A5100449978- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Sarcoma Diagnosis and Treatment
- Pelvic and Acetabular Injuries
- Scoliosis diagnosis and treatment
- Orthopaedic implants and arthroplasty
- Metal complexes synthesis and properties
- Spinal Cord Injury Research
- Bone Tumor Diagnosis and Treatments
- Renal Diseases and Glomerulopathies
- Orthopedic Infections and Treatments
- Vasculitis and related conditions
- Cervical and Thoracic Myelopathy
- Total Knee Arthroplasty Outcomes
- Vascular anomalies and interventions
- Skin Protection and Aging
- Sleep and related disorders
- Nerve injury and regeneration
- Natural Compounds in Disease Treatment
- Frailty in Older Adults
- Neurofibromatosis and Schwannoma Cases
- Traditional Chinese Medicine Studies
- Spinal Dysraphism and Malformations
- Anatomy and Medical Technology
- Trauma Management and Diagnosis
National Taiwan University of Science and Technology
2018-2025
Second Military Medical University
2012-2023
Shandong University
2023
Shanghai Changzheng Hospital
2017-2023
Fuzhou University
2023
Changhai Hospital
2009-2021
Affiliated Hospital of Southwest Medical University
2019
Saint Louis University Hospital
2016
Chinese Academy of Medical Sciences & Peking Union Medical College
2016
Peking Union Medical College Hospital
2016
Transplantation of olfactory ensheathing cells (OECs) has emerged as a very promising therapy for spinal cord injury (SCI). Also, local delivery NT-3 can counteract pathological events and induce regenerative response after SCI. Supplement exogenetic might be new approach to SCI repair. In this study, we examined the therapeutic effect rat gene-modified OECs transplantation on Rat gene was transfected into using retroviral system. The engineered NT-3-OECs were tested their ability express...
Retrospective, comparative study.To compare the effects of anterior rod-screw instrumentation and posterior pedicle screw on sagittal balance in patients with Lenke type 5 adolescent idiopathic scoliosis (AIS).Lenke AIS is treated by or spinal fusion surgery. Most studies comparing surgery have focused assessing improvement coronal balance. Studies are lacking.The records 49 diagnosed were examined. A total 21 underwent between 2000 2003, while 26 2004 2006. Preoperative, postoperative,...
Severe adenovirus pneumonia and its associated imaging features are well-described in immunocompromised patients but rare poorly understood immunocompetent adults. We sought to describe the radiographic CT findings of severe community-acquired (CAP) eight adults.We reviewed systematically chest manifestations laboratory-confirmed adults from April 2012 2014.All showed abnormal results on initial radiograph CT, with exception one normal radiograph. The abnormalities radiographs were...
Limb salvage reconstruction for pelvic tumors, especially periacetabular is challenging. We combined the use of dual mobility bearing and 3D-printed hemipelvic prosthesis to improve function reduce probability complications after hemi-pelvic resection in patients with primary acetabular malignancy. The purpose this study was evaluate efficacy safety combination.Between October 2011 May 2021, 11 malignancies involving acetabulum received replacement a bearing. Follow-up postoperative...
In the published publication [...]
Melatonin has been shown to diminish edema in rats. can be used treat spinal cord injury. This study presumed that melatonin could relieve and examined how it might act. Our experiments found (100 mg/kg, i.p.) reduce the water content of cord, suppress expression aquaporin-4 glial fibrillary acidic protein after suggests mechanism by which alleviates damage related protein.
OBJECT The object of this study was to review the effectiveness in treating severe and rigid scoliosis with posterioronly spinal release combined derotation, translation, segmental correction, an situ rod-contouring technique. METHODS Twenty-eight patients (Cobb angle > 70° flexibility < 30%) were retrospectively enrolled between June 2008 2010. average age 17.1 years old (range 12–22 old), 18 female, 10 male. Etiological diagnoses idiopathic 24 patients, neuromuscular 2 Marfan...
The present study aimed to investigate the effect of microRNA-150 (miRNA/miR-150) in osteosarcoma (OS) cell invasion and metastasis by regulation Ezrin. To compare differences expression miR-150 Ezrin, models OS were established exogenous transfection on basis different levels miR-150. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) was used estimate these levels. Ezrin detected western blot assay. Methylthiazolyldiphenyl-tetrazolium bromide assay performed determine...
Cyclin D1 is aberrantly expressed in many types of cancers, including breast cancer. High levels cyclin D1b, the truncated isoform D1, have been reported to be associated with a poor prognosis for cancer patients. In present study, we used siRNA target D1b overexpression and assessed its ability suppress growth nude mice. effectively inhibited D1b. Depletion promoted apoptosis D1b‐overexpressing cells blocked their proliferation transformation phenotypes. Notably, correlated triple‐negative...
For most patients with severely ankylosed hips, traditional surgical approaches do not provide sufficient exposure during THAs. We report our experience a combined anterior and posterior approach using lateral incision for total hip arthroplasty (THA) in severe, spontaneous bony ankylosis.Between January 2004 December 2008, ankylosis underwent THA via incision.We included 47 (76 hips) mean age of 53 (range 22-72) years study. All surgeries were successful, no significant postoperative...
The objectives of this study are to investigate the clinical curative effect Gallie technique and atlantoaxial screw-rod constructs (SRC) on sagittal instability determine indication technique. Data 49 patients with from February 2008 May 2015 were analyzed retrospectively. visual analog scale (VAS) score neck disability index (NDI) used evaluate effect. Postoperative radiological outcomes stability joint bone fusion. Perioperative parameters such as blood loss, operation time, radiographic...
Abstract Giant cell tumor of bone(GCTB) is a special benign with variable aggressiveness and recurrence rate. Increasing evidences suggest that subset cells called cancer stem (CSCs) are present as cancer-initiating in range malignant tumors. However, the role CSCs such GCTB remains unknown, connection between presence biological characteristics unclear. To investigate this issue, we screened panel markers normal found ALCAM+ stromal possessed stem-like cells. Subsequently series experiments...
Study Design. Retrospective study. Objective. To determine the optimal open side in unilateral open-door laminoplasty (UODL) for lateral cervical ossification of posterior longitudinal ligament (OPLL). Summary Background Data. No literature has reported which vertebral arch should be chosen as UODL OPLL. Methods. Patients with OPLL who were treated between 2013 and 2018 retrospectively analyzed two groups: Group A, where was contralateral to ectopic bone, B, ipsilateral bone. The Japanese...
To compare proprioception recovery after anterior cruciate ligament reconstruction (ACLR) with a hamstring tendon autograft versus the artificial Ligament Advanced Reinforcement System (LARS).Forty patients (9 females, 31 males) (ACL) rupture were enrolled in this prospective study. Patients randomized to two groups, 1) ACLR using (n = 20) or 2) LARS 20). Proprioception was assessed knee joint position sense (JPS) passive-passive test at 45° and 75° flexions, contralateral healthy as control...
<b>Background</b> Anterior thoracoscopic release combined with posterior correction is a common surgery to treat idiopathic scoliosis (IS). However, whether it has detrimental effects on pulmonary function still unknown. <b>Aim</b> The aim of the study evaluate effect anterior function. <b>Materials and Methods</b> A retrospective 28 (12 male, 16 female) patients IS undergoing from 2009 2011 was performed. radiographic evaluations were performed preoperatively at 24 months postoperatively....
In the title complex, [Ag(NO(3))(C(9)H(7)N(3)OS)](n), η(1):η(1):η(1):μ(2)-bridging 2-(pyridin-4-ylsulfinyl)pyrimidine (pypmSO) ligands with opposite chiralities are alternately arranged to link Ag(I) cations through two N atoms and one sulfinyl O atom of each ligand, leading an extended zigzag coordination chain structure along [ ̅201] direction. An FT-IR spectroscopic study shows a decreased stretching frequency for η(1)-O-bonded S=O group compared that free ligand. The parallel chains...