- Meta-analysis and systematic reviews
- Semiconductor materials and devices
- Lung Cancer Treatments and Mutations
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Intensive Care Unit Cognitive Disorders
- Semiconductor materials and interfaces
- Pleural and Pulmonary Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pneumonia and Respiratory Infections
- Delphi Technique in Research
- Lung Cancer Diagnosis and Treatment
- Occupational and environmental lung diseases
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Clinical practice guidelines implementation
- Integrated Circuits and Semiconductor Failure Analysis
- Cardiac, Anesthesia and Surgical Outcomes
- Artificial Intelligence in Healthcare and Education
- Dialysis and Renal Disease Management
- Ultrasound in Clinical Applications
- Cancer Immunotherapy and Biomarkers
- Silicon and Solar Cell Technologies
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Research Studies
Kyoto Min-iren Asukai Hospital
2020-2025
Kyoto University
2016-2025
Scientific Research WorkS Peer Support Group
2021-2025
Santen (Japan)
2020-2025
Tohoku University
2025
Hosei University
2025
Hyogo Prefectural Amagasaki General Medical Center
2015-2024
Fukui Prefectural Hospital
2024
Hiroshima University Hospital
2020-2024
Gunma University
2024
Few studies have delineated the real-world, long-term trends of prescription patterns antidepressants for patients with major depressive disorder (MDD). This study aims to describe their vicissitudes in nationally representative sample US from 1996 2015 and explore characteristics. We used Medical Expenditure Panel Survey, a database population, between 2015. estimated prevalence MDD among adults, calculated proportions those on antidepressant treatment as well specific drugs through two...
Recently, the creation of new heterogeneous catalysts using unique electronic/geometric structures small metal nanoclusters (NCs) has received considerable attention. However, to achieve this, it is extremely important establish methods remove ligands from ligand-protected NCs while preventing aggregation NCs. In this study, ligand-desorption process during calcination was followed for metal-oxide-supported 2-phenylethanethiolate-protected gold (Au) 25-atom five experimental techniques. The...
Flk-1 (human counterpart, KDR) tyrosine kinase, which is one of the two VEGF receptors, crucial for vascular development. Recently, we showed that, among residues KDR, 1175 (Y1175, corresponding to Y1173 in murine Flk-1) and Y1214 (Y1212 are autophosphorylated response VEGF, that Y1175 important VEGF-dependent phospholipase Cγ/PKC/mitogen-activated protein kinase activation leading DNA synthesis cultured endothelial cells. However, importance these Flk-1/KDR vivo not yet known. To examine...
Mesenchyme Fork Head-1 (MFH-1) is a forkhead (also called winged helix) transcription factor defined by common 100-amino acid DNA-binding domain. MFH-1 expressed in non-notochordal mesoderm the prospective trunk region and cephalic neural-crest mesoderm-derived mesenchymal cells prechordal of early embryos. Subsequently, strong expression localized developing cartilaginous tissues, kidney dorsal aortas. To investigate developmental roles during embryogenesis, mice lacking locus were...
Several phospholipase C (PLC) isoforms have been found in male and female mammalian gametes, splicing of PLCdelta4 are predominantly expressed testis. Here we report that mice which the gene had disrupted either produced few small litters or were sterile. In vitro fertilization studies showed insemination with PLCdelta4-/- sperm resulted significantly fewer eggs becoming activated calcium transients associated absent delayed. unable to initiate acrosome reaction, an exocytotic event required...
Various studies on functionalization of water-splitting photocatalysts have been performed toward their practical usage. Control the cocatalyst has investigated, and recently, in addition to particle-size control, alloying extensively used achieve this goal. It is essential investigate with precisely controlled cocatalysts obtain a detailed understanding effect heteroatom doping photocatalytic activity thereby establish clear design guidelines for functionalization. However, previous...
This study demonstrates that controlling intra-cluster ligand interactions is important to obtain an assembled structure with the desired connecting structures.
To investigate whether and when the correction is done in Systematic Reviews (SRs) Clinical Practice Guidelines (CPGs) included Randomized Controlled Trials (RCTs) have been retracted.In this meta-epidemiological study, we SRs CPGs citing retracted RCTs from Retraction Watch Database. We investigated how often were cited CPGs. also such corrected themselves.We identified 587 articles (525 62 CPGs) RCTs. Among articles, 252 (43%) published after retraction, 335 (57%) before retraction. 127...
Amifostine is an important drug in the new field of cytoprotection. It was developed by Antiradiation Drug Development Program US Army Medical Research and Command as a radioprotective compound first from that to be approved for clinical use protection dose limiting normal tissues patients against damaging effects radiation chemotherapy. Its unique polyamine-like structure attached sulfhydryl group give it potential participate range cellular processes make exciting candidate both...