Samantha Terhorst

ORCID: 0009-0005-5727-4218
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About
Contact & Profiles
Research Areas
  • Cardiovascular Disease and Adiposity
  • Cancer, Stress, Anesthesia, and Immune Response
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cancer, Lipids, and Metabolism
  • Inflammatory Biomarkers in Disease Prognosis
  • Diet and metabolism studies
  • Nanopore and Nanochannel Transport Studies
  • Adipose Tissue and Metabolism
  • Extracellular vesicles in disease
  • Immune cells in cancer
  • Membrane Separation Technologies

The Ohio State University Wexner Medical Center
2020-2024

The Ohio State University
2020-2024

The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute
2023

Obesity is a risk factor for pancreatic ductal adenocarcinoma (PDAC), deadly disease with limited preventive strategies. Lifestyle interventions to decrease obesity represent potential approach prevent obesity-associated PDAC. In this study, we examined whether decreasing through physical activity (PA) and/or dietary changes could inflammation in humans and PDAC mice. Comparison of circulating inflammatory-associated cytokines subjects (overweight obese) before after PA intervention revealed...

10.1158/0008-5472.can-23-1045 article EN Cancer Research 2024-05-22

<div>Abstract<p>Obesity is a risk factor for pancreatic ductal adenocarcinoma (PDAC), deadly disease with limited preventive strategies. Lifestyle interventions to decrease obesity represent potential approach prevent obesity-associated PDAC. In this study, we examined whether decreasing through physical activity (PA) and/or dietary changes could inflammation in humans and PDAC mice. Comparison of circulating inflammatory-associated cytokines subjects (overweight obese) before...

10.1158/0008-5472.c.7451282.v1 preprint EN 2024-09-16

Obesity is a risk factor for pancreatic ductal adenocarcinoma (PDAC), deadly disease with limited preventive strategies. Lifestyle interventions to decrease obesity might prevent obesity-associated PDAC. Here, we examined whether decreasing by increased physical activity (PA) and/or dietary changes would inflammation in humans and PDAC mice.

10.1101/2023.01.03.521203 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-01-04

Objectives Endoscopic pancreatic function tests are used to diagnose diseases and a viable source for the discovery of biomarkers better characterize disorders. However, fluid (PF) contains active enzymes that degrade biomolecules. Therefore, we tested how preservation methods time storage influence integrity quality proteins nucleic acids. Methods We obtained PF from 9 subjects who underwent an endoscopic test. Samples were snap frozen at collection; after 1, 2, 4 hours on ice; or overnight...

10.1097/mpa.0000000000001717 article EN Pancreas 2020-12-16

<div>Abstract<p>Obesity is a risk factor for pancreatic ductal adenocarcinoma (PDAC), deadly disease with limited preventive strategies. Lifestyle interventions to decrease obesity represent potential approach prevent obesity-associated PDAC. In this study, we examined whether decreasing through physical activity (PA) and/or dietary changes could inflammation in humans and PDAC mice. Comparison of circulating inflammatory-associated cytokines subjects (overweight obese) before...

10.1158/0008-5472.c.7451282 preprint EN 2024-09-16

Abstract Background: Obesity is a risk factor for pancreatic ductal adenocarcinoma (PDAC), deadly disease with no preventive strategies. Lifestyle interventions to decrease obesity might serve prevent obesity-induced PDAC. We examined whether decreasing via increased physical activity (PA) and/or diet-induced weight loss could PDAC in mice and compared the levels of systemic inflammatory-associated cytokines human subjects undergoing PA intervention. Methods: Obesity-induced mouse models...

10.1158/1538-7445.panca20-po-034 article EN Cancer Research 2020-11-13
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