- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Cardiac Valve Diseases and Treatments
- Infectious Aortic and Vascular Conditions
- Vascular Procedures and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Peripheral Artery Disease Management
- Coronary Interventions and Diagnostics
- Abdominal vascular conditions and treatments
- Cerebrovascular and Carotid Artery Diseases
- Infective Endocarditis Diagnosis and Management
- Venous Thromboembolism Diagnosis and Management
- Renal and Vascular Pathologies
- Soft Robotics and Applications
- Diagnosis and Treatment of Venous Diseases
- Central Venous Catheters and Hemodialysis
- Intracranial Aneurysms: Treatment and Complications
- Cardiac and Coronary Surgery Techniques
- Hip and Femur Fractures
- Vasculitis and related conditions
- Traumatic Ocular and Foreign Body Injuries
- Cardiovascular Health and Disease Prevention
- Cardiac Structural Anomalies and Repair
- Vascular anomalies and interventions
- Trauma Management and Diagnosis
Changhai Hospital
2016-2025
Second Military Medical University
2016-2025
Ningbo University
2025
Wenzhou Medical University
2025
Naval Medical Research Command
2022
Beijing Urban Construction Design & Development Group (China)
2021
Zero to Three
2017
Jacobson Holman (United States)
2014
National Natural Science Foundation of China
2013
Donghua University
2013
Endovascular repair of thoracic aneurysm has demonstrated low risks mortality and spinal cord ischemia (SCI), but few large series have been published on endovascular thoracoabdominal repair, reports suffer from a lack accurate comparison with similar open surgical procedures.A consecutive cohort patients aneurysms treated electively (ER) or (SR) techniques between 2001 2006 were analyzed. The association technique SCI was evaluated univariable analysis. Adjustments for potential confounders...
Few studies have evaluated the clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with bicuspid stenosis (AS). Particularly, limited data exist comparing results TAVR new-generation devices versus early-generation devices. This study sought to evaluate for AS early- and The Bicuspid Registry is an international multicenter enrolling consecutive undergoing between April 2005 May 2015. Of 301 patients, 199 (71.1%) were treated (Sapien XT [Edwards Lifesciences...
Computational modelling to calculate the mechanical loading within atherosclerotic plaques has been shown be complementary defining anatomical plaque features in determining vulnerability. However, its application partially impeded by lack of comprehensive knowledge about properties various tissues plaque. Twenty-one human carotid were collected from endarterectomy. The was cut into rings, and different type tissues, including media, fibrous cap (FC), lipid intraplaque haemorrhage/thrombus...
There is no approved special endovascular device for use in preventing entry tears the distal part of ascending aorta or aortic arch and preserving branch arteries. Thus, we have designed a novel branched stent-graft, herein report initial clinical outcomes.Between August 2009 January 2014, 51 patients with dissections involving were treated by stent-grafts. 7 Stanford type A dissections, 22 retrograde B (including 4 localized dissections). All while chronic phase (>2 weeks).All proximal...
Purpose:To evaluate the incidence and natural history of endoleaks following thoracic endovascular aortic repair (TEVAR) aneurysm (TAA). Methods:A retrospective review was conducted on 200 TAA patients (122 men; mean age 69±12 years) who underwent elective TEVAR in descending aorta between January 2001 December 2006. The diameter 66 mm (range 50–124), most (75%) aneurysms were atherosclerotic origin. Medical records multidetector computed tomography studies evaluated a 3-dimensional...
To find a suitable rate of thoracic stent-graft oversizing by exploring its association with the occurrence retrograde type A dissection (RTAD) after endovascular aortic repair (TEVAR) for B dissection.From January 2013 to June 2014, 203 patients (mean age 55 years; 167 men) underwent TEVAR. The mean at proximal landing zone was 10% (range 0%-32%). Patients were stratified into 2 groups based on degree oversizing: ≤5% (n=105, 1.2%±1.5%) and >5% (n=98, 18.5%±2.8%). TEVAR-related...
Mechanical analysis has the potential to provide complementary information aneurysm morphology in assessing its vulnerability. Reliable calculations require accurate material properties of individual aneurysmal components. Quantification extreme extensibility and ultimate strength tissue are important if rupture is be modelled. Tissue pieces from 11 abdomen aortic (AAA) patients scheduled for elective surgery 8 normal artery (NAA) who kidney/liver transplant were collected at banked liquid...
Purpose: To evaluate the midterm outcomes of thoracic endovascular aortic repair (TEVAR) using chimney grafts (ch-TEVAR) or stent-grafts with fenestrations made on back table (f-TEVAR) to treat dissection (TAD) and aneurysm (TAA). Materials Methods: A retrospective analysis was conducted 474 consecutive patients (mean age 62.3±10.7 years; 346 men) treated either f-TEVAR (n=110) ch-TEVAR (n=364) for 352 TADs (81 271 ch-TEVAR) 122 TAAs (29 93 from 2008 2016. The primary endpoints at 30 days...
BackgroundStent graft-induced distal redissection (SIDR) is one of the major concerns in durability endovascular repair for complicated Stanford type B aortic dissection. The characteristics and means prevention this complication remain unknown.MethodsFrom April 1997 to March 2010, 674 patients with dissections were treated primarily by thoracic (TEVAR) at our center. Criteria inclusion study treatment TEVAR an estimated mismatch rate (ratio diameter stent graft long true lumen) greater than...
Acute aortic dissection (AAD) is a catastrophic emergency with high mortality and misdiagnosis rate. We aimed to determine whether circulating microRNAs allow distinguish AAD from healthy controls chest pain patients without (CP). Plasma expression were determined in 103 participants, including 37 patients, 26 chronic 17 volunteers, 23 AAD. selected 16 microarray screening as candidates for further testing via qRT-PCR. The results showed that plasma miR-15a (n = 37) had significantly higher...
To examine the expression of interleukin-1β and interferon-γ their possible roles in aortic dissections aneurysms.Aortic specimens were obtained from patients with type I thoracic dissection, ascending aneurysms, control organ donors. The interleukin-1β, interferon-γ, matrix metalloproteinase-9, signal transduction factors phospho-p38 phosphorylated c-jun N-terminal kinase (phospho-JNK) detected by real time reverse transcription-polymerase chain reaction (real RT-PCR), Western blot,...