A5100568451- Plant Stress Responses and Tolerance
- Intraperitoneal and Appendiceal Malignancies
- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Plant Molecular Biology Research
- Neuroendocrine Tumor Research Advances
- Cancer-related gene regulation
- Advanced Measurement and Detection Methods
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Lipids, and Metabolism
- Plant Reproductive Biology
- Ferroptosis and cancer prognosis
- Geotechnical Engineering and Soil Stabilization
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal Tumor Research and Treatment
- Vascular Malformations and Hemangiomas
- Lung Cancer Treatments and Mutations
- Grouting, Rheology, and Soil Mechanics
- RNA modifications and cancer
- Peroxisome Proliferator-Activated Receptors
- Mosquito-borne diseases and control
- Genetic diversity and population structure
- Conducting polymers and applications
- Metabolomics and Mass Spectrometry Studies
- Slime Mold and Myxomycetes Research
State Administration of Traditional Chinese Medicine of the People's Republic of China
2023-2025
Southern Medical University
2023-2025
Beijing Shijitan Hospital
2024-2025
Capital Medical University
2024-2025
Ocean University of China
2023-2024
Northwest Institute of Mechanical and Electrical Engineering
2024
Sichuan Academy Of Social Sciences
2023-2024
Jiangsu Province Hospital
2022-2023
Nanjing Medical University
2022-2023
Shandong Special Equipment Inspection Institute
2023
Abstract On 5 September 2022, an Mw 6.6 strike-slip earthquake occurred in Luding, Sichuan, China. It illuminates the seismic gap on southern end of Xianshuihe fault zone, that is Moxi segment, and most damaging Chinese Mainland since 2014. In this article, we use multiple seismological methods to analyze basic characteristics Luding earthquake, including its source parameters, rupture process, aftershock distribution, further discuss implications preseismic behavior impact short-term...
Lipid metabolism plays an important role in the occurrence and development of cancer, particular, digestive system tumors such as colon cancer. Here, we investigated fatty acid-binding protein 5 (FABP5) colorectal cancer (CRC). We observed marked down-regulation FABP5 CRC. Data from functional assays revealed inhibitory effects on cell proliferation, colony formation, migration, invasion well tumor growth vivo. In terms mechanistic insights, interacted with acid synthase (FASN) activated...
Abstract N6‐methyladenosine modification, especially Wilms tumor 1‐associated protein (WTAP), is reportedly associated with a variety of cancers, including colorectal cancer (CRC). Angiogenesis also plays an important role in the occurrence and development CRC. However, only few studies have reported biological mechanisms underlying this connection. Therefore, tissue microarray public database were used to explore WTAP levels Then, was down‐regulated over‐expressed, respectively. CCK8, EdU,...
Pancreatic neuroendocrine neoplasms (pNENs) are among the most frequently occurring (NENs) and require targeted therapy. High levels of fatty acid binding protein 5 (FABP5) involved in tumor progression, but its role pNENs remains unclear. We investigated mRNA FABP5 pNEN tissues cell lines found them to be upregulated. evaluated changes proliferation using CCK-8, colony formation, 5-ethynyl-2'-deoxyuridine assays examined effects on migration invasion transwell assays. that knockdown...
Abstract The process of post-transcriptional regulation has been recognized to be significantly impacted by the presence N 6-methyladenosine (m6A) modification. As an m6A demethylase, ALKBH5 shown contribute progression different cancers increasing expression several oncogenes. Hence, a better understanding key targets in cancer cells could potentially lead development new therapeutic targets. However, specific role pancreatic neuroendocrine neoplasms (pNENs) remains largely unknown. Here,...
Malignant peritoneal mesothelioma (MPM) is a rare but aggressive cancer. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) was the preferred choice for selected patients. The purpose of this study to thoroughly examine impact combined treatment prognostic variables, particularly neutrophil-to-lymphocyte ratio (NLR). Characteristics MPM patients who underwent CRS HIPEC treatment, followed by adjuvant were retrospectively collected. univariable analysis...
Siberian wildrye (Elymus sibiricus L.), a model Elymus Gramineae plant, has high eco-economic value but limited seed and forage yield. TCP transcription factors are widely regarded as influencing yield quality being crucial for growth development; still, this gene family in remains unexplored. Therefore, study looked at the family's reaction to several abiotic stresses, its expression pattern, potential evolutionary path. Fifty-four members of EsTCP were discovered. There two major...
Elymus nutans Griseb. (Poaceae: Triticeae, 2n=6x=42) is a dominant perennial plant species in the Qinghai-Tibetan Plateau China, which an important forage resource high-altitude and cold regions most popular used for high yield artificial grassland planting because of its rich nutritional value good palatability herbivorous ruminant animals. In this study, using advanced sequencing technology, we generated allohexaploid reference genome E. nutans, representing three sets chromosomes...
Drought is one of the most important factors affecting plant growth and production due to ongoing global climate change. Elymus sibiricus has been widely applied for ecological restoration reseeding degraded grassland in Qinghai-Tibetan Plateau (QTP) because its strong adaptability barren, salted, drought soils. To explore mechanism resistance E. sibiricus, drought-tolerant drought-sensitive genotypes were used metabolomic studies under simulated long-term short-term stress. A total 1091...
Abstract Background Encephalitis caused by dengue virus (DENV) is considered a manifestation of severe dengue. Tanreqing injection (TRQ) well-known Chinese patented medicine, which has been used to treat brain-related disorders inhibiting inflammation. Nevertheless, the effects TRQ on DENV encephalitis have not studied. The aim this study was evaluate and explore its potential mechanisms. Methods cytotoxicity examined MTT assay, anti-DENV activities in BHK-21 baby hamster kidney fibroblast...
Abstract Objectives Pancreatic cancer with peritoneal metastasis presents a challenging prognosis, limited effective treatment options available. This study aims to evaluate the efficacy and safety of combining cytoreductive surgery (CRS) hyperthermic intraperitoneal chemotherapy (HIPEC) as strategy for this patient group. Methods A retrospective analysis was conducted on patients pancreatic who underwent CRS + HIPEC at Beijing Shijitan Hospital from March 2017 December 2023. The focused...
Orchardgrass (Dactylis glomerata L.) is highly tolerant of shade, cold, and overwintering, making it an ideal species for grassland ecological restoration livestock production. However, the genetic diversity orchardgrass may be threatened by climate change. Using a Maximum Entropy (MaxEnt) model with BCC-CSM2-MR global database Harmonized World Soil Database, we projected current future distribution suitable areas globally. The predicted thresholds vital environmental factors were determined...
Kengyilia is a newly established genus. Most species in this genus survive hash environment, which might be an indicator of acquirement stress resistance genes and the potential for molecular breeding Triticeae species. Quantitative real-time PCR (qRT-PCR) widely used technique with varied sensitivity heavily dependent on optimal level reference genes. K. melanthera typical psammophyte has high drought resistance. The are not yet reported. This study aims to evaluate expression stability 14...
Background:Orlistat is an antiobesity drug approved by the US Food and Drug Administration (FDA) with potential antitumor activity against a few malignant tumors, however, whether orlistat affects progression of pancreatic neuroendocrine tumors (pNETs) remains unknown.Methods: Protein mRNA levels FASN were measured using western blotting (WB) qRT-PCR.The effects on cell proliferation examined CCK-8, colony formation, EdU assays.The migration invasion tested transwell assay.A lipid...