A5022014016- Immune cells in cancer
- Immune Response and Inflammation
- Telomeres, Telomerase, and Senescence
- Mitochondrial Function and Pathology
- Genetic Neurodegenerative Diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Tryptophan and brain disorders
- Toxin Mechanisms and Immunotoxins
- Peptidase Inhibition and Analysis
- Signaling Pathways in Disease
- Cancer, Stress, Anesthesia, and Immune Response
- Cancer Cells and Metastasis
- Antibiotic Resistance in Bacteria
- Cancer Research and Treatments
- Cassava research and cyanide
- Muscle Physiology and Disorders
- Plant biochemistry and biosynthesis
- Epigenetics and DNA Methylation
- Cancer Genomics and Diagnostics
- Ubiquitin and proteasome pathways
- Extremum Seeking Control Systems
- Infections and bacterial resistance
- Advanced Control Systems Design
- Single-cell and spatial transcriptomics
Institute of Genomics and Integrative Biology
2021-2024
Tata Institute of Fundamental Research
2024
Academy of Scientific and Innovative Research
2024
National Centre for Biological Sciences
2024
Baylor College of Medicine
2024
Guru Nanak Dev University
2021
University of Delhi
2015-2020
Abstract Peptidyl-prolyl cis–trans isomerases (PPIases) are the only class of enzymes capable isomerization prolyl peptide bond. The PPIases, comprising different families viz., cyclophilins, FK506-binding proteins (FKBPs), parvulins and protein phosphatase 2A activators (PTPAs), play essential roles in cellular processes. Though PPIase gene have been characterized organisms, information regarding these is lacking Penicillium species, which commercially an important fungi group. In this...
Telomeres are crucial for cancer progression. Immune signalling in the tumour microenvironment has been shown to be very important prognosis. However, mechanisms by which telomeres might affect immune response remain poorly understood. Here, we observed that interleukin-1 is telomere-length dependent cells. Mechanistically, non-telomeric TRF2 (Telomeric Repeat binding Factor 2) at IL-1-receptor type-1 (IL1R1) promoter was found affected telomere length. Enhanced IL1R1 cells with short...
Abstract Racial disparities in triple-negative breast cancer (TNBC) outcomes have been reported. However, the biological mechanisms underlying these remain unclear. We integrated imaging mass cytometry and spatial transcriptomics, to characterize tumor microenvironment (TME) of African American (AA) European (EA) patients with TNBC. The TME AA was characterized by interactions between endothelial cells, macrophages, mesenchymal-like which were associated poor patient survival. In contrast,...
Telomeres are crucial for cancer progression. Immune signalling in the tumour microenvironment has been shown to be very important prognosis. However, mechanisms by which telomeres might affect immune response remain poorly understood. Here, we observed that interleukin-1 is telomere-length dependent cells. Mechanistically, non-telomeric TRF2 (Telomeric Repeat binding Factor 2) at IL-1-receptor type-1 (IL1R1) promoter was found affected telomere length. Enhanced IL1R1 cells with short...
Telomeres are crucial for cancer progression. Immune signalling in the tumour microenvironment has been shown to be very important prognosis. However, mechanisms by which telomeres might affect immune response remain poorly understood. Here, we observed that interleukin-1 is telomere-length dependent cells. Mechanistically, non-telomeric TRF2 (telomeric repeat binding factor 2) at IL-1-receptor type-1 (IL1R1) promoter was found affected telomere length. Enhanced IL1R1 cells with short...
Telomeres are crucial for cancer progression. Immune signalling in the tumour microenvironment has been shown to be very important prognosis. However, mechanisms by which telomeres might affect immune response remain poorly understood. Here, we observed that interleukin-1 is telomere-length dependent cells. Mechanistically, non-telomeric TRF2 (telomeric repeat binding factor 2) at IL-1-receptor type-1 (IL1R1) promoter was found affected telomere length. Enhanced IL1R1 cells with short...
Abstract Telomeres are crucial for cancer progression. Immune signalling in the tumour microenvironment has been shown to be very important prognosis. However, mechanisms by which telomeres might affect immune response remain poorly understood. Here, we observed that interleukin-1 is telomere-length dependent cells. Mechanistically, non-telomeric TRF2 (Telomeric Repeat binding Factor 2) at IL-1-receptor type-1 (IL1R1) promoter was found affected telomere length. Enhanced IL1R1 cells with...
One of the utmost challenge in conventional control engineering is to gratify glitches, which are categorized by numerous objectives. In modern system, monitoring and physically altering operating conditions a dynamical system has been done using an efficient controller achieve consistent, governable steady system. PID (Proportional-Integral-Derivative) controllers have used because their strong performance enhancement applications basic three parameters i.e. proportional gain, integral gain...