The development of green technology is creating great interest for researchers towards low-cost and environmentally friendly methods the synthesis nanoparticles. Copper oxide nanoparticles (CuO-NPs) attracted many due to their electric, catalytic, optical, textile, photonic, monofluid, pharmacological activities that depend on shape size This investigation aims copper using Aerva javanica plant leaf extract. Characterization synthesized by route was performed three different techniques:...

The present study deals with the advanced in-silico analyses of several Apigenin derivatives to explore human papillomavirus-associated cervical cancer and DNA polymerase theta inhibitor properties by molecular docking, dynamics, QSAR, drug-likeness, PCA, a dynamic cross-correlation matrix quantum calculation properties. initial literature revealed potent antimicrobial anticancer Apigenin, prompting selection its potential investigate their abilities as inhibitors theta. In silico docking...

Cistus albidus : L., also known as Grey-leaved rockrose and locally addressed šṭab or tûzzâla lbîḍa, is a plant species with well-established reputation for its health-promoting properties traditional use the treatment of various diseases. This research delves into exploring essential oil extracted from aerial components (referred to CAEO), aiming comprehend concerning antioxidation, anti-inflammation, antimicrobial efficacy, cytotoxicity. Firstly, comprehensive analysis CAEO’s chemical...

This study presents the fabrication and characterization of mixed matrix membranes (MMMs) incorporating green-synthesized silver nanoparticles (AgNPs) using Hibiscus Rosa sinensis extract within a polyethersulfone (PES) for nanofiltration (NF) application. The were evaluated their pure water permeability, salt rejection, dye removal, antifouling performance. Results showed that membrane with 0.75 wt% AgNPs exhibited highest permeability 36 L/m2 h−1 bar−1 attributed to increased porosity...

This study investigated the chemical composition, antioxidant and antimicrobial activity of essential oil extracted from Artemisia aragonensis Lam. (EOA). Hydrodistillation was employed to extract EOA. Gas chromatography with flame ionization detection (GC-FID) gas chromatography-mass spectrometry analyses (GC-MS) were used determine phytochemical composition Antioxidant potential examined in vitro by use three tests: 2.2-diphenyl-1-picrilhidrazil (DPPH), ferric reducing power (FRAP) total...

Antioxidant, antifungal and insecticidal activities of essential oil (EO) extracted from the Moroccan lavender (Lavandula dentata) were investigated their chemical constituents determined. Gas chromatography with flame ionization detection (GC-FID) gas chromatography-mass spectrometry analyses (GC-MS) used to examine phytochemical composition EO. Antioxidant potential was examined in vitro by use three tests: DPPH inhibition, reducing power (FRAP) total antioxidant capacity (TAC). Antifungal...

A series of new heterocycle hybrids incorporating pyrazole and isoxazoline rings was successfully synthesized, characterized, evaluated for their antimicrobial responses. The synthesized compounds were obtained utilizing N-alkylation 1,3-dipolar cycloaddition reactions, as well structures established through spectroscopic methods confirmed by mass spectrometry. To get more light on the regioselective synthesis hybrid compounds, mechanistic studies performed using DFT calculations with...

Abstract The current work attempts to explore the influence of three extraction solvents on phytochemical composition, content polyphenols, antioxidant potential, and antibacterial capacity hydroethanolic, acetonic, aqueous extracts from Moroccan Mentha longifolia leaves. To achieve this goal, chemical composition was identified using an HPLC–DAD examination. contents polyphenols were assessed, while total (TAC), DPPH test, reducing power test (RP) utilized determine capacity. assess...

This study aims to the impact of environmental stresses on chemical compositions essential oils and content secondary metabolites plants most used by rural population: Thymus vulgaris, Mentha pulégium Rosmarinus officinalis. The results indicate that percentage increased in second year when temperature water pressure 50%. Specifically, coumarin from 3.94% 9.23%, saponins 6.17% 7.78%, tannins 2.90% 6.12%, alkaloids 6.72% 15.95%, flavonoids 7.42% 12.90%. However, fourth year, continued...

The mastic tree, scientifically known as Pistacia lentiscus, which belongs to the Anacardiaceae family, was used in this study. aim of research analyze chemical composition plant and assess its antioxidant antibacterial properties using both laboratory experiments computer simulations through molecular docking, a method that predicts binding strength small molecule protein. soxhlet (SE) employed extract substances from leaves P. lentiscus found eastern region Morocco. Hexane methanol were...

Abstract Generally wastewater such agricultural runoff is considered a nuisance; however, it could be harnessed as potential source of nutrients like nitrates and phosphates in integrated biorefinery context. In the current study, microalgae Chlorella sp. S5 was used for bioremediation leftover algal biomass production biofuels an The cultivated on Blue Green (BG 11) medium comprehensive optimization different parameters including phosphates, nitrates, pH carried out to acquire maximum...

Abstract The aim of the present study was to assess drinking water quality in selected urban areas Lahore and comprehend public health status by addressing basic parameters. Total 50 tap samples were collected from groundwater two district i.e., Gulshan-e-Ravi (site 1) Samanabad 2). Water analyzed laboratory elucidate physico-chemical parameters including pH, turbidity, temperature, total dissolved solids (TDS), electrical conductivity (EC), oxygen (DO), hardness, magnesium calcium hardness....

Abstract Breast cancer has rapidly increased in prevalence recent years, making it one of the leading causes mortality worldwide. Among all cancers, is by far most common. Diagnosing this illness manually requires significant time and expertise. Since detecting breast a time-consuming process, preventing its further spread can be aided creating machine-based forecasts. Machine learning Explainable AI are crucial classification as they not only provide accurate predictions but also offer...

Background: Structure–activity relationship (SAR) is considered to be an effective in silico approach when discovering potential antagonists for breast cancer due gene mutation. Major challenges are faced by conventional SAR predicting novel the discovery of diverse antagonistic compounds. Methodologyand Results: In antagonists, a multistep screening phytochemicals isolated from seeds Citrus sinensis plant was applied using feasible complementary methodologies. A three-dimensional...

This work aimed to evaluate the inhibitory effect of main polyphenols and flavonoids Syzygium aromaticum Citrus limon as well organosulfur compounds Allium sativum against SARS-CoV-2 6LU7 6Y2E proteases using in silico molecular docking analysis. Structures 34 natural products found three medicinal plants were docked these two critical proteins. For protease, 24 exhibited binding affinities greater than or equal -6 Kcal/mol. While, for 6 Molecules with a maximum affinity -8.4 kcal/mol show...

Abstract This work examines the capacity of Naringin and Rutin to influence DNA damage response (DDR) pathway by investigating their interactions with key DDR proteins, including PARP-1, ATM, ATR, CHK1, WEE1. Through a combination in silico molecular docking vitro evaluations, we investigated cytotoxic genotoxic effects these compounds on MDA-MB-231 cells, comparing them normal human fibroblast cells (2DD) quiescent (QFC). The research found that had strong affinities for indicating...

The study was designed to explore the corrosion prevention capabilities of Citrullus colocynthis seeds alkaloid-rich extract (CSEA) on MS in a 1 M HCl environment by use electrochemical and theoretical methods. Notably, Electrochemical Impedance Spectroscopy (EIS) potentiodynamic polarization were used probe impact immersion time temperature. Energy-dispersive X-ray spectroscopy (EDX) spanning electron microscopy (SEM) confirm presence protective layer substrate surface. Density functional...

Human rhinovirus C (HRV-C) is a significant contributor to respiratory tract infections in children and implicated asthma exacerbations across all age groups. Despite its impact, there currently no licensed vaccine available for HRV-C. Here, we present novel approach address this gap by employing immunoinformatics techniques the design of multi-epitope-based against The sequences chosen structural proteins VP1 VP2, along with non-structural protein 2C HRV-C, were downloaded FASTA format from...

Maize (Zea mays L.) growth and yield are severely affected due to intraspecific competition agroclimatic conditions when cultivated with high plant densities. Field trials comprising four daily thinning patterns (0, 0.5, 1.0, &1.5% till silking) carried out in three consecutive years (2019-2021) using RCBD experimental design consisting of replicates. Growth variables, dry matter allocation rates maize were examined during five biweekly periods starting from the emergence (15, 30, 45, 60 75...

Medicinal plants played an important role in traditional medicine for the treatment of diseases since antiquities. The aim study is to carry out ethnobotanical survey on medicinal used traditionally cancer region Greater Casablanca-Morocco, and enhance herbal knowledge. 110 healers area were interviewed face response a questionnaire including names treatment, parts, methods preparation, route administration. Indices Fidelity Level (FL), Use Value (UV), Relative Frequency Citation (RFC)...

Background: Anacyclus pyrethrum (A. pyrethrum) is a wild species belonging to the family Asteraceae, which used in traditional medicines. Aim of study: This work was undertaken study chemical composition, analgesic, anti-inflammatory, and wound healing properties hydroalcoholic extracts different parts (roots, seeds, leaves, capitula) A. pyrethrum. Material Methods: The phytochemical analysis studied conducted by GC-MS. analgesic activity evaluated mice using acetic acid formaldehyde...

Since their existence on earth, humans have used herbal medicine to meet requirements for medication. The aim of the study: This work refers a study conducted carry out an ethnopharmacological survey medicinal plants treatment cancer in Fez-Meknes region Morocco. Material and Methods: To achieve this goal, 300 informants including 237 local people 63 herbalists. They were requested fill related questionnaire aiming at collection data about addressed objective. Informants asked vernacular...

In this work, two varieties of Anacyclus pyrethrum (L.) including var. and depressus (Ball) Maire were evaluated for their mineral chemical compositions, total phenolic flavonoid contents, antimicrobial antioxidant activities using hydroalcoholic extracts from different parts (leaves, capitula, roots, seeds). The phytochemical compositions carried out standard methods. activity was determined the DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2-azino-bis 3-ethylbenzothiazolin-6-sulfonic...