- Metal complexes synthesis and properties
- Organometallic Compounds Synthesis and Characterization
- Magnetism in coordination complexes
- Crystal structures of chemical compounds
- Organometallic Complex Synthesis and Catalysis
- Ferrocene Chemistry and Applications
- Synthesis and Characterization of Heterocyclic Compounds
- Lanthanide and Transition Metal Complexes
- Synthesis and biological activity
- Metal-Organic Frameworks: Synthesis and Applications
- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Innovative Microfluidic and Catalytic Techniques Innovation
- Phenothiazines and Benzothiazines Synthesis and Activities
- Crystallography and molecular interactions
- Inorganic and Organometallic Chemistry
- Advanced NMR Techniques and Applications
- Computational Drug Discovery Methods
- Research in Cotton Cultivation
- Quinazolinone synthesis and applications
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Medical and Biological Sciences
- EFL/ESL Teaching and Learning
- Analytical Chemistry and Chromatography
- Metal-Catalyzed Oxygenation Mechanisms
Virginia Commonwealth University
2017-2024
Tampere University
2024
University of Engineering and Technology Lahore
2008-2024
Islamia University of Bahawalpur
2014-2024
Association for Language Learning
2024
University of Sargodha
2024
Central Cotton Research Institute
2022-2024
Prince Sattam Bin Abdulaziz University
2016-2023
Yarmouk University
2023
Capital University
2022-2023
A series of potential biologically active 2-(4-hydroxy-1,1-dioxido-2H-1,2-benzothiazin-3-yl)quinazolin-4(3H)-ones was synthesized in a straight forward manner by condensation respective 4-hydroxy-1,2-benzothiazine-1,1-dioxides with anthranilamide followed simple and high throughput cyclization N-[2-(aminocarbonyl)phenyl]-4-hydroxy-1,2-benzothiazine-3-carboxamide-1,1-dioxides. All the compounds were subjected to preliminary evaluation for their biological activity against Gram positive...
Five novel Schiff bases have been prepared from o-formylphenoxyacetic acid and a series of aminothiazoles to form number potentially biologically active compounds. The structures these characterized using IR (1)H-and (13)C-NMR spectroscopy.
An efficient and environment friendly method has been described for the synthesis of various 2-alkyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxides starting from N-alkylation sodium obenzosulfimide in an ionic liquid first time. Ring cleavage ring closure resulting product were achieved a single step cost effective solvent (methanol) followed by alkyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate while boron triflouride was used as catalyst along with molecular sieves carboxamide...
The China-Pakistan Economic Corridor (CPEC), a cornerstone of China’s Belt and Road Initiative (BRI), has significantly enhanced economic connectivity, infrastructure, mobility between China Pakistan, with investments exceeding $60 billion. However, this rapid transformation raises critical questions about the intersection climate, trade mobility, public health. Increased connectivity under CPEC may amplify risk Japanese Encephalitis (JE), zoonotic, mosquito-borne disease endemic...
Ligand scrambling reactions in cyano(thione)gold(I) complexes ([>C=S-Au-CN]) to form [Au(>C=S) 2 ] + and [Au(CN) species have been investigated for a series of thiones DMSO using 13 C 15 N NMR spectroscopy. Rapid approach equilibrium occurred resulted distinct signals the [>C=S-Au-CN] complexes, both NMR. Equilibrium constants (K eq ) were determined all by integrating CN resonances recorded at 298 K. The influence various factors (initial concentration, ionic strength,...
Herein, we describe a new five-step approach to prepare 1-(3,6-dibromopyridin-2-yl)-2-(3,5-difluorophenyl)ethan-1-amine, an important intermediate in the synthesis of lenacapavir. The key step sequence is Weinreb amide-based ketone synthesis, which provides alternative entry point core structural component. Starting from inexpensive 2-(3,5-difluorophenyl)acetic acid, amide and followed nucleophilic substitution afford 47% yield. subsequent functional group manipulation delivers racemic amine...
7-Bromo-4-chloro-1H-indazol-3-amine is a heterocyclic fragment used in the synthesis of Lenacapavir, potent capsid inhibitor for treatment HIV-1 infections. In this manuscript, we describe new approach to synthesizing 7-bromo-4-chloro-1H-indazol-3-amine from inexpensive 2,6-dichlorobenzonitrile. This synthetic method utilizes two-step sequence including regioselective bromination and heterocycle formation with hydrazine give desired product an overall isolated yield 38–45%. The protocol has...