A5003942302- Cardiac, Anesthesia and Surgical Outcomes
- Machine Learning in Healthcare
- Artificial Intelligence in Healthcare and Education
- Acute Ischemic Stroke Management
- Cardiac Imaging and Diagnostics
- Glioma Diagnosis and Treatment
- Electronic Health Records Systems
- Animal Behavior and Reproduction
- Erythropoietin and Anemia Treatment
- Brain Metastases and Treatment
- Chronic Disease Management Strategies
- Peripheral Artery Disease Management
- Cerebral Venous Sinus Thrombosis
- Health Literacy and Information Accessibility
- Drug-Induced Ocular Toxicity
- Intracranial Aneurysms: Treatment and Complications
- Cardiac and Coronary Surgery Techniques
- Sepsis Diagnosis and Treatment
- Hypothalamic control of reproductive hormones
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Data-Driven Disease Surveillance
- Hip and Femur Fractures
- Melanoma and MAPK Pathways
- Esophageal Cancer Research and Treatment
- Frailty in Older Adults
Royal Adelaide Hospital
2024-2025
The University of Adelaide
2024-2025
SA Health
2024
Lyell McEwin Hospital
2024
Women's and Children's Health Network
2023-2024
Central Adelaide Local Health Network
2023-2024
Flinders University
2020
University of New Hampshire
2016
University Hospital Coventry
1992
Abstract Background The Adelaide Score is an artificial intelligence system that integrates objective vital signs and laboratory tests to predict likelihood of hospital discharge. Methods A prospective implementation trial was conducted at the Lyell McEwin Hospital in South Australia. added existing human, intelligence, other technological infrastructure for first 28 days April 2024 (intervention), outcomes were compared using parametric, non‐parametric health economic analyses, those 2023...
Background: The lack of availability test results in vascular surgery outpatient clinics impedes the medical management risk factors, such as dyslipidaemia and diabetes mellitus. This study sought to evaluate feasibility using computer-assisted processes promote ordering routine investigations this management. Method: After consultation with specialist clinicians, clinician-programmers developed a rule-based system facilitate lipid studies HbA1c prior clinic appointments. A four-week...
Background: Retinopathy is a common adverse event with mitogen-activated extracellular signal-regulated kinase (MEK) inhibitors. Little known about the pathophysiology of MEK inhibitor-associated retinopathy (MEKAR). Since MEKAR has many similarities to central serous chorioretinopathy (CSCR), they may share risk factors. The aim this study was evaluate association between baseline characteristics and in melanoma patients initiating inhibitor treatment. Methods: Data from treated cobimetinib...
There is little evidence to guide the perioperative management of patients on a direct oral anticoagulant (DOAC) in absence last known dose. Quantitative serum titers may be ordered, but there supporting this.This multi-center retrospective cohort study consecutive surgical in-patients with DOAC assay, performed over five-year period, aimed characterize preoperative assay orders and their impact outcomes.Patients prescribed regular (both prophylactic therapeutic dosing) were included. The...
Abstract Background The objective of this study was to evaluate the impact dysglycemia on perioperative outcomes, in patients with and without diabetes, how prior glycemic control modifies these relationships. Methods Consecutive surgical admitted six South Australian tertiary hospitals between 2017 2023 were included. Blood glucose levels within 48 h pre‐ post‐operatively assessed an adjusted analyses against a priori selected covariates. Dysglycemia metrics hyperglycemia (>10.0 mmol/L),...
There are routine hospital workflows that not addressed by certain institutional electronic medical records, including the detection of patients requiring haemodialysis who admitted under non-nephrology services. In this study, feasibility and performance a clinician-developed automated patient finder was evaluated. The programme ran with zero downtime for 6 months had false negatives or positives. This work demonstrates potential benefits may be gained when clinicians can meaningfully alter...
To evaluate the effect of a clinician-designed digital notification system on use intravenous paracetamol during medication shortage. An in-house platform was designed through multidisciplinary collaboration. A 4-week pre- and post-implementation methodology employed to intervention. There significantly lower in period compared pre-implementation (median 80 doses per day, interquartile range 58 93, vs 94, 83 122, P < .001). Multidisciplinary platforms may assist times
Abstract Background Electronic medical records (EMRs) provide multiple efficiencies in communication to clinicians. The ability copy and paste text an EMR can be useful; however, it also conveys a risk of inaccurate documentation. Studies international settings have described such overuse copying result ‘note bloat’, with the dilution relevant clinical information potential detriment. Aim To determine frequency erroneous copying, characterise component notes which this occurs performance...
Frailty, malnutrition and low socioeconomic status may mutually perpetuate each other in a self-reinforcing interdependent manner. The intertwined nature of these factors be overlooked when investigating impacts on perioperative outcomes. This study aimed to investigate the impact frailty,
Subcutaneous cerebrospinal fluid (Ommaya) reservoirs were inserted in 23 patients with acute leukaemia and 2 malignant lymphoma. In 9 used for the prophylaxis of central nervous system leukaemia: only 1 patient developed meningeal but less invasive therapy has now been shown to achieve effective prophylactic use Ommaya discontinued. 16 patients, as aids treatment or Intracranial disease was successfully controlled recurrences prevented eventually died from relapse their systemic disease. The...
A vein of Galen aneurysm occurring in a 55-year-old woman is presented. The pathogenesis and treatment this condition, which rare adults, discussed the literature reviewed.
ABSTRACT The hypothalamic-pituitary-gonadal (HPG) axis is a key biological system required for reproduction and associated sexual behaviors to occur. In the avian reproductive model of rock dove ( Columba livia ), we characterized transcript community each tissue HPG in both sexes, thereby significantly expanding our mechanistic insight into activity. We report greater sex-biased differential expression pituitary as compared hypothalamus, with multiple genes more highly expressed male being...
Background: Comprehensive resuscitation plans document treatment recommendations, such as ‘Not for cardiopulmonary resuscitation’. When created early in admission a shared decision-making process, these support patient autonomy and guide future treatment. The characteristics of patients who have documented, their timing, associations with clinical outcomes remain unclear. Objectives: To characterise factors associated plan completion, differences mortality rates Intensive Care Unit (ICU)...
<sec> <title>UNSTRUCTURED</title> N/A Would not let me proceed without entering an abstract despite this paper being a Letter to the Editor. </sec>
We read with interest the article by Cooper et al linking socioeconomic disadvantage to prevalence of antimicrobial resistance (AMR) [1].This study contributes existing knowledge regarding influence social determinants health on AMR [2].In contrast USA, Australian healthcare system consists largely public services.This was conducted evaluate generalisability observed trend in a distinct population South Australia.This retrospective cohort included all adults who had an admission greater than...