- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Salivary Gland Disorders and Functions
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mast cells and histamine
- Spondyloarthritis Studies and Treatments
- Inflammatory Bowel Disease
- Neonatal Respiratory Health Research
- Musculoskeletal pain and rehabilitation
- Inflammasome and immune disorders
- Galectins and Cancer Biology
- Autophagy in Disease and Therapy
- Therapeutic Uses of Natural Elements
University of Rome Tor Vergata
2023-2025
Sapienza University of Rome
2021
Objective Evaluate spondyloarthritis (SpA) incidence in inflammatory bowel diseases (IBD) between patients treated with biological disease-modifying antirheumatic drugs (bDMARDs) and conventional DMARDs (cDMARDs) define risk factors associated SpA development. Methods Retrospective cohort study was conducted on Crohn’s disease (CD) or ulcerative colitis (UC) divided into two cohorts: cDMARDs bDMARDs/targeted synthetic (ts) patients. Rheumatological assessment performed presenting...
Psychological distress is commonly reported by patients affected Spondyloarthritis (SpA), with >50% experiencing concomitant depression or anxiety. This case-control study aimed to investigate the psychological dimensions of SpA assessing and comparing levels kinesiophobia, health-related quality life (HRQoL) between a healthy control (HC) group. cross-sectional included classified Assessment SpondyloArthritis international Society classification criteria group HCs matched sex age. Inclusion...
Salivary gland epithelial cells (SGECs) are key cellular drivers in the pathogenesis of primary Sjögren's syndrome (SS); however, mechanisms sustaining SGEC activation SS remain unclear. We undertook this study to determine role autophagy survival and SGECs SS.Primary isolated from minor SGs patients with or sicca were evaluated by flow cytometry, immunoblotting, immunofluorescence assess (autophagic flux, light chain 3 IIB [LC3-IIB], p62, LC3-IIB+/lysosome-associated membrane protein 1...