Edoardo G. Ostinelli

ORCID: 0000-0002-8717-0832
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About
Contact & Profiles
Research Areas
  • Mental Health Research Topics
  • Schizophrenia research and treatment
  • Treatment of Major Depression
  • Mental Health Treatment and Access
  • Bipolar Disorder and Treatment
  • Digital Mental Health Interventions
  • Attention Deficit Hyperactivity Disorder
  • Tryptophan and brain disorders
  • Sleep and related disorders
  • Resilience and Mental Health
  • Sleep and Wakefulness Research
  • Neurotransmitter Receptor Influence on Behavior
  • Posttraumatic Stress Disorder Research
  • COVID-19 and Mental Health
  • Telemedicine and Telehealth Implementation
  • Healthcare Decision-Making and Restraints
  • Meta-analysis and systematic reviews
  • Functional Brain Connectivity Studies
  • Child and Adolescent Psychosocial and Emotional Development
  • Circadian rhythm and melatonin
  • Health, Environment, Cognitive Aging
  • Pharmacovigilance and Adverse Drug Reactions
  • Health Systems, Economic Evaluations, Quality of Life
  • Electroconvulsive Therapy Studies
  • Health Policy Implementation Science

Oxford BioMedica (United Kingdom)
2021-2025

University of Oxford
2020-2025

Oxford Health NHS Foundation Trust
2020-2025

Warneford Hospital
2020-2025

National Institute for Health Research
2022-2025

National Health Service
2021-2025

University of Milan
2013-2022

University of Tokyo Hospital
2021

Vanderbilt University
2021

Kyoto University
2021

Mental disorders frequently begin in childhood or adolescence. Psychotropic medications have various indications for the treatment of mental dis-orders this age group and are used not infrequently off-label. However, adverse effects these require special attention during developmentally sensitive periods life. For meta-review, we systematically searched network meta-analyses randomized controlled trials (RCTs), individual RCTs, cohort studies reporting on 78 a priori selected events across...

10.1002/wps.20765 article EN World Psychiatry 2020-05-11

Few studies have delineated the real-world, long-term trends of prescription patterns antidepressants for patients with major depressive disorder (MDD). This study aims to describe their vicissitudes in nationally representative sample US from 1996 2015 and explore characteristics. We used Medical Expenditure Panel Survey, a database population, between 2015. estimated prevalence MDD among adults, calculated proportions those on antidepressant treatment as well specific drugs through two...

10.3389/fpsyt.2020.00035 article EN cc-by Frontiers in Psychiatry 2020-02-14

The coronavirus disease (COVID-19) presents unique challenges in health care, including mental care provision. Telepsychiatry can provide an alternative to face-to-face assessment and also be used creatively with other technologies enhance but clinicians patients may feel underconfident about embracing this new way of working.The aim paper is produce open-access, easy-to-consult, reliable source information guidance telepsychiatry COVID-19 using evidence-based approach.We systematically...

10.2196/21108 article EN cc-by JMIR Mental Health 2020-07-10

Top‐tier evidence on the safety/tolerability of 80 medications in children/adolescents with mental disorders has recently been reviewed this jour­nal. To guide clinical practice, such data must be combined efficacy and acceptability. Besides medications, psychosocial inter­ventions brain stimulation techniques are treatment options for disorders. For umbrella review, we systematically searched network meta‐analyses (NMAs) (MAs) randomized controlled trials (RCTs) evaluating 48 20...

10.1002/wps.20881 article EN World Psychiatry 2021-05-18

Background The COVID-19 pandemic required mental health services around the world to adapt quickly new restrictions and regulations put in place reduce risk of transmission. As face-to-face contact became difficult, virtual methods were implemented continue safely provide care. However, it is unclear what extent service provision transitioned telemental worldwide. Objective We aimed systematically review global research literature on how adapted during first year pandemic. Methods searched...

10.2196/38600 article EN cc-by JMIR Mental Health 2022-07-21

Background International guidelines present overall symptom severity as the key dimension for clinical characterisation of major depressive disorder (MDD). However, differences may reside within levels related to how symptoms interact in an individual patient, called dynamics. Aims To investigate these by estimating proportion patients that display their dynamics while sharing same severity. Method Participants with MDD ( n = 73; mean age 34.6 years, s.d. 13.1; 56.2% female) rated baseline...

10.1192/bjp.2024.19 article EN cc-by The British Journal of Psychiatry 2024-04-08

Background Digital approaches may be helpful in augmenting care to address unmet mental health needs, particularly for schizophrenia and severe illness (SMI). Objective An international multidisciplinary group was convened reach a consensus on the challenges potential solutions regarding collecting data, delivering treatment, ethical digital SMI. Methods The development panel method used, with an in-person meeting of 2 groups: expert panel. Membership including those lived experience, equal...

10.2196/57155 article EN cc-by JMIR Mental Health 2024-05-08

<ns3:p>Background Exercise for post-traumatic stress disorder (PTSD) is a potentially effective adjunct to psychotherapy. However, the biopsychosocial mechanisms of exercise are not well understood. This co-produced living systematic review synthesizes evidence from human and non-human studies. Methods We Included controlled studies involving searches multiple electronic databases (until 31.10.23). Records were screened, extracted, assessed risk bias, reconciled by two independent reviewers....

10.12688/wellcomeopenres.23033.2 preprint EN cc-by Wellcome Open Research 2025-02-05

<ns3:p>Background Exercise for post-traumatic stress disorder (PTSD) is a potentially effective adjunct to psychotherapy. However, the biopsychosocial mechanisms of exercise are not well understood. This co-produced living systematic review synthesizes evidence from human and non-human studies. Methods We Included controlled studies involving searches multiple electronic databases (until 31.10.23). Records were screened, extracted, assessed risk bias, reconciled by two independent reviewers....

10.12688/wellcomeopenres.23033.3 preprint EN cc-by Wellcome Open Research 2025-04-07

For many years, long-acting intramuscular (LAI) antipsychotics have been prescribed predominantly to chronic and severe patients, as a last resort when other treatments failed. Recently, broader earlier use of LAIs, particularly second-generation has emphasized. To date, few studies attempted frame how this change in prescribing took place real-world practice. Therefore, study aimed describe the clinical features patients with explore possible differences between first- second-generations...

10.1371/journal.pone.0201371 article EN cc-by PLoS ONE 2018-08-02
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