A5017352054- Pancreatic and Hepatic Oncology Research
- Pancreatitis Pathology and Treatment
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Neuroendocrine Tumor Research Advances
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- IgG4-Related and Inflammatory Diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Biliary and Gastrointestinal Fistulas
- Cancer Immunotherapy and Biomarkers
- Gastrointestinal Tumor Research and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Neuroblastoma Research and Treatments
- Body Composition Measurement Techniques
- Lung Cancer Research Studies
- Metastasis and carcinoma case studies
- Gut microbiota and health
- Hepatitis B Virus Studies
- Helicobacter pylori-related gastroenterology studies
- Cancer Diagnosis and Treatment
- Eosinophilic Esophagitis
Hyogo University
2022-2025
Kobe Medical Center
2025
Hyogo Medical University
2021-2024
Kobe University
2015-2024
The Japanese Society of Gastroenterological Surgery
2024
Iwate Medical University
2024
Onomichi General Hospital
2024
Hiroshima University
2024
National Institute of Diabetes and Digestive and Kidney Diseases
2023
ProQuest (United States)
2023
Background Differentiation between multicentric Castleman's disease and systemic immunoglobulin (Ig) G4-related lymphadenopathy is sometimes difficult. It has been suggested that measurement of the IgG4-/IgG-positive cell ratio useful for differential diagnosis two diseases. However, authors present a detailed report six patients with abundant IgG4-positive cells (IgG4-/IgG-positive ratio, >40%). Results In series, showed lymphadenopathy, polyclonal hypergammaglobulinaemia elevated serum...
Metabolomics provides data about all the metabolic processes of a cell or organism. So far, changes that occur in levels metabolites during development colitis have not been fully elucidated. Here we examined metabolite serum and colon tissue mice using gas chromatography mass spectrometry (GC/MS) with aim achieving detailed understanding pathogenesis inflammatory bowel disease (IBD). To induce colitis, C57BL/6J were administered 3.0% dextran sulfate sodium (DSS) their drinking water for 5...
Endoscopic ultrasound-guided biliary drainage (EUS-BD) can be carried out by two different approaches: choledochoduodenostomy (CDS) and hepaticogastrostomy (HGS). We compared the efficacy safety of these approaches in malignant distal obstruction (MDBO) patients using a prospective, randomized clinical trial.Patients with after failed endoscopic retrograde cholangiopancreatography were randomly selected for either CDS or HGS. The procedures at nine tertiary centers from September 2013 to...
Goals The predictors of malignant intraductal papillary mucinous neoplasm (IPMN) and invasive IPMN were investigated in this study to determine the optimal indicators surgical resection for IPMN. Background Recently, international consensus guidelines have described standard However, IPMN, especially branch duct still remain controversial. Study Eighty-two patients with who underwent during April 1998 January 2009, retrospectively reviewed examined regard their preoperative factors...
ABSTRACT Citrobacter rodentium , a murine model pathogen for enteropathogenic Escherichia coli colonizes the surface of intestinal epithelial cells and causes mucosal inflammation. This bacterium is an ideal investigating pathogen-host immune interactions in gut. It well known that gene transcripts Th1 cytokines are highly induced colonic tissue from mice infected with C. . However, it remains to be seen whether or Th2 produced by antigen-specific CD4 + T provide effective regulation host...
Objectives No comprehensive study has examined short‐ and long‐term adverse outcomes of endoscopic ultrasound (EUS)‐guided treatment pancreatic fluid collections (PFCs) including walled‐off necrosis (WON) pseudocysts. Methods In a multi‐institutional cohort 357 patients receiving EUS‐guided PFCs (228 with WON 129 pseudocysts), we PFC type‐specific risk factors for procedure‐related events (AEs), clinical failure, recurrence. Odds ratios (ORs) hazard (HRs) 95% confidence intervals (CIs) were...
Abstract Background With the increasing popularity of endoscopic ultrasound (EUS)-guided transmural interventions, walled-off necrosis (WON) pancreas is increasingly managed via non-surgical interventions. However, there has been an ongoing debate over appropriate treatment strategy following initial EUS-guided drainage. Direct necrosectomy (DEN) removes intracavity necrotic tissue, potentially facilitating early resolution WON, but may associate with a high rate adverse events. Given safety...
Abstract Background Immune checkpoint inhibitor-related pancreatic injury (ICI-PI) is a rare occurrence, which has not been reported in detail. We conducted retrospective multicenter study to determine the clinical characteristics, risk factors, and treatment of ICI-PI. Methods reviewed medical records patients who received ICIs for malignant tumors between April 2014 2019 at 16 participating hospitals. Patients with elevated enzymes or pancreatitis were identified classified using Common...
Focal parenchymal atrophy and main pancreatic duct (MPD) dilatation have been identified as early signs of ductal adenocarcinoma. However, limited evidence exists regarding their temporal progression due to previous study limitations with restricted case numbers.
Endoscopic papillectomy (EP) for benign ampullary neoplasms could be a less-invasive alternative to pancreatoduodenectomy (PD). There are some problems and limitations with EP. The post-EP resection margins of tumors often positive or uncertain because the burning effect clinical outcomes resected margin cases after EP remain unknown.To investigate EP.Between January 2007 October 2018, all patients who underwent at Kobe University Hospital were included in this study. indications as follows:...
Objective Stenting is an established endoscopic therapy for malignant gastric outlet obstruction (mGOO). The choice of stent (covered vs uncovered) has been examined in prior randomised studies without clear results. Design In a multicentre prospective study, we compared covered (CSEMS) with uncovered self-expandable metal stents (UCSEMS) patients mGOO; main outcomes were dysfunction and patient survival, subgroup analyses extrinsic intrinsic tumours. Results Overall survival was poor no...