Alzheimer's disease (AD) is a progressive and irreversible brain degenerative disorder. Mild cognitive impairment (MCI) clinical precursor of AD. Although some treatments can delay its progression, no effective cures are available for Accurate early-stage diagnosis AD vital the prevention intervention progression. Hippocampus one first affected regions in To help diagnosis, shape volume hippocampus often measured using structural magnetic resonance imaging (MRI). However, these features...

This paper proposes a semisupervised deep neural regression network with embedding manifold (SSE-DNN) for soft sensor modeling that integrates into networks. Manifold is imposed on the hidden layer of to form network. exploits local neighbor relationship among industrial data and utilizes unlabeled effectively improve performance model. The SSE-DNN model global information large simultaneously implements implicitly multimodal models process. based applied estimation total Kjeldahl nitrogen...

In recent years, an intelligent noninvasive endoscope has been felt necessary for early diagnosis of malignant tumor in gastrointestine (GI). It is our purpose to develop a microwireless robotic examine the human GI. The presented robot's diameter and length 10 190 mm, respectively. A locomotion principle based on biomimetic earthworm adopted higher adaptability robot composed three linear driving cells. micromotor, reducer, microscrew pair mechanism are integrated into each cell....

Abstract Robotic Endovascular Intervention System (REIS) has been a focused and interesting area in robot‐assisted telesurgery. While, haptic feedback is the latest advancing study interventional robots. Few systems with are commercialized due to accuracy, instantaneity, lack of surgeon previous experience on surgery. In this article, novel force master hand controller system proposed solve problems. A SEA (Series Elastic Actuators)‐based mechanism designed provide high force/torque...

The bottleneck of the development endovascular interventional robot is that it cannot fully adapt to commercialized devices, such as guidewires, catheters, and stents, complete entire procedure treatment, for instance, stent implantation. purpose this study evaluate whether novel universal can different devices accomplish treatment peripheral vascular disease.The consists 2 components: a master surgeon console robotic platform with 4 manipulators. An adult pig was served experimental animal....

This paper proposes a new prototype of wireless micro-robot system for endoscope. The we have fabricated and tested is able to propel itself in the intestine canal pig an autonomous manner by earthworm locomotion. It different from conventional endoscope that module used communicating power transfer being up 480 mW DC receiving coil proposed system. composes communications module, personal computer, micro-robot, controller coil. experimental results show driving voltage stable which fulfils...

Abstract Background Traditional endoscopy may cause tissue trauma and discomfort to patients because of the use relatively long semi‐rigid scopes. Methods A wireless robotic endoscope has been designed based on minimally invasive locomotion techniques for energy, monitoring, telecontrol. Results The can move forward or backward effectively in a smooth synthetic glass tube. increase tube dip angle reduces relative speed. robot moves with lower efficiency viscoelasticity intestinal vitro pig...

Abstract Background Endovascular interventional surgery (EIS) is performed under a high radiation environment at the sacrifice of surgeons' health. This paper introduces novel endovascular surgical robot that aims to reduce surgeons and physical stress imposed by lead aprons during fluoroscopic X‐ray guided catheter intervention. Methods The unique mechanical structure allowed surgeon manipulate axial radial motion guide wire. Four manipulators (to wire), control console which consists four...

Non invasive micro robotic colonoscope can be applied in health care to find the malignant tumor its early stage. This project presented a novel squirm robot prototype with 13 mm diameter, 105 length, and 22.3 g weight. The is actuated by three linear motors which are composed of motor, turbine-worm, wire wrapping-sliding mechanism. actuators featured high reduce ratio small Earthworm-like locomotion principle used realize autonomous motion. Because friction difference key factor ability,...

Endovascular therapy has emerged as a crucial therapeutic method for treating vascular diseases. surgical robots have been used to enhance endovascular therapy. However, date, there are no universal that support molds of different types devices We developed novel robotic system can independently navigate the intravascular region, advance and retract devices, deploy stents. This robot four features: (1) The bionic design fully simulate entire grasping process; (2) V-shaped relay gripper...

To assess the practicability and safety of a novel endovascular robotic system for performing aortic repair in human.A prospective observational study was conducted 2021 with 6 months post-operative follow-up. Patients aneurysms clinical indications elective were enrolled study. The developed is applicable majority commercial devices various types surgeries. primary endpoint technical success without in-hospital major adverse events. Technical defined as ability to complete all procedural...

A snake changes its gait to adapt different environments. snake-like robot that is able perform as many or more gaits than a real-life has the potential successfully range of environments, similar snake. However, only few mechanisms in current framework can common gaits. In this paper, novel developed resolve problem. multi-gait established and used reference for articulation design. non-snake-like mechanism with linear combined classical swing joint. prototype designed constructed...

Robotic colonoscopy is an efficient examination method for finding malignant tumour in its early stage. This research developed a novel robotic endoscope with 13 mm diameter, 105 length and 22.3 g weight. A contact biomechanical model proposed to increase the locomotion safety efficiency soft tissue. The shows that friction difference between robot tissue key factor capability. soft, full bellow excellent compatibility was designed package body. increased static decreased kinetic given...

This paper develops a new prototype of wireless micro‐robot system for endoscopes. The we have fabricated and tested is able to propel itself in the intestine pig. Its autonomous manner earthworm‐like driven by linear actuators based on DC motor. Unlike with conventional endoscopes, that module used communicating power transfer. experimental results show driving force actuator can reach up 2.55N stable supplying 480mW receiving coil proposed system, which all fulfill need system. creep...

The snake-like robot can be adaptive to many terrains with its abundant gaits. Serpentine locomotion is adopted widely, while concertina, side winding and rectilinear motions are considered little. To improve the adaptability in non-known environment, it essential include more methods into one robot. In that case, change gaits according environment. this research, a using additional sliding joints was proposed related kinematics analysis performed. This not only realize both serpentine...

For diagnosing the colon's pathologies micro-invasively or non-invasively actively, an autonomous prototype of earthworm-like robot for colonoscopy was designed according with principle bionics and manufactured using precision process technology. In-Vitro experiments in pig colon were made. This micro drove directly by elecmagnetic linear driver. The mobile cells joined two degree-of-freedom joints whole body flexible. direction movement angle imaging can be controlled shape memory alloy...