David T. Ramsey

ORCID: 0009-0005-8411-7357
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About
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Research Areas
  • melanin and skin pigmentation
  • Corneal surgery and disorders
  • Corneal Surgery and Treatments
  • Glaucoma and retinal disorders
  • Ocular Disorders and Treatments
  • Ocular Oncology and Treatments
  • Intraocular Surgery and Lenses
  • Rabies epidemiology and control
  • Veterinary Equine Medical Research
  • Coccidia and coccidiosis research
  • Cutaneous lymphoproliferative disorders research
  • Connexins and lens biology
  • Ocular Surface and Contact Lens
  • Retinal Development and Disorders
  • Cardiovascular Conditions and Treatments
  • Vascular Tumors and Angiosarcomas
  • Livestock and Poultry Management
  • Barrier Structure and Function Studies
  • Venomous Animal Envenomation and Studies
  • Veterinary Oncology Research
  • Tendon Structure and Treatment
  • T-cell and Retrovirus Studies
  • Facial Rejuvenation and Surgery Techniques
  • Otitis Media and Relapsing Polychondritis
  • Renal Diseases and Glomerulopathies

Williams (United States)
2011-2023

Michigan United
2014

Ophthalmology Clinic
2011

Michigan State University
1997-2008

New York University
1983-2006

University of Illinois Urbana-Champaign
1994-2000

Aurora Optics (United States)
1999

Carl Zeiss (Germany)
1999

Alcon (United States)
1999

MSPCA-Angell
1996

SUMMARY The effects of 3 occlusive dressing materials and a standard, nonadherent material on healing full-thickness skin defects were evaluated in dogs. Two wounds measuring 2 × cm created bilaterally (4 wounds/dog) the dorsolateral aspect trunk 12 Beagles. Wound treatments evenly distributed between 4 sites, using Latin square design. Treatments were: equine amnion (group A), biosynthetic hydrogel B), transparent polyethylene sheeting T), semiocclusive rayon/polyethylene, C). Rates...

10.2460/ajvr.1995.56.07.941 article EN American Journal of Veterinary Research 1995-07-01

To compare corneal thickness, intraocular pressure, and optical diameter in Rocky Mountain Horses with cornea globosa those clinically normal corneas.129 Horses.Ultrasonic pachymetry was used to measure thickness. Applanation tonometry pressure. A Jameson caliper diameter.The central temporal peripheral portions of the were significantly thicker horses than corneas, but thicknesses dorsal, ventral, medial not different between groups. There no differences thickness male female or right left...

10.2460/ajvr.1999.60.10.1317 article EN American Journal of Veterinary Research 1999-10-01

Abstract Objective —To determine corneal thickness, intraocular pressure (IOP), and horizontal vertical diameter (HCD VCD) to obtain axial measurements of the anterior chamber depth (ACD), crystalline lens thickness (CLT), vitreous (VtCD), globe length (AGL) in eyes Miniature Horses. Animals —41 healthy Procedure —Ocular component were obtained via ultrasonic pachymetry, applanation tonometry, ultrasound, by use a Jameson caliper. Results —Mean IOP for all 26.0 mm Hg 785.6 µm, respectively....

10.2460/ajvr.2003.64.661 article EN American Journal of Veterinary Research 2003-06-01

To determine density of corneal endothelial cells and thickness in eyes euthanatized horses.52 normal from 26 horses.Eyes were enucleated after horses euthanatized. Eyes examined to that they did not have visible ocular defects. Noncontact specular microscopy was used cells. Corneal measured, using ultrasonic pachymetry or microscopy.Mean 3,155 cells/mm2. Cell decreased with age, but sex affect cell density. Values differ significantly between right left the same horse. ventral quadrant less...

10.2460/ajvr.2001.62.479 article EN American Journal of Veterinary Research 2001-04-01

The first white Doberman pinscher (WDP) dog was registered by the American Kennel Club in 1976. novelty of coat color resulted extensive line breeding this and her offspring. WDP phenotype closely resembles human oculocutaneous albinism (OCA) clinicians noticed a seemingly high prevalence pigmented masses on these dogs. This study had three specific aims: (1) produce detailed description ocular WDPs, (2) objectively determine if an increased cutaneous melanocytic tumors present (3) genetic...

10.1371/journal.pone.0092127 article EN cc-by PLoS ONE 2014-03-19

10.1016/j.jaad.2006.05.019 article EN Journal of the American Academy of Dermatology 2006-09-15

Abstract Background Equine Multiple Congenital Ocular Anomalies (MCOA) syndrome consists of a diverse set abnormalities predominantly localized to the frontal part eye. The disease is in agreement with codominant mode inheritance our horse material. Animals presumed be heterozygous for mutant allele have cysts originating from temporal ciliary body, peripheral retina and/or iris. In contrast, animals predicted homozygous disease-causing possess wide range multiple abnormalities, including...

10.1186/1471-2156-9-88 article EN cc-by BMC Genomic Data 2008-12-01

To determine the incidence of ocular abnormalities in miniature horses.Descriptive study.Fifty-three horses.Ophthalmic examinations were performed using diffuse and focal illumination, slit-lamp biomicroscopy indirect ophthalmoscopy. Coat color, mane tail age gender recorded with results ophthalmic examination.Ocular detected most frequently consisted cysts arising from posterior iris, ciliary body, peripheral retina, curvilinear streaks retinal pigmented epithelium extending temporal...

10.1111/j.1463-5224.2010.00868.x article EN Veterinary Ophthalmology 2011-04-18

An 11-year-old Quarter Horse gelding was evaluated because of a persistent, raised band 1- to 2-mm subepithelial plaques the left cornea. Cytologic examination corneal scrapings revealed numerous eosinophils and segmented neutrophils, with few mast cells, plasma lymphocytes. Bacteriologic culture yielded sparse growth alpha-hemolytic Streptococcus Staphylococcus spp. Histologically, consisted foci fragmented degenerated collagen fibers infiltrated by lymphocytes, macrophages. Plaques were...

10.2460/javma.1994.205.09.1308 article EN Journal of the American Veterinary Medical Association 1994-11-01

Abstract Objective To investigate the changes in corneal thickness that occur during maturation of canine eye over first months life. Animals studied Dogs two different breeds with ages ranging from 14 days to 42 weeks age. Procedures The central was measured by ultrasonic pachymetry every week for month after eyelid opening (around days) and then until Segmented regression applied capture phases observed plotted against Breed, gender were also included model. Results Mean (CCT) values...

10.1046/j.1463-5224.2003.00196.x article EN Veterinary Ophthalmology 2003-03-01

Abstract We present three patients who manifested both Hodgkin disease and mycosis fungoides. Ages ranged from 39 to 66 two were male. Skin lesions 3 40 years before the diagnosis of disease. In all cases, fungoides was confirmed histologically by skin biopsy; clinical course indolent in cases. three, electron microscopy two. All responded appropriate treatment for are alive well at time.

10.1002/ajh.2830140406 article EN American Journal of Hematology 1983-06-01

Objective— To determine the outcome of implantation an intraocular silicone prosthesis ( isp ) in eyes dogs and cats with neoplasia. Design— Retrospective case series. Animals— Eight 1 cat histologically confirmed Procedure— Signalment, clinical signs before after surgery, results microscopic examination eviscerated tissues, follow-up information, necropsy findings, if available, were recorded for each animal. Results— Five had primary neoplasms. Two developed regrowth neoplasm around 6 to...

10.2460/javma.1995.207.11.1441 article EN Journal of the American Veterinary Medical Association 1995-12-01

The syndrome Multiple Congenital Ocular Anomalies (MCOA) is the collective name ascribed to heritable congenital eye defects in horses. Individuals homozygous for disease allele (MCOA phenotype) have a wide range of anomalies, while heterozygous horses (Cyst predominantly cysts that originate from temporal ciliary body, iris, and/or peripheral retina. MCOA highly prevalent Rocky Mountain Horse but not limited this breed. Affected most often Silver coat color; however, pleiotropic link...

10.1007/s00335-011-9325-7 article EN cc-by-nc Mammalian Genome 2011-04-04

Objective— To determine whether succimer ( meso -2,3-dimercaptosuccinic acid) would be effective in reducing blood lead concentration dogs with naturally acquired poisoning and treated develop clinically important adverse effects. Design— Prospective case series. Animals— 13 moderate-to-high concentrations (39 to 120 μg/dl) clinical signs of poisoning. Procedure— Dogs were (10 mg/ kg body weight, PO, q 8 h) for 10 days. Blood urine samples analyzed before, during, after treatment succimer....

10.2460/javma.1996.208.03.371 article EN Journal of the American Veterinary Medical Association 1996-02-01

To describe the clinical and histological appearance of persistent fetal intraocular vasculature in a colony ferrets. Design Prospective study.Eighty-six European ferrets (Mustela putorius). Procedure Both eyes 76 genetically related progeny 10 breeding, adult, colony-raised were studied using slit lamp biomicroscope an indirect ophthalmoscope. Ferret examined after eyelid opening at 5-6 weeks age, 12 months age. After euthanasia, globes enucleated histologically.Persistent was evident 21...

10.1046/j.1463-5224.2001.00115.x article EN Veterinary Ophthalmology 2001-03-01

To determine the electrodiagnostic and histologic response of short-term increases intraocular pressure (IOP) on transient pattern electroretinograms (PERG) flash (FERG) in eyes dogs.8 healthy mixed-breed dogs.Transient PERG FERG waveforms were recorded from dogs (while anesthetized) as IOP was increased baseline (7 to 19 mm Hg) 90 Hg. One hundred mean responses a single at each step during 3 recording sessions. Globes dog enucleated after euthanasia posttreatment day 7 evaluated by...

10.2460/ajvr.2000.61.1087 article EN American Journal of Veterinary Research 2000-09-01

Inherited ocular anomalies in chickens include several types of microphthalmia, retinal dysplasia, degeneration, cataract, buphthalmos and pop-eye, or keratoconus White Leghorns.2–5,7,8,12,15–18 In this report, a new anomaly that appeared pigmented Leghorns homozygous for mutation at the dominant white (I) locus is described with emphasis on clinical, gross, histologic findings to aid diagnosis lesions. An incompletely mutation, called Smoky Joe (SJ), allows production feather pigment, which...

10.1177/104063879700900411 article EN Journal of Veterinary Diagnostic Investigation 1997-10-01

Summary Fibrin dots were induced in eyes of dogs by injection autogenous citrated plasma into the anterior chamber. Twenty-four hours after dot formation, one 50-μl drop tissue plasminogen activator at a concentration 5 mg/ml (group 1, n = 7) was administered topically 9 times 5-minute intervals, or collagen shield that hydrated with 2, applied. The contralateral eye served as nontreated control. Serial photographs taken fibrin topical application activator. Computerized morphometric...

10.2460/ajvr.1994.55.10.1368 article EN American Journal of Veterinary Research 1994-10-01
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