A5106547078- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Eosinophilic Disorders and Syndromes
- Acute Lymphoblastic Leukemia research
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Gastrointestinal Tumor Research and Treatment
- Cardiac Arrest and Resuscitation
- Lung Cancer Treatments and Mutations
- Lymphoma Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Platelet Disorders and Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Eosinophilic Esophagitis
- Viral-associated cancers and disorders
- Sports Performance and Training
- Bioactive Compounds in Plants
- Healthcare and Venom Research
- HER2/EGFR in Cancer Research
- Autoimmune and Inflammatory Disorders Research
- Gastrointestinal Bleeding Diagnosis and Treatment
- Fungal Plant Pathogen Control
- Exercise and Physiological Responses
- Alcohol Consumption and Health Effects
Catholic University of Korea
2012-2024
Seoul St. Mary's Hospital
2010-2024
Ewha Womans University
2022
Woosuk University
2021
Kyung Hee University
2017
Bank of Korea
2017
Hanyang University Medical Center
2016
Chonnam National University Hwasun Hospital
2010-2014
Inha University
2008
Although recent studies have suggested that cessation of imatinib (IM) in chronic myeloid leukemia patients can be associated with sustained response, further validation is needed to explore predictive factors. In a prospective, multicenter study, phase were eligible for IM therapy after more than 3 years if they had no detectable BCR-ABL1 transcript at least 2 years. A total 48 median age 47 (19-74 years) enrolled. Twenty received post-transplant relapse. After follow-up 15.8 months...
Although imatinib is considered as a front line therapy in patients with chronic myeloid leukemia (CML), it still unclear whether transient discontinuation may adversely affect the outcome. This study was conducted to investigate long-term outcome after and resumption of imatinib, determine intermittent can be employed CML. Twenty six Philadelphia chromosome positive (Ph+) CML discontinued when they achieved complete cytogenetic response (CCyR) or molecular (CMR), were retreated case...
Abstract Aims Sodium-glucose cotransporter-2 inhibitors (SGLT2is) have been shown to improve cardiovascular outcomes and reduce the incidence of atrial fibrillation (AF) in patients with type 2 diabetes mellitus (T2DM). We investigated clinical without use SGLT2is T2DM concomitant AF. Methods results derived patient data from a warehouse constructed electronic medical records seven centres. Data for 11 012 diagnosed both AF were analysed. New SGLT2i users classified into group those who not...
The aim of this study was to estimate the prognostic factors for outcomes chronic myeloid leukemia (CML) patients receiving allogeneic stem cell transplantation (SCT) in phase (CP) era tyrosine kinase inhibitors (TKIs). Ninety-seven who underwent SCT CP were analyzed. Forty-seven TKI-naïve at time transplant, and 50 received TKI(s) treatment before transplantation. After a median follow-up 115.8 months, 4-year overall survival event-free 80.4 58.8%, respectively. Multivariate analysis showed...
BACKGROUND: Ankle or knee joint cooling has shown to increase muscle activation in controlled laboratory measurements. OBJECTIVE: To examine if a bilateral 20-min lower-extremity alters maximal vertical jump heights over time. METHODS: Twenty-one healthy male basketball and volleyball players participated this cross study. One of three conditions was assigned for each session (ankle cooling, control). Subjects performed jumps with (countermovement jump: CMJ) without (squat SJ) using...
Abstract We analysed the dynamic change of imatinib‐resistant mutations in BCR‐ABL kinase domain focusing on T315I mutation during dasatinib or nilotinib therapy. Fifty‐five chronic myeloid leukaemia patients (32 with and 23 without mutation) different disease phases were treated (median 17.3 months) 6.8 months). Among 32 baseline mutation, including M244V, G250E, E255K, M351T, H396R, S417Y, E450K E459K disappeared 8 new detected 9 patients, all which T315I. 4 showed newly developed T315I, +...
We conducted this study to identify the factors for predicting poor outcomes in chronic myeloid leukemia patients who failed achieve a 3-month early molecular response (EMR). Of 413 newly diagnosed, phase, receiving imatinib (IM), 120 (29.1%) EMR. With median follow-up of 67.0 months, 39 continued IM treatment with at least complete cytogenetic (CCyR), and 81 permanently discontinued treatment. The cumulative incidence rates CCyR major (MMR) by 3 years were 90.1 ± 3.9% 53.7 7.3%,...
Abstract The present study aimed to assess the clinical impact of BCR ‐ ABL 1 transcript levels determined at an earlier time point than 3‐month early molecular response ( EMR ) in chronic‐phase chronic myeloid leukemia CML CP patients. patients (n = 258; median age, 43 [range, 18‐81] years) treated with various tyrosine kinase inhibitors TKI s) were 4 weeks (28 ± 3 days) and every months treatment initiation. At weeks, receiver operating characteristic curves revealed that cutoff values...
옥수수수염, 율무, 표고버섯 그리고 사과껍질 70% 주정 추출물들(CS, JT, LE, AP)은 항산화 활성이 있었고, 그것 중에 CS가 총폴리페놀 함량, 플라보노이드 DPPH 라디칼 소거작용, ABTS 소거작용 환원력과 같은 효과가 가장 높았다. 지방분화는 CS, AP 사과껍질을 함유한 개발 빵 추출물(DB)을 각각 처리한 3T3-L1 지방세포에서 연구하였다. DB1과 DB2는 지방 전구세포 분화 억제 및 있었다. 중성지방 축적은 실험한 시료들(CS, AP) 중에서 분화된 TG 축적을 억제하였고 3T3-L1에서 지방분화와 관련된 인자들을 조절하였다. CS는 세포에서 지방구 형성과 지방세포 분화를 농도 의존적으로 억제하였다. 지방분화 동안 다양한 농도(10, 50, 100 ㎍/mL)에서 CS와 함께 C/EBPβ, PPARγ aP2 mRNA와 단백질 수준에 대한 CS의 영향력을 실험하였고, 지방세포에 CS 처리는 PPARγ와 mRNA 발현을 감소시켰다. 역시 지방분화중에...
The invasion of Cydalima perspectalis (Walker, 1859) (Lepidoptera, Crambidae) poses a significant threat to European ecosystems and North American ornamentals. In an effort identify potential biological control agents from the native habitats C. , field survey was conducted 2022 2024 in South Korea. During survey, new braconid agathidine species Braunsia Kriechbaumer, 1894 discovered: hodorii Kang, sp. nov. is delimited described based on morphological, molecular, phylogenetic data....