A5085732343- Malaria Research and Control
- Mosquito-borne diseases and control
- Insect Resistance and Genetics
- Viral Infections and Vectors
- Insect Pest Control Strategies
- Dengue and Mosquito Control Research
- Species Distribution and Climate Change
- Disaster Response and Management
- Seed Germination and Physiology
- Allelopathy and phytotoxic interactions
- Digital Imaging for Blood Diseases
- Plant Parasitism and Resistance
- Viral Infections and Outbreaks Research
- Iron Metabolism and Disorders
Nigerian Institute of Medical Research
2018-2025
Ladoke Akintola University of Technology
2023
University of Lagos
2019-2021
Anopheles gambiae, An. coluzzii and arabiensis are the three major vectors of malaria in Nigeria. These mosquitoes have developed resistance to different insecticides. Insecticides intensity assay was recently introduced provide insight into potential operational significance insecticide resistance. Here, we present data on pyrethroids mechanisms from six vector surveillance sites (Lagos, Ogun, Edo, Anambra, Kwara Niger) Adult reared larval collections were tested using WHO insecticides...
The need for evidence-based data, to inform policy decisions on malaria vector control interventions in Nigeria, necessitated the establishment of mosquito surveillance sites a few States Nigeria. In order make evidence-based-decisions, predictive studies using available data becomes imperative. We therefore predict distribution major members Anopheles gambiae s.l. Immature stages were collected from 72 study locations which span throughout year 2020 resulted identification over 60,000...
The ecology and biology of mosquito disease vectors the genus Aedes are highly dynamic, adapting to various climatic topographic factors which makes their control challenging. Evidence-based mosquitoes requires a detailed understanding this adaptability, is greatly influenced by environmental dynamics. Understanding drivers distribution hence pertinent predict risk. To better understand dynamics, we studied in Lagos State, Nigeria, its connection human factors. larvae adults were collected...
In Nigeria, most research and malaria vector control efforts have focused on primary vectors within the Anopheles gambiae complex, with less emphasis other secondary vectors. Consequently, understudied demonstrated a proportional increasing role in transmission. This study utilized geospatial models to understand potential distribution of anopheline species than An . complex (non- species) Nigeria. Adult mosquitoes were sampled monthly between 2020 2022, concurrent surveys larval sites...
Pyrethroids and DDT are key insecticides in the control of malaria, yellow fever, lymphatic filariasis vectors. Knockdown metabolic resistance mechanisms have been proven to be important determining efficacy insecticides. Here we investigated cytochrome P450 as a mechanism Anopheles gambiae Giles Culex quinquefasciatus Say exposed deltamethrin DDT. Two- three-days-old adult female mosquitoes were used for insecticide exposures PBO synergistic assays using WHO standard guidelines, kits test...
Information on native mosquito species viz-a-vis the nature of their breeding sites can help determine epidemiology mosquito-borne diseases in an environment, hence, were surveyed Suleja metropolis. All accessible larval habitats between June and October, 2023 within township New (Sabo) Gwazunu both which are A total five species: An. gambiae s.l, Cx. quinquefasciatus, Aedes albopictus, aegypti, papiens encountered. The mean values larvae recovered from transient habits such as rock holes...
Abstract Background Aedes aegypti transmits several arboviral diseases of global public health threat such as dengue, zika, and yellow fever. Recently, a series fever outbreaks have been reported in different parts the country. Globally, control mosquito-borne has relied heavily on insecticides based vector efforts. Therefore, we assessed susceptibility status to three classes WHO approved evaluated importance detoxifying enzymes resistance collected from Lagos State, Nigeria. immature...
Abstract The outbreak of yellow fever virus transmitted by Aedes aegypti has been major concern in Nigeria, this mosquito also transmits several other arboviruses globally. control many vectors mosquito-borne diseases relies heavily on the use insecticides. Therefore, constant monitoring insecticide resistance status and associated mechanisms is crucial within local population. Here, we determined profile adult Ae. from Majidun Oke Ota communities, Ikorodu Local Government Area Lagos State,...
Allelopathy has gained much attention in recent times the sustainable agricultural systems. Allelochemicals released by different plants interact differently with each other, it therefore becomes imperative to study possible biochemical processes underlying allelopathy of some on other plants. In present study, investigation was carried out phytochemical composition aqueous and methanolic extracts <em>Tithonia diversifolia</em> their allelopathic effect growth <em>Vigna...
The development of insecticide resistance in different species mosquitoes to Pyrethroids is a major challenge for vector-borne diseases transmitted by mosquitoes. Failure control would impact negatively on the gains recorded mosquito-borne previous years. In anticipation country-wide deployment Pyrethroid-treated nets Nigeria, this study assessed susceptibility Culex quinquefasciatus Say. (Diptera: Culicidae) Owhelogbo, Ejeme and Oria-Abraka communities Delta State, Niger-Delta, Nigeria....
Background: Anopheles gambiae mosquitoes are one of the best-known genus because their predominant role in transmitting most dangerous malaria parasite species (to humans), Plasmodium falciparum. Unfortunately, An. have grown resistant to popular and widely used insecticides, particularly Permethrin, spreading across Africa. The current study sought determine lowest Permethrin concentrations that could be a selection pressure for metabolic resistance development renowned adult (Kisumu)...
Background: Insecticide resistance in Anopheles gambiae s.l. is a major challenge for malaria vector control Nigeria. Both target-site insensitivity and metabolic have been im-plicated process, with the latter receiving little attention Therefore, we investigated enzyme activities s.l populations resistant to Del-tamethrin Diethyldichlorotriethylethane (DDT) South-West Methods: larvae were collected from Ibadan, Oyo Badagry, Lagos. Adults exposed Deltamethrin DDT using WHO method. Cohorts of...
Background: Culex mosquitoes are important vectors of several human pathogens causing infections such as lymphatic filariasis and viruses. Poor blocked drainage system can lead to impediment in water flow, leading the artificial creation larval habitats for mosquitoes. has ability breed organically polluted bodies exhibit high resistance insecticides. Therefore, this study assessed species insecticides susceptibility status breeding drainages Lagos State. Methods: mosquito larvae were...
The outbreak of yellow fever transmitted by Aedes aegypti has been major concern in Nigeria, this mosquito also transmits several other arboviruses globally. control many the borne diseases relies heavily on use insecticides. Therefore, constant monitoring insecticide resistance status and associated mechanisms crucial within local population. Here, we determined profile adult from Ikorodu Local Government Area Lagos State, Nigeria to different classes insecticides using WHO procedures....
In view of recent findings that codon 1575 mutation increases the L1014F-mediated resistance in Anopheles mosquitoes, we investigated presence this four States with intense pyrethroid Nigeria. Permethrin and deltamethrin susceptibility tests were carried out using 2–3 day old adult female from larval collections. Based on test results, intensity 5x 10x concentrations at sites high (% mortality>85). Resistant specimen identified by PCR screened for L1014F N1575Y mutations allele specific...
Entomological data gathering is essential for monitoring malaria vector disease risks and selection of appropriate interventions the protection exposed human populations. This study assessed relative abundance, species composition, sporozoite infection rates indoor resting An. gambiae s.l. vectors in six communities across 3 Local Government Areas Kwara State, Nigeria. Total number mosquitoes collected by Pyrethrum Spray Catch method over a period eighth months were correlated with rainfall...
Malaria vector abundance has been linked to certain agricultural practices. This work examined the impact of practice irrigation on composition and seasonal distribution malaria vectors in agrarian communities Kano state. Longitudinal data collection was done four times a year, corresponding different transmission seasons from early rains late rainy season, dry season season. Indoor-biting adult mosquitoes were collected using standard pyrethrum spray (PSC) techniques. Female Anopheles...
Mosquito survey and identification are foundational elements of an effective vector management plan. The present study therefore aimed to collect identify various mosquito species in some selected Area Councils the Federal Capital Territory (FCT), Nigeria. Larval mosquitoes were collected identified difference breeding sites across councils FCT. larvae raised adult stage further using morphological key. Data obtained analysed SPSS version 27.0 p-value was set at 95%. Samples from Abuja...
Enzymes mediated resistance development and their activities are well documented in Anopheles gambiae vectors. However, biological consequences of such malaria vectors obscure. The present study aims to determine the implications response An. (Kisumu) population following exposure a concentration Permethrin selection pressure across multiple generations. Adult Kisumu mosquitoes exposed 0.2 µg/ CDC bottle over generations were compared with unexposed control populations by way status, cost...
Abstract Malaria vector surveillance is required to determine disease transmission dynamics, insecticide susceptibility status, suitable control strategies and impact of interventions. However, capacity resources for resistance monitoring often inadequate in most countries at risk vector-borne diseases. Collaborations linkages between malaria policy makers existing research institutions generating data are weak, thereby hindering the availability decision-making. A national programme,...
The prevalence and risks of malaria depend on Anopheles vectorial capacity which includes the vector’s density, contact with humans longevity. Therefore, this study was conducted to investigate species density Man-Biting Rate in three riverine communities Taraba State, north-east Nigeria. Monthly sampling indoor mosquitoes done between September, 2015 August 2017 Ardo Kola, Bali Donga using Pyrethrum-Spray Catch (PSC), taking note number persons that slept overnight sampled-rooms size rooms....
To identify the specific Anopheles mosquito sibling species responsible for malaria transmission, determine their vectorial potential, and predict suitable control measures, this study investigated genetic identities, human blood feeding, sporozoite infection rates of endophilic mosquitoes in Gaa-Bolorunduro, a cattle rearing community Kwara State, Nigeria.Monthly pyrethrum spray collections were conducted one year addition to PCR characterization ELISA probing meal infections. Mean numbers...
Studies profiling community and zonal malaria entomological risk indices are required to identify high areas where targeted control resources most needed or likely have the greatest impact on reducing of infection. This study presents a first report vector in two vegetation zones within Adamawa state, Nigeria. Endophilic mosquitoes were collected for one year selected communities Guinea Sudan savanna State. Plasmodium falciparum Sporozoite human blood meal ELISA assays carried out female...