906359- RNA Interference and Gene Delivery
- Reproductive System and Pregnancy
- Pregnancy and Medication Impact
- Eosinophilic Esophagitis
- Nanofabrication and Lithography Techniques
- Advanced Biosensing Techniques and Applications
- Advanced biosensing and bioanalysis techniques
- Viral Infections and Immunology Research
- Nanoparticle-Based Drug Delivery
- Click Chemistry and Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Cytokine Signaling Pathways and Interactions
- Galectins and Cancer Biology
- Connective tissue disorders research
- Protease and Inhibitor Mechanisms
University of Minho
2019-2025
Sage (United Kingdom)
2013
Université Paris Cité
2013
Introduction: The development of novel drug carriers is invaluable to maximize therapeutic efficiency and improve specificity. Dioctadecyl-dimethylammonium bromide (DODAB): monoolein (MO) (1:2) liposomes exhibit non-lamellar phases in their core that the encapsulation ability both hydrophobic hydrophilic molecules. This study explores use this nanosystem for delivery cytokines, specifically leukemia inhibitory factor (LIF). Nanocarriers can overcome drawbacks direct cytokine administration,...
Oncostatin M (OSM) and leukemia inhibitory factor (LIF) are pleiotropic cytokines from the interkeukine-6 family, associated with several disorders, present significant potential in biomedicine. However, their therapeutic use is highly constrained by factors such as short circulating half-life narrow window. The conjugation of elastin-like recombinamers (ELR) holds to circumvent these limitations due ability self-assembling upon a thermal stimulus, remarkable biocompatibility, ease...