- Crystallization and Solubility Studies
- Analytical Chemistry and Chromatography
- Chemical and Physical Properties in Aqueous Solutions
- Pharmacological Effects of Natural Compounds
- Chemical Thermodynamics and Molecular Structure
- Analytical Methods in Pharmaceuticals
University of Jinan
2023-2025
The solubilities of glutathione in four binary solvent mixtures (water + acetone, water 1,4-dioxane, acetonitrile, and tetrahydrofuran) were measured using a dynamic laser monitoring method at temperatures ranging from 278.15 to 318.15 K. molar fraction solubility the increased with increasing content temperature. modified Apelblat, CNIBS/R-K, Van't Hoff–Jouyban–Acree, Apelblat–Jouyban–Acree, NRTL applied calculate these mixtures. relative average deviation root-mean-square indicated good...
The solubility of 2-[4-(dibutylamino)-2-hydroxy-benzoyl] benzoic acid (BBA) was determined in 12 pure solvents using the static equilibrium method. measurements were taken at temperatures ranging from 283.15 to 323.15 K. results indicated a positive relationship between BBA and temperature solvents, exhibited highest n-propanol lowest n-heptane. In addition, modified Apelblat, Van't Hoff, λh, Wilson models used establish correlation with experimental BBA. analysis revealed strong concordance...
The solubility of N,N'-oxalyldiglycine (OG) in 11 pure solvents, including methanol, ethanol, n-propanol, isopropyl alcohol, n-butanol, acetonitrile, ethyl acetate, tetrahydrofuran (THF), water, N,N'-dimethylformamide (DMF), and dimethyl sulfoxide (DMSO), a binary solvent system composed DMSO water was measured by dynamic laser monitoring method with the temperature ranging from 293.15 to 333.15 K. Results these experiments demonstrated that OG all solvents increases rising temperature....
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The solubility of paliperidone in 15 pure solvents (methanol, ethanol, i-propanol, n-propanol, n-butanol, n-pentanol, n-hexanol, methyl acetate, ethyl propyl butyl acetone, acetonitrile, tetrahydrofuran, and 1,4-dioxane) was determined using a dynamic laser monitoring method at 0.1 MPa temperatures ranging from 288.15 to 328.15 K. With increasing temperature, the molar fraction each solvent also increased. Acetonitrile exhibited lowest K, whereas 1,4-dioxane showed highest Various models,...