A5109324983- Pancreatic and Hepatic Oncology Research
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Cancer Genomics and Diagnostics
- Management of metastatic bone disease
- Neuroendocrine Tumor Research Advances
- Pancreatitis Pathology and Treatment
- Natural product bioactivities and synthesis
- Inflammatory Biomarkers in Disease Prognosis
- Spine and Intervertebral Disc Pathology
- Cancer Immunotherapy and Biomarkers
- Musculoskeletal synovial abnormalities and treatments
- Bone health and treatments
- Spinal Fractures and Fixation Techniques
- Neuroblastoma Research and Treatments
- Oral and Maxillofacial Pathology
- Catalytic Alkyne Reactions
- Nausea and vomiting management
- Biological Activity of Diterpenoids and Biflavonoids
- Cancer, Lipids, and Metabolism
- Orthopedic Infections and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Catalytic C–H Functionalization Methods
- Radiomics and Machine Learning in Medical Imaging
- Gallbladder and Bile Duct Disorders
Tongji University
2025
Tongji Hospital
2022-2025
Second Military Medical University
2015-2024
Changhai Hospital
2015-2024
ShenZhen People’s Hospital
2024
Second Affiliated Hospital of Jilin University
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2023
Chongqing Medical University
2023
Gansu University of Traditional Chinese Medicine
2022
Huazhong University of Science and Technology
2022
Chordoma in the spine is relatively rare, and minimal information has been published literature regarding this subject. Moreover, there are controversies over prognostic factors of disease.A retrospective analysis chordoma was performed by survival analysis. Local relapse-free (LRFS) overall (OS) were analyzed from date surgery to local recurrence death. The LRFS OS rates estimated using Kaplan-Meier method identify potential factors. Factors with P values ≤ .1 subjected multivariate Cox...
Abstract Background About 25–37% of resectable pancreatic ductal adenocarcinoma (PDAC) had a great chance early recurrence after radical resection, which is mainly due to preoperative micrometastasis. We herein demonstrated the profiles ctDNA in PDAC and use identify patients with potential Methods A total 113 44 PDACs were enrolled discovery validation cohorts, separately. panel containing 50 genes was used screen by an NGS-based assessment high specificity. Results In cohort, overall...
A novel approach was developed for the synthesis of 2-substituted-3-functionalized benzofurans, using an intramolecular Heck reaction which further applied in first enantioselective total Daphnodorin B.
Spinal fusion is considered the gold standard procedure for treating spinal degeneration, tumors, and trauma. An inflammatory response an important part of bone repair. We investigated polarization change macrophages (M1) resident (M2) during low-intensity pulsed ultrasound (LIPUS) treatment.Thirty male Sprague Dawley rats (age: 12 weeks; weight: 300 g) were used in study. A rat model was established by surgical procedures. LIPUS treatment (20 min. d, 5 d/wk) begun 3 days after surgery. The...
Limb salvage reconstruction for pelvic tumors, especially periacetabular is challenging. We combined the use of dual mobility bearing and 3D-printed hemipelvic prosthesis to improve function reduce probability complications after hemi-pelvic resection in patients with primary acetabular malignancy. The purpose this study was evaluate efficacy safety combination.Between October 2011 May 2021, 11 malignancies involving acetabulum received replacement a bearing. Follow-up postoperative...
The study aimed to investigate the potential of tumor-stroma ratio (TSR) on digitalized whole-mount histopathology predict prognosis in patients with pancreatic ductal adenocarcinoma (PDAC). effectiveness were evaluated through internal validation. Data retrospectively collected from consecutive who underwent primary resection December 2016 August 2017 (developing cohort) and September April 2018 (validation cohort). Digitalized slide images used evaluate TSR by both pathologists a...
Goal: This study is aimed at comparing the clinical characteristics and histological types of symptomatic asymptomatic patients with heterotopic gastric mucosa in upper esophagus (HGMUE) exploring factors influencing occurrence severity laryngopharyngeal reflux (LPR) symptoms these patients. Background: HGMUE a potential cause LPR symptoms. Study: retrospective analysis evaluated 70 using detailed questionnaire. Clinical, histological, high-resolution manometry, 24-h pH impedance monitoring...
Abstract A phytochemical investigation of the branches and leaves Cephalotaxus lanceolata resulted in isolation three new cephalotaxus alkaloids, cephalancetines A, B, D ( 1, 2 , 4 resp.), together with ten known 3 5 – 13 . The structures alkaloids were elucidated on basis spectroscopic analyses, including 1D‐ 2D‐NMR, HR‐ESI‐MS, single‐crystal X‐ray diffraction. All isolated compounds tested for their cytotoxicities against four human tumor cell lines, A549, HCT116, SK‐BR‐3, HepG2. Compounds...
Gastric cancer (GC) is the most prevalent malignancy in world, especially China.GC has been postulated to spread via several different routes, including through hematogenous channels, lymphatic vessels, seeding of peritoneal surfaces, direct extension gastric wall, and retrograde vas deferens or lymphatics.Testicular metastasis rare.We show here a 53-year-old patient with GC who underwent radical total gastrectomy approximately 22 mo ago after he presented sensation heaviness swelling right...
BACKGROUND:Propofol is widely used in sedation for colonoscopy, but its adverse effects on cardiovascular and respiratory systems are still concerning. The present study investigated whether target controlled infusion (TCI) of propofol could provide a better quality than manually (MCI) training inexperienced anesthesiology residents. MATERIAL AND METHODS:Eighteen residents were allocated into 2 groups receiving TCI MCI their first month the endoscopy center, while instead second month. last...
Prostate cancer (PCa) is very common and frequently metastasizes to the spine. However, PCa spinal metastases were rarely reported in literature. In this study, outcome of therapies prognostic factors affecting surgical outcomes for patients with are discussed select best candidates aggressive resection.All affected by metastatic surgically treated at our spine tumor center reviewed. Overall survival was analyzed from time surgery. A univariate analysis a multivariate Cox proportional hazard...
Abstract Adjuvant therapy for pancreatic neuroendocrine tumors (PanNETs) after radical resection lacks evidence‐based data and remains controversial. This study aimed to validate whether long‐acting octreotide is a potential candidate adjuvant in patients with G2 PanNETs at high recurrence risk by clustering real‐world data. A retrospective review of nonmetastatic grade 2 who underwent six research centers between 2008 2020 was conducted. Propensity score matching inverse probability...
Although emerging studies have implicated that Aiopoietin-like 4 Protein (ANGPTL4) is related to the aggressiveness and metastasis of many tumors, role ANGPLT4 in giant cell tumor (GCT) bone was rarely investigated. The mechanism tumor-induced osteoclastogenesis still remains unclear. In this study, we first demonstrated ANGPTL4 highly expressed GCT compared normal tissues, while showed TGF-β2 released by osteoclasts induced resorption could increase expression GCTSCs. By using luciferase...