A5102823979- Virus-based gene therapy research
- RNA Interference and Gene Delivery
- Signaling Pathways in Disease
- Engineering Technology and Methodologies
- Additive Manufacturing Materials and Processes
- Calpain Protease Function and Regulation
- Cell Adhesion Molecules Research
- Aluminum Alloy Microstructure Properties
- Monoclonal and Polyclonal Antibodies Research
- Digestive system and related health
- Immune Response and Inflammation
- Face and Expression Recognition
- Aluminum Alloys Composites Properties
- Advanced Neural Network Applications
- Computer Graphics and Visualization Techniques
- Molecular Biology Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Soil Mechanics and Vehicle Dynamics
- Cytokine Signaling Pathways and Interactions
- Educational Research and Pedagogy
- Neuropeptides and Animal Physiology
- Influenza Virus Research Studies
- Video Surveillance and Tracking Methods
- Corrosion Behavior and Inhibition
- Osteoarthritis Treatment and Mechanisms
Shanxi Medical University
2022-2025
Beijing Technology and Business University
2024
University of Science and Technology Beijing
2024
Jiangnan University
2023
Shanghai Jiao Tong University
2022
Ruijin Hospital
2022
Chinese Academy of Sciences
2018-2019
Changchun Institute of Applied Chemistry
2018-2019
China Agricultural University
2016
Shandong University
2013
The FSH-FSHR pathway has been considered an essential regulator in reproductive development and fertility. But there emerging evidence of FSHR expression extragonadal organs. This poses new questions long-term debates regarding the physiological role FSH-FSHR, underscores need for reliable, vivo analysis animal models. However, conventional methods have proven insufficient examining due to several limitations. To address this challenge, we developed Fshr-ZsGreen reporter mice under control...
The interactions between ground reaction forces and inter-unit coupling add complexity to the study of turning motion articulated tracked vehicles (ATVs). To accurately analyze performance an ATV, this developed a steady-state steering model that captures effects load transfer caused by centrifugal forces. First, based on vehicle kinematics under skidding conditions, formulas incorporate parameters for lateral track displacement were derived calculate radii front rear units. Then, traction...
The opioid inactive isomer (+)-naltrexone is one of the rare Toll-like receptor 4 (TLR4) antagonists with good blood–brain barrier (BBB) permeability, which a lead promising potential for treating neuropathic pain and drug addiction. (+)-Naltrexone targets lipopolysaccharides (LPS) binding pocket myeloid differentiation protein 2 (MD-2) blocks innate immune TLR4 signaling. However, details molecular interactions its derivatives MD-2 are not fully understood, hinders ligand-based discovery....
Behavior is an important indicator reflecting the welfare of animals. Manual analysis video most commonly used method to study animal behavior. However, this approach tedious and depends on a subjective judgment analysts. There urgent need for automatic identification individual animals tracking fundamental part solution problem. In study, algorithm based Hybrid Support Vector Machine (HSVM) was developed automated laying hens in layer group. More than 500 h conducted with raised under floor...
The Cre/lox system is a fundamental tool for functional genomic studies, and number of Cre lines have been generated to target genes interest spatially temporally in defined cells or tissues; this approach has greatly expanded our knowledge gene functions. However, the limitations recently recognized, we must address challenge so-called nonspecific/off-target effects when line utilized investigate interest. For example, cathepsin K (Ctsk) used as specific osteoclast marker, driven by its...
CpG ODNs demonstrate a significant promise for immunotherapy. However, their application is limited owing to quick DNase digestion and inadequate cellular internalization. Transportation of into immune cells crucial. Although viral vectors exhibit high transfection efficiency, safety risks, cost, low carrying capacity remain big obstacles. Herein, novel vector was fabricated by using starch. Starch ultrasonicated simply aminated (NH2–St) through grafting with diethylenetriamine, which...
Motion planning algorithms for unmanned tracked vehicles (UTV) which travel on off-road terrain often suffer from low accuracy and poor robustness when confronted with track sliding factor. SSTP-RRT (Slope-Steering Trajectory Parameter-space Rapidly-exploring Random Tree) motion algorithm is proposed the slope-steering of UTV while considering A modified vehicle mechanical model established to describe process steering slope. The considers combined horizontal vertical as well centrifugal...
<title>Abstract</title> Addressing the issues of incomplete detection instance targets, challengesin detecting occluded objects, and segmentation in complex scenesusing diffusion models for multi-target segmentation, this paper introduces Pixel DiffusionSeg, an approach based on multi-leveldeformable attention models. This method leverages benefitsof deformable self-attention, which adaptively adjusts receptive field size,incorporating it into proposed framework. Additionally, aggregates...
This paper proposes a novel hardware-accelerating deformation algorithm based on curve-skeleton model for 2D shape manipulation. The can achieve real-time interactive manipulation without any pre-computing step. deforming regions of shapes are demarcated with simple skeleton frame and simulated by consisting triangle-strips. obtains two properties that smooth flexion preservation area. Smooth is guaranteed due to the continuous derivative curve function, area achieved via adjusting...