A5002983016- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Spondyloarthritis Studies and Treatments
- Vasculitis and related conditions
- COVID-19 Clinical Research Studies
- Autoimmune and Inflammatory Disorders Research
- Renal Diseases and Glomerulopathies
- SARS-CoV-2 and COVID-19 Research
- Sarcoidosis and Beryllium Toxicity Research
- Tuberculosis Research and Epidemiology
- Viral Infections and Immunology Research
- Ocular Diseases and Behçet’s Syndrome
- Dermatological and COVID-19 studies
- Psoriasis: Treatment and Pathogenesis
- Drug-Induced Ocular Toxicity
- Lipid metabolism and disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Urticaria and Related Conditions
- Hidradenitis Suppurativa and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Otitis Media and Relapsing Polychondritis
- Oral Health Pathology and Treatment
- Pregnancy and Medication Impact
- Reproductive System and Pregnancy
- Kawasaki Disease and Coronary Complications
Manipal Hospital
2014-2023
Bhagwan Mahaveer Jain Hospital
2022
JSS Medical College and Hospital
2022
Fortis Hospital
2022
Creative Commons
2022
Apollo Hospitals
2022
Aster Medcity
2022
Yenepoya University
2022
SDM College of Medical Science and Hospital
2022
Sparsh Hospital
2022
Abstract Aim Tuberculosis ( TB ) is one of the major adverse events concern associated with use biologics for managing autoimmune inflammatory rheumatic diseases AIRD s). The study presents data on incidence in relation to biologic used, screening test and prophylaxis a real‐world setting. Methods cross‐sectional, observational, retrospective was conducted across 12 centres Karnataka, India. included patients receiving therapy s, established based respective diagnostic criteria. development...
Introduction Identifying factors predicting adverse pregnancy outcomes involving systemic lupus erythematosus (SLE) is a research priority. The aims of this study were to investigate (a) the maternal and fetal pregnant patients associated with outcomes, (b) effect on disease activity these patients. Methods This was an ambi-directional collecting information from five multi-specialist referral centres across state Karnataka, India over 5 years (2013–2018). Clinical details pregnancies that...
Abstract Background We conducted this study to identify the influence of prolonged use hydroxychloroquine (HCQ), glucocorticoids and other immunosuppressants (IS) on occurrence outcome COVID-19 in patients with autoimmune rheumatic diseases (AIRDs). Methods This was a prospective, multicenter, non-interventional longitudinal across 15 specialist rheumatology centers. Consecutive AIRD treatment were recruited followed up longitudinally assess parameters contributing development its outcome....
Cutaneous polyarteritis nodosa (CPAN) is a distinct clinical entity represented by chronic, relapsing, benign course, with rare systemic involvement. Treatment CSs, CYC or other conventional synthetic DMARDs (csDMARDs). In this case series, we aimed to share our varied experience of successfully treating patients CPAN, tofacitinib in refractory/relapsing course as upfront monotherapy without CSs/csDMARDs.We report retrospective series managed at rheumatology centre Bangalore from 2019 2022....
Adalimumab is a well-established anti-tumor necrosis factor therapy for patients with ankylosing spondylitis (AS). An indigenously developed biosimilar adalimumab (bADA) (ZRC-3197; Exemptia) approved prescribing in India. In this article, we present the effectiveness and tolerability of bADA real-life Indian AS from Biosimilar Patient Registry (ASPIRE) (ISRCTN: 16838474).ASPIRE postmarketing observational registry evaluating real-world experiences autoimmune inflammatory disorders across...
Introduction: Biologics are widely used in Autoimmune rheumatologic diseases (AIRDs), however the need to capture real life data which monitors indications, adverse reactions cannot be over emphasized. Methods: This is a cross-sectional ambidirectional multi-center study conducted 8 months from January 2016 August 2016, across 12 tertiary care rheumatology centers Karnataka, India by members of Karnataka Rheumatology Association. Results: The most common biologic prescribed tumour necrosis...
Abstract Introduction We assessed the risk factors and outcome of COVID-19 in patients with autoimmune rheumatic diseases(AIRD) who contracted infection while on background treatment tofacitinib. Methods This is a non-interventional, cross-sectional, questionnaire based telephonic study which included consecutive AIRD tofacitinib co-treatment. Data related to subset, disease modifying anti drugs(DMARDs) including glucocorticoids comorbidities, was collected from 7 rheumatology centers across...
The TNF-α blocker adalimumab is a well-proven therapy for rheumatoid arthritis (RA). A biosimilar (ZRC-3197; Exemptia™), 'fingerprint match' to reference adalimumab, has been approved prescription in India since 2014. Here, we report on the effectiveness and tolerability of this (bADA) from Adalimumab Biosimilar Patient Registry [ASPIRE; ISRCTN16838474], which contains data real-life RA patients India. ASPIRE post-marketing, observational registry that evaluates real-world experience across...
Introduction: Comorbidities frequently accompany psoriasis and psoriatic arthritis (PsA) add to the disease burden. We aimed identify comorbidity burden in patients with PsA evaluate its impact on activity measures our geographic region. Methods: This was a multicenter, cross-sectional study involving consecutive from 17 rheumatology centers. Their variables comorbidities were recorded. Results: In 549 enrolled patients, mean age 39.2 (14.9) years, male predominance (6:5). The duration of...
<h3>Background:</h3> Majority of the Sarcoid series are from Pulmonology centers rather than Rheumatology centers. The ACCESS study quoted commonly in review articles and text books has been described This multicentric was undertaken to enumerate clinical, radiological pathological aspects patients Sarcoidosis presenting OPD <h3>Objectives:</h3> To describe Clinical, Radiological manifestations <h3>Methods:</h3> It is a Retro-prospective cross sectional descriptive 17 Karnataka, South India....
Systemic Lupus Erythematosus (SLE) warrants an early diagnosis and prompt management. Delay in can result repeated flares, permanent damage, even death. There is a large variability the time taken to diagnose SLE across world. We undertook this study determine for of India identify factors associated.
Patients with SLE (systemic lupus erythematosus) have a higher risk of infection due to dysregulated immune system as well long-term use immunosuppressants (IS). This could influence the COVID-19 and its outcome.We conducted longitudinal prospective study across 15 rheumatology centres during first wave pandemic understand factors contributing in patients. During 6 months follow-up, those who tested positive for COVID-19, their clinical course outcome information were recorded.Through period...
Abstract Pyoderma gangrenosum (PG) is a rare autoinflammatory disorder falling under the spectrum of neutrophilic dermatosis, characterized by distinctive skin ulceration which non‐infective, non‐neoplastic and usually with no primary vasculitis. PG lesions are notorious for relapse hence require multiple trials medications often prolonged concomitant use steroids. Due to lack evidence‐based studies on effective treatment options PG, we have presented three isolated biopsy‐proven cases who...
Background: Biologics have been the focus of recent treatment guidelines and ‘Treat to Target’ strategies for both psoriasis (PsO) & psoriatic Arthritis (PsA). However, in day-today practice, combination DMARDs anchored around methotrexate are mainstay majority patients. Objectives: To describe experience effectiveness Methotrexate with conventional Karnataka Psoriatic Cohort. Methods: Treatment information was extracted from KPsAC (n=549) which is a cross sectional, non-interventional...
Background: Clinical patterns and disease burden of PsA varies in different parts the world. Demographic studies from Indian subcontinent are sparse Objectives: To study cutaneous, articular profile describe their activity, disability co-morbidities (CMs) Methods: This is a multicenter, cross-sectional, non-interventional Karnataka, India. All consecutive patients defined by CASPAR or expert diagnosis were evaluated over 8 months 17 Rheumatology centers across Karnataka using standard...
Introduction: Psoriatic arthritis (PsA) is a chronic inflammatory disease with significant functional impairment. Health Assessment Questionnaire-Disability Index (HAQ-DI) reliable and validated outcome measure for variety of arthritides including PsA. Objective: The objective this study was to assess the disability as an in PsA using Indian version HAQ (I-HAQ). Methods: I-HAQ administered patients diagnosed per Classification Criteria comprises 12 questions (nine basic three advanced...
Abstract Background We conducted this study to identify the influence of prolonged use hydroxychloroquine(HCQ), glucocorticoids (GC) and other immunosuppressants (IS) on occurrence outcome COVID-19 in patients with autoimmune rheumatic diseases (AIRDs). Methods This was a prospective, multicenter, non-interventional longitudinal across 15 specialist rheumatology centers. Consecutive AIRD treatment were recruited followed up longitudinally assess parameters contributing development its...
Focal segmental glomerulosclerosis (FSGS) is the histologic end point of many disease processes that affect kidney. Clinically, adults with FSGS present proteinuria may be accompanied by nephrotic syndrome. Once identifiable (secondary) causes are excluded, diagnosis idiopathic FSGS, a challenging glomerular to understand and manage, made. On basis mostly retrospective data, first-line treatment for patients nephrotic-range prolonged course corticosteroids. However, steroid resistance common...
<h3>Background</h3> Renal involvement occurs in 40-70% of SLE patients. Biopsy is performed to look for the class lupus nephritis. <h3>Objectives</h3> We describe clinicopathological and treatment outcomes ten cases podocytic lesions. <h3>Methods</h3> A retrospective evaluation 10,482 native renal biopsies referred our institute during period Jan 2010-Dec 2014 revealed 710 (6.8%) nephritis (LN). Distinct with biopsy proven LN lesions formed current case-series. Detailed clinical, lab...
Granulomatosis with polyangiitis (GPA) is an autoimmune granulomatous disease of unknown etiology; frequently associated anti-proteinase 3 antineutrophil cytoplasmic antibody (PR3-ANCA). Although any organ can be involved, prostatic involvement in GPA very rare. We present a male patient GPA, 26 years old, pulmonary manifestations and who underwent exhaustive evaluation. The patient's laboratory tests imaging scans showed evidence lesions multiple areas, including the prostate....