A5101409685- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pneumonia and Respiratory Infections
- MRI in cancer diagnosis
- Pediatric Hepatobiliary Diseases and Treatments
- Medical Imaging and Pathology Studies
- Mycobacterium research and diagnosis
- Dental Research and COVID-19
- Hepatitis C virus research
- SARS-CoV-2 detection and testing
- Radiomics and Machine Learning in Medical Imaging
- Appendicitis Diagnosis and Management
- Hepatitis B Virus Studies
- Advanced MRI Techniques and Applications
- Endoplasmic Reticulum Stress and Disease
- Antibiotic Use and Resistance
- Neurological Disease Mechanisms and Treatments
- Rabies epidemiology and control
- Streptococcal Infections and Treatments
- COVID-19 diagnosis using AI
- Genetic and Kidney Cyst Diseases
- Actinomycetales infections and treatment
Osaka University
2023-2024
Osaka University Hospital
2024
Hyogo Prefectural Amagasaki General Medical Center
2020-2022
Kobe University
2013-2015
Osaka Red Cross Hospital
2012-2013
Clostridium butyricum, a probiotic commonly prescribed in Asia, most notably as MIYA-BM (Miyarisan Pharmaceutical Co., Ltd.; https://www.miyarisan.com), occasionally leads to bacteremia. The prevalence and characteristics of C. butyricum bacteremia its bacteriologic genetic underpinnings remain unknown. We retrospectively investigated patients admitted Osaka University Hospital during September 2011-February 2023. Whole-genome sequencing revealed 5 (0.08%) cases among 6,576 case-patients who...
An 85‐year‐old man underwent endoscopic submucosal dissection for a large superficial esophageal epithelial neoplasm, which required removal of 95% the circumference mucosa. Steroids were given orally to prevent stricture starting on day 3 postoperatively. In 6th week steroid treatment, he developed high fever without other symptoms. Chest computed tomography revealed nodular lesion in lung. Sputum sample showed G ram‐positive, branching, filamentous bacteria, and diagnosis nocardiosis was...
Background/Objectives: COVID-19 vaccination rate among children in Japan is low. This study aimed to address the knowledge, attitudes, and practices (KAP) regarding parental vaccine acceptance hesitancy parents with infants. Methods: We conducted a paper-based, household. Survey asked status, knowledge attitudes households vaccinated child, non-vaccinated intention vaccinate child. To analyze factors associated behavior, univariate multivariate analyses were performed. Results: Response...
This study assesses the gender differences in health and anxiety, especially pertaining to mental problems time-course effects. We surveyed 121 patients admitted a hospital with COVID-19 diagnosis between March 1 August 31, 2020. Their status was evaluated on admission using Japanese General Health Questionnaire-28 (GHQ-28) State-Trait Anxiety Inventory-Form JYZ (STAI). The were divided into two groups depending period of prevalence, that is, first second waves pandemic Japan (from beginning...
Abstract The ideal approach to treat chronic hepatitis B remains controversial. This pilot study aimed evaluate the effectiveness of peginterferon (PEG‐IFN) α‐2b and entecavir hydrate (ETV) as a combination therapy for patients with B, particularly in context virological response reduction intrahepatic covalently closed circular DNA (cccDNA). A total 17 virus (HBV) genotype C were enrolled this study. All subjects treated 48 weeks observed an additional 24 weeks. underwent liver biopsy...
Corona enhancement is the visualized drainage area from a hypervascular tumor observed on single-level dynamic computed tomography during hepatic arteriography (CTHA) and thought to be high-risk for micrometastases. However, because it cannot with ordinary ultrasonography (US), we aimed visualize corona US by means of arterial injection contrast material measure its thickness. Forty-one hepatocellular carcinoma (HCC) cases were prospectively investigated. (USHA) was executed selective...
Abstract Background Recent randomized clinical trials suggest that the effect of using cetylpyridinium chloride (CPC) mouthwashes on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load in COVID-19 patients has been inconsistent. Additionally, no study investigated effectiveness on-demand aqueous chlorine dioxide mouthwash against COVID-19. Methods We performed a randomized, placebo-controlled, open-label trial to assess for any effects salivary SARS-CoV-2 among...
【目的】RFA後の治療効果判定として結節周囲に得られた凝固域の程度に応じて症例を分類し，それぞれの局所再発率を求めその意義を検討する．【方法】RVS誘導下RFAを施行した77症例99結節を対象とした．結節周囲に得られた凝固域の程度に応じて根治度（Radicality grade, R grade）を4段階（R0, R1, R2, R3）に定義した．根治度ごとの累積局所再発率を求めるとともに，局所再発に寄与する因子を解析した．また，再発症例において，再発部位における治療後腫瘍との距離を検討した．【結果】根治度別の累積局所再発率は，2年で，R3：3.7%, R2：13.6%, R1：52.6%, R0：66.7%であった．多変量解析では根治度のみが局所再発に寄与する独立した有意な因子として検出された．局所再発した25例のうち20例は，治療結節外側の凝固域が5 mm未満の部位に再発を認めた．【結論】RFAの良好な治療効果判定基準として，全周に5 mm以上の凝固域を獲得することが望まれる．
We report herein on a case of community-acquired necrotizing soft tissue infection caused by Serratia marcescens. The patient had been treated with prednisolone, tocilizumab and tacrolimus for rheumatoid arthritis. Since Gram staining the revealed negative rod bacteria, ceftriaxone clindamycin were administered as empiric therapy. Tissue culture S. Ceftriaxone was continued according to antibiotic sensitivity. She underwent debridement necrotic 17days. recovered discharged after skin grafting.
Background Gingyo-gedoku-san (GGGS) is an herbal medicine approved for upper respiratory infections in Japan. We conducted open-label, multi-center, prospective trial, comparing GGGS with oseltamivir patients influenza and influenza-like illness (ILI) as a pilot study. Methods Subjects were healthy persons aged between 16 40, enrolled from January 12, 2010 to March 24, 2011. Fifteen this trial (8 7 oseltamivir, respectively). RT-PCR was positive pandemic A (H1N1) 10 patients. The provided...
症例は21歳男性．腎炎の経過観察中に，USにて低エコー，単純CTにて高吸収を呈し，dynamic CTおよびMRIにて早期相で造影される多発結節を認めた．レボビスト造影USのpost vascular imageやSPIO MRIでは，Kuppfer細胞の存在を示唆され，USガイド下針生検では，FNH様過形成結節と診断されたが，single level dynamic CTHAにてリング様濃染を結節様高吸収域内部に認めた．周辺肝が脂肪肝を呈したため，結節血流流出部がspared areaとなり，リング様濃染部に相当する領域を含めて画像上結節様に観察されていたと考えられた．過形成結節においても，肝細胞癌に特徴的とされるリング様濃染を呈することがあると考えられ報告した．
Abstract Background Antimicrobial therapy with appropriate biliary drainage is considered the standard of care for acute cholangitis, but optimal duration antimicrobial remains unknown. Seven to 10 days are common treatment a recent retrospective cohort study suggested shorter might be effective. A can beneficial in decreasing length hospital stay, improving patients’ quality life, adverse effects, and even contributing decrease occurrence resistance. Methods/design We will conduct...
Correspondence and reprint request: Ryuichi Kita, M.D., Ph.D. Department of Gastroenterology Hepatology, Osaka Red Cross Hospital. 5-53 Fudegasaki-cho, Tennoji-ku, 543-8555. Telephone: +81-6-6774-5111. Fax: +81-6-6774-5131. E-mail: r-kita@osaka-med.jrc.or.jp Manuscript received:November 24, 2011. accepted: December 14,2011. July-August, Vol. 11 No.4, 2012: 572-573 LETTER TO EDITOR
肝細胞癌に対するラジオ波熱凝固療法では，十分なablative marginを得て凝固することが重要であり，その評価は通常CTで行われる．今回，当院でRFAを行った連続70結節に造影CTとソナゾイド®造影超音波を用いてablative marginに関する4段階の治療効果判定（R判定）を行い，結果を比較した．R判定の完全一致率は50%，重み付きκ係数は0.49であったが，再治療要不要判定の一致率は73%と高く，概ねCTと同等の評価が可能であった．また，造影超音波では16結節（26.2%）で凝固域内に腫瘍影が同定できた．この群では，造影CTで腫瘍にリピオドール®集積を認めた群とのR判定の完全一致率は70%，重み付きκ係数は0.75と高値であり，リピオドール®動注の下での造影CTと同程度のablative marginの評価が可能であった．以上より，ソナゾイド®造影超音波は，良好な画像が得られた場合，再治療要不要の判定に，凝固域内に腫瘍影が同定できた例でのablative marginの治療効果判定に有用であると言えた．
Corona enhancements on single level dynamic CTHA (sCTHA) images are thought to be characteristic of hypervascular metastatic liver tumors and HCCs. Herein we present two cases (an FNH a nodule-in-nodule type HCC) in which sCTHA showed corona enhancements. In the literature, venous sinusoidal drainage pathways have been confirmed histopathologically FNH. We presume that flow occurs mainly through hepatic pathway via is faint may visible only when amount becomes large followed by an increase...
Most recent modalities for diagnosing hepatic tumors are based on evaluation of the arterial and portal flow tumors. However, pseudo-lesions resulting from A-P shunting, aberrant circulation splancnic veins may occur, which often make it difficult to reach a definitive diagnosis. Real-time virtual ultrasonography, however, presents cross-section reconstructed CT data. This modality has proven be very useful detection lesions find with usual methods. With this modality, we could identify...
Mouthwashes containing cetylpyridinium chloride (CPC) or on-demand aqueous chlorine dioxide (ACD) have potential to reduce the salivary severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) load in individuals with SARS-CoV-2 infection. This study will evaluate effect of CPC and ACD mouthwashes on levels asymptomatic mild infection (COVID-19) staying a residential recuperation facility Osaka, Japan. randomized, open-label clinical trial include three equal-sized groups (CPC mouthwash,...