A5101463733- Cancer Research and Treatments
- MicroRNA in disease regulation
- Shoulder and Clavicle Injuries
- Shoulder Injury and Treatment
- Neuroscience of respiration and sleep
- Cancer-related molecular mechanisms research
- Corneal surgery and disorders
- Organ Transplantation Techniques and Outcomes
- Aortic Disease and Treatment Approaches
- Glaucoma and retinal disorders
- Circular RNAs in diseases
- Aortic aneurysm repair treatments
- Hepatitis B Virus Studies
- Intraocular Surgery and Lenses
- Drug Transport and Resistance Mechanisms
- Enhanced Recovery After Surgery
- Cancer and Skin Lesions
- Gastrointestinal motility and disorders
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Nanoparticle-Based Drug Delivery
- Kruppel-like factors research
- Cancer Mechanisms and Therapy
- Neonatal Health and Biochemistry
- Testicular diseases and treatments
Nanjing University of Chinese Medicine
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Bengbu Medical College
2023-2024
Beibu Gulf University
2023
Soochow University
2022
Jiangxi Maternal and Child Health Hospital
2021
Second Military Medical University
2018-2019
Changhai Hospital
2018-2019
First Hospital of Shanxi Medical University
2016
Shanxi Medical University
2016
Previous studies reported that miR-330-3p was involved in the progression of several cancers, but potential roles ovarian cancer (OC) were unclear. In current study, we aimed to explore expression pattern and functions OC. The level OC tissues cell lines detected using RT-qPCR. proliferation, migration invasion cells CCK-8 assay transwell assay, respectively. Bioinformatics analysis luciferase reporter used analyze targeted binding site RIPK4. results showed significantly downregulated...
Aims and background A former study evaluated the roles of four multidrug resistance-related proteins, namely resistance protein 1 (MDR1), breast cancer (BCRP), (MRP1), lung (LRP), in MDR mechanism resistant hepatoma HepG2/ADM cell line proposed that up-regulated MDR1 BCRP are responsible for hepatocellular carcinoma. This work aims to confirm assumption vivo clinical specimens. Methods First, chemotherapeutic subcutaneous tumor carcinoma samples post-transarterial chemoembolization (TACE)...
This study examined the relationship between loneliness, sedentary behavior, physical exercise, and social participation in Chinese older adults, provided ideas to formulate preventive strategies that can help reduce loneliness. Data on demographics, health participation, loneliness were collected from a cross-sectional of 629 adults Hefei, Anhui province, June August 2020. After adjusting for age, income, religion, marital status, chronic illness demographic variables, behavior (β = 0.111,...
BACKGROUND Midazolam, a commonly used sedative, faces challenges in cancer therapy due to its central nervous system (CNS) toxicity and suboptimal targeting of tumor sites. This study explores the use poly (lactic-co-glycolic acid) (PLGA) nanoparticles enhance delivery aiming improve antitumor efficacy while minimizing CNS toxicity. MATERIAL AND METHODS We developed Midazolam-loaded PLGA (Midazolam NPs) using ultrasonic emulsification-solvent evaporation technique. These were thoroughly...
Endoscopic treatment of early colon neoplasms has evolved as a valid and less traumatic alternative to surgical resection. It can usually be performed with sedation on an outpatient basis. The present study was determine the safety effectiveness electroacupuncture (EA) versus propofol during endoscopic submucosal dissection (ESD) for neoplasm. A total 150 adult outpatients undergoing ESD were selected divided into EA combined group (EP group), remifentanil (RP (SP 50 patients in each group....
<title>Abstract</title> Fibromatosis-like metaplastic carcinoma (FLMC) is a rare and distinct subtype of breast (MBC), comprising 4–8% cases. Characterized by triple-negative receptor profile low proliferative activity, FLMC exhibits less aggressive clinical behavior compared to other MBC subtypes. However, due its rarity, knowledge pathological features, treatment outcomes, prognosis remains limited. This multicenter retrospective cohort study included 21 cases diagnosed between November...
To develop a comprehensive training course for ICU nurses in prone positioning.
Locoregional chemotherapy continues to be the mainstay for treatment of unresectable hepatocellular carcinoma (HCC). One principal obstacles implicated in its unsuccessful therapy is multidrug resistance (MDR). Former studies have identified multidrug-resistant nature and possible mechanisms hepatoma cells both vitro vivo. This work aimed develop an effective strategy HCC with MDR.The was exploited inhibit MDR by co-administration recombinant mutant human tumour necrosis factor-alpha...
Our goal was to examine whether interleukin-1 beta (IL-1β) originates locally and its possible relationship with matrix metalloproteinases (MMPs), apoptosis, elastin fibres biomechanics in aortic dissecting aneurysms (DAs). Aortic DAs were induced 24 rats β-aminopropionitrile (BAPN); another 12 without BAPN designated as controls. Then IL-1β levels measured both the circulation local specimens. The expression of MMP-2 MMP-9 Victoria blue TUNEL staining also detected. Biomechanical parameters...
This study was performed to examine the relationship between C-reactive protein/albumin ratio (CAR) and prognosis of patients with lung adenocarcinoma thus provide a reference for evaluating adenocarcinoma.The clinical data 130 were retrospectively collected analyzed. The patients' overall survival (OS) time calculated, factors affecting OS statistically analyzed.The CAR correlated sex, stage, brain metastasis, S100 calcium-binding protein B (S100B), interleukin 17, myelin basic protein,...
Focal adhesion kinase (FAK), which plays a pivotal role in mediating cell proliferation, survival and migration, is frequently overexpressed human colon cancer. In the present study, we utilized short hairpin RNA (shRNA) to knock down expression of FAK SW480 cancer cells vitro. Furthermore, nude mice bearing carcinoma were established treated with plasmids encoding shRNA encapsulated DOTAP: Chol cationic liposome through tail vein injection. Tumor growth potential side effect observed during...
To explore a new treatment that can proceed from the whole, control blood pressure smoothly and coordinate of multiple factors causing fluctuations.We conducted single-center, double-blinded, randomized controlled clinical trial. 48 patients with acute Type B aortic dissection were randomly assigned into two groups: experimental group, who received pinggan formula treatment, placebo treatment. The drug was taken orally after meals three times day. Only when patients' fluctuated, conventional...
To investigate the expression level and regulation mechanism of miR-720 as well association with leukemia biological characteristics.Expression promoter methylation were determined by quantitive PCR pyrosequencing in 38 patients AML 20 normal controls. Lentivirous-mediated miR-702 overexpression was constructed cell line kasumi-1. The proliferation, apoptosis, cycle, colony formation, migration P53-mediated apoptosis pathway determined.AML showed significantly lower compared controls...