A5115806590- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Olfactory and Sensory Function Studies
- Diabetes Treatment and Management
- Computational Drug Discovery Methods
- Drug-Induced Ocular Toxicity
- Pharmacovigilance and Adverse Drug Reactions
- Advanced Breast Cancer Therapies
- Pharmacology and Obesity Treatment
- Receptor Mechanisms and Signaling
- Neurological Disorders and Treatments
- Retinal and Optic Conditions
- Psoriasis: Treatment and Pathogenesis
- Estrogen and related hormone effects
- Inflammatory mediators and NSAID effects
Xiamen University
2024-2025
Chongqing Three Gorges University
2025
Eye Center
2024
Background Dry eye syndrome (DES) has become a significant public health issue, impacting quality of life. Meibomian Gland Dysfunction (MGD) is primary contributor to DES, and its etiology includes diverse factors. Given the potential for drug-induced MGD, comprehensive investigation into this association crucial.
Objective Although numerous drugs have been associated with cataracts, the risk for most remains unclear. This study aimed to investigate factors drug-induced cataracts by analyzing large-scale data from U.S. Food and Drug Administration Adverse Event Reporting System (FAERS). Methods We used reporting odds ratio (ROR) evaluate reports of in FAERS first quarter 2004 third 2024. A univariate analysis, LASSO (least absolute shrinkage selection operator) regression, a multivariate regression...
This study aimed to evaluate the risk of drug-related dry eye using real-world data, underscoring significance tracing pharmacological etiology for distinct clinical types eye. Analyzing adverse event reports in Food and Drug Administration Adverse Event Reporting System (FAERS) from January 2004 September 2023, we employed disproportionality analysis Bayesian confidence propagation neural network algorithm. The involved categorizing drugs causing eye, assessing levels, conducting segmental...
This study evaluates the risk of ocular adverse events (AEs) associated with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) by analyzing data from FDA Adverse Event Reporting System (FAERS) and employing network pharmacology methods.
As prostaglandin medications, crucial in glaucoma treatment, become more widely used, their local adverse events are increasingly observed.
<title>Abstract</title> <bold>Objective:</bold> Dry Eye Syndrome (DES) poses a growing public health concern, significantly impacting quality of life. Among its various causes, Meibomian Gland Dysfunction (MGD) plays pivotal role. This study focuses on investigating drug-induced MGD to enhance drug safety assessment. <bold>Methods: </bold>We analyzed FDA Adverse Event Reporting System (FAERS) data from January 2004 September 2023. Using statistical methods like the Ratio Odds Ratios (ROR)...
Aromatase inhibitors (AIs) are commonly used to treat postmenopausal hormone receptor positive breast cancer, but there is currently a lack of comprehensive safety reports on AIs in large-scale cohorts.