A5050517965- Thermal Regulation in Medicine
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Hematological disorders and diagnostics
- Lymphatic System and Diseases
- Immune Response and Inflammation
- Biochemical effects in animals
- Thermoregulation and physiological responses
- Chemical and Physical Studies
- Inflammasome and immune disorders
- Immunotoxicology and immune responses
- Exercise and Physiological Responses
- Electrolyte and hormonal disorders
- Viral Infections and Vectors
- Digestive system and related health
- Pediatric health and respiratory diseases
- Lymphatic Disorders and Treatments
- Vector-borne infectious diseases
- Mast cells and histamine
- Inhalation and Respiratory Drug Delivery
- Effects of Radiation Exposure
- Apelin-related biomedical research
- Alkaline Phosphatase Research Studies
- T-cell and Retrovirus Studies
- Cancer therapeutics and mechanisms
- Hereditary Neurological Disorders
Kazan State Medical University
1995-2023
Ministry of Health of the Russian Federation
2023
Research Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences
2004
Introduction . Mitotic poisoning agents (MPAs) affecting the dynamic state of microtubules, are well-known and effective chemotherapeutic agents. binding to thereby interfere with tubulin polymerization or depolymerization state, resulting in cell cycle arrest M-phase (mitotic catastrophe) subsequent apoptotic death. We reported previously about potent cytotoxic activities against pyrrole-carboxamides (PCs) (PC-61 PC-84) broad spectrum cancer lines, including triple negative breast cancer,...