A5091348570- Fluid Dynamics and Vibration Analysis
- Aerodynamics and Fluid Dynamics Research
- Lattice Boltzmann Simulation Studies
- Essential Oils and Antimicrobial Activity
- Vibration and Dynamic Analysis
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Bioactive Compounds and Antitumor Agents
- Cannabis and Cannabinoid Research
- Medicinal Plant Research
- Synthesis of Tetrazole Derivatives
- melanin and skin pigmentation
- Computational Drug Discovery Methods
- Click Chemistry and Applications
- Diet, Metabolism, and Disease
- Plant biochemistry and biosynthesis
- Enzyme function and inhibition
- Multicomponent Synthesis of Heterocycles
- Allelopathy and phytotoxic interactions
- GABA and Rice Research
- Photochromic and Fluorescence Chemistry
- Nigella sativa pharmacological applications
- Recycling and utilization of industrial and municipal waste in materials production
- Phytochemicals and Antioxidant Activities
- Insect Pest Control Strategies
Air University
2023-2025
The Women University Multan
2017-2024
Bahauddin Zakariya University
2024
Introduction: Cancer is the second most prevalent cause of mortality in world, despite availability several medications for cancer treatment. Therefore, research community emphasized on computational techniques to speed up discovery novel anticancer drugs. Methods : In current study, QSAR-based virtual screening was performed Zinc15 compound library (271 derivatives methotrexate (MTX) and phototrexate (PTX)) predict their inhibitory activity against dihydrofolate reductase (DHFR), a...
Abstract This study evaluated the volatile components of Cannabis sativa L. essential oils (CSEOs) and their pharmacological potential in vitro , animal, silico . The anti-oxidant capacities compounds were tested using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP), total capacity (TAC), gas chromatography-mass spectrometry (GC-MS). Anti-microbial activity against bacterial fungal strains was assessed disk diffusion micro-dilution, acute toxicity examined on...
Abstract This study investigates the influence of small control cylinders on fluid dynamics around a square cylinder using Lattice Boltzmann Method (LBM). Varying gaps (L) between main and from 0 to 6, four distinct flow regimes are identified: solo body regime (SBR), shear layer reattachment (SLR), suppressed fully developed (SFDF), intermittent shedding (IS). The presence results in significant reductions flow-induced forces, with drag coefficient (CD) root mean values lift coefficients (...
Abstract Dicliptera is a genus belonging to family Acanthaceae. bupleuroides small perennial herb commonly known as roxburg's foldwing. It locally used in folkloric medicines for the treatment of different diseases and general tonic wound healing. The current investigational study was optimize solvent extraction protocol, identify quantitative qualitative biochemical composition, antioxidant cytotoxic activities D. characterize gene associated with biosynthesis flavonol. plant collected from...
Developing new anti-tyrosinase drugs seems crucial for the medical and industrial fields since irregular melanin synthesis is linked to resurgence of several skin conditions, including melanoma, browning fruits vegetables. A novel series N-1 C-3 substituted indole-based thiosemicarbazones 5(a-r) are synthesized further analyzed their inhibition potential against tyrosinase enzyme through
Flavokawain B (FKB) is a naturally occurring chalcone that exhibits potential anti-cancer properties. Density functional theory (DFT) computational simulation approach used to investigate the electronic properties of molecules. Here, we investigated structural-activity relationship and optoelectronic chalcones; FKB their derivatives named (E)-3’-(2’-fluorophenyl)-1’-(2’-hydroxy-4and#39;,6and#39;-dimethoxyphenyl)prop-2-en-1-one (KG1),...
In this study, control over the wake flow of a single square cylinder exercised by flat plate attached to rear side is analyzed numerically via lattice Boltzmann method. The Reynolds number ( <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="m1"><mml:mrow><mml:mi>R</mml:mi><mml:mi>e</mml:mi></mml:mrow></mml:math> ) fixed at 150, and length varied from 0.1 8.5. Three distinct modes are observed in study: unsteady, transient, steady cases lengths...
This article is concerned with the numerical analysis of reduction fluid forces (drag and lift) suppression vortex shedding around two side‐by‐side square cylinders using lattice Boltzmann method. For this purpose, a passive flow control methodology adopted in which flat plate (termed as plate) placed at upstream position cylinders. The gap ratio ( g ) between varied from 0 to 4 while height 0.2 0.8 fixed Reynolds number 150. Different patterns are found study depending on ratios different...
This work intended to study differences in oil yield and co-extraction of antioxidant antibacterial compounds Nigella sativa L. seed as a function two main extraction processes: mechanical pressing solvent extraction, including hexane chloroform. Next, we studied such oils' chemical composition activities. Notably, the cartelization was conducted by use HPLC. The activity oils assessed using DPPH, TAC, FRAP assays. Antimicrobial investigated against bacteria fungi with clinical importanceT....
Conventional roofing tiles, composed of either clay or concrete, are considered as environmentally unfriendly since a substantial quantity greenhouse gases is being discharged in their production. In this study, an alternate approach utilizing vegetable oil proposed to produce tiles called ‘green tiles’. It believed that extended heat curing may convert into rigid binder after undergoing series complex autocatalytic oxy-polymerization reactions. These green have flexural strength up...
This study aims to numerically investigate the optimal conditions for fluid flow control around a single square cylinder with help of pair attached flat plates. It is comparatively new approach controlling flows as compared traditional solo plate devices. The plates are adjacent both rear corners and their length (l) varied from [Formula: see text] 4 times size main while fixing height (h) at text]. By varying length, manage gradually. discusses how steady wake can be achieved through...
Background Acacia nilotica is a multipurpose plant known for its remedial properties but the antimicrobial and hepatoprotective activity of pods remained unexplored. Objective This study aimed to evaluate n-hexane (ANPH) methanol (ANPM) extracts scientifically validate their medicinal claims. Methods After pharmacognostic evaluation pods, in vitro tests were carried out estimate phenolic flavonoid content potential. In vivo experiments involved testing both (250 500 mg/kg) paracetamol...
Moroccan Cannabis sativa L. seeds were investigated for their phenolic profile and antidiabetic potential. Ultra-high-performance liquid chromatography with diode array detection electrospray ionization mass spectrometry analysis revealed a rich composition, including benzoic acid, cannabisin B, genistein, epicatechin. In vitro, the seed extract exhibited potent α-amylase inhibitory activity (half-maximal concentration = 25.02 ± 4.03 μg/mL). vivo studies in diabetic rats demonstrated...