Francesco Franco

ORCID: 0009-0005-8527-9980
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About
Contact & Profiles
Research Areas
  • Oral microbiology and periodontitis research
  • Periodontal Regeneration and Treatments
  • Oral Health Pathology and Treatment
  • Salivary Gland Disorders and Functions
  • Muscle Physiology and Disorders
  • Galectins and Cancer Biology
  • Metabolism, Diabetes, and Cancer
  • Autophagy in Disease and Therapy
  • Family and Disability Support Research
  • Sirtuins and Resveratrol in Medicine
  • Dental Radiography and Imaging
  • Autoimmune and Inflammatory Disorders Research
  • Adolescent and Pediatric Healthcare
  • Curcumin's Biomedical Applications
  • Monoclonal and Polyclonal Antibodies Research
  • Bone and Dental Protein Studies
  • Adipose Tissue and Metabolism
  • Glycosylation and Glycoproteins Research

University of Turin
2023-2025

The aim of this study was to test the molecular expression profile (senescence-associated secretory phenotype; SASP) in gingival crevicular fluid (GCF) prior surgery relation distribution clinical success periodontal regeneration. Forty consecutive patients presenting sites with residual probing pocket depth (PPD) ≥ 6 mm and intrabony defects 3 were treated through a minimally invasive surgical technique. Pre-operatively, GCF sampled for inflammatory biomarker analysis related SASP...

10.3390/ijms25126687 article EN International Journal of Molecular Sciences 2024-06-18

To test the effect of locally delivered doxycycline (DOX) administered 2 weeks prior to minimally invasive periodontal regeneration in terms presurgical inflammatory status and cytokine expression profile gingival crevicular fluid (GCF). Secondary aim was assess early wound healing index (EHI) at after surgery.It is hypothesized that dependent on preoperative soft tissue condition, local antibiotics may improve site-specific short time.Sites associated with intrabony defects requiring...

10.1111/jre.13174 article EN cc-by Journal of Periodontal Research 2023-08-08

Identification of biomarkers could help in assessing periodontal health status and monitoring treatment outcomes. Therefore, the aim this cross-sectional study was to identify potential innovative salivary for diagnosis periodontitis using an untargeted proteomic approach. Forty-five healthy non-smoker participants diagnosed as having periodontally conditions (H), severe (P), but reduced periodontium after active (T) were consecutively enrolled (15 per each group) study. A higher number...

10.3390/ijms241813834 article EN International Journal of Molecular Sciences 2023-09-08

Metformin (Met) is a drug commonly prescribed in type 2 diabetes mellitus. Its efficacy due to the suppression of hepatic gluconeogenesis, enhancement peripheral glucose uptake and lower absorption by intestine. Recent studies have reported Met other clinical applications, such as age-related diseases. Despite wide use Met, its mechanism action on muscle effect performance are unclear. We investigated effects combined with training physical (PP) healthy rats receiving for 8 weeks while...

10.3390/biomedicines11092334 article EN cc-by Biomedicines 2023-08-22
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