A5103077614- Bacterial biofilms and quorum sensing
- Antimicrobial Peptides and Activities
- Probiotics and Fermented Foods
- Antimicrobial agents and applications
- Nanoplatforms for cancer theranostics
- Proteoglycans and glycosaminoglycans research
- Advanced Drug Delivery Systems
- Essential Oils and Antimicrobial Activity
- Photodynamic Therapy Research Studies
- Wound Healing and Treatments
- Glycosylation and Glycoproteins Research
- Nanoparticle-Based Drug Delivery
- Protein Hydrolysis and Bioactive Peptides
- Animal Genetics and Reproduction
- Gut microbiota and health
- Traditional Chinese Medicine Analysis
- Antimicrobial Resistance in Staphylococcus
- Surgical Sutures and Adhesives
- Pneumonia and Respiratory Infections
- Phytochemicals and Antioxidant Activities
- Crystallization and Solubility Studies
- Polysaccharides and Plant Cell Walls
- Antibiotic Resistance in Bacteria
- Listeria monocytogenes in Food Safety
- Microencapsulation and Drying Processes
University of Jinan
2024-2025
China University of Petroleum, Beijing
2025
Northwest A&F University
2014-2024
Institute of Hematology & Blood Diseases Hospital
2021
Binzhou University
2018
Binzhou Medical University
2018
TIE Kinetix (Germany)
2006
Abstract The chronic infections related to biofilm and intracellular bacteria are always hard be cured because of their inherent resistance both antimicrobial agents host defenses. Herein we develop a facile approach overcome the above conundrum through phosphatidylcholine-decorated Au nanoparticles loaded with gentamicin (GPA NPs). were characterized by scanning electron microscopy (SEM), dynamic light scattering (DLS) ultraviolet−visible (UV−vis) absorption spectra which demonstrated that...
Microbial biofilms, prevalent in nature and inherently resistant to both antimicrobial agents host defenses, can cause serious problems the chemical, medical pharmaceutical industries. Herein we demonstrated that conjugation of an aminoglycoside antibiotic (streptomycin) chitosan could efficiently damage established biofilms inhibit biofilm formation. This method was suitable eradiate formed by Gram-positive organisms it appeared contents, molecular size positive charges conjugate were key...
Essential oils have been found to exert antibacterial, antifungal, spasmolytic, and antiplasmodial activity therapeutic effect in cancer treatment. In this study, the antibacterial activities of four main essential oils' components (thymol (Thy), eugenol (Eug), berberine (Ber), cinnamaldehyde (Cin)) were evaluated against two food-borne pathogens, Listeria monocytogenes Salmonella Typhimurium, either alone or combination with streptomycin. Checkerboard assay demonstrated that Thy Cin...
Probiotics were found to be effective in ameliorating the microbial dysbiosis and inflammation caused by intestinal pathogens. However, biological challenges encountered during oral delivery have greatly limited their potential health benefits. Here, a model probiotic (Lactobacillus rhamnosus) was encapsulated an intestinal-targeted hydrogel alleviate bacterial enteritis novel mode. The prepared simply self-cross-linking of thiolated hyaluronic acid. Upon exposure H2S which excreted...
Antibiotic overuse is one of the major drivers in generation antibiotic resistant "super bugs" that can potentially cause serious effects on health. In this study, we reported polycationic polysaccharide, chitosan could improve efficacy a given (gentamicin) to combat bacterial biofilms, universal lifestyle microbes world. Short- or long-term treatment with mixture and gentamicin resulted dispersal Listeria monocytogenes (L. monocytogenes) biofilms. combination, moderate molecular mass (~13...
The development of yogurt flavor is a complicated and dynamic biochemical process. In addition to traditional starter cultures, adjunct cultures could also make significant contributions the profiles yogurt. current study, two Lactobacillus plantarum strains (1-33 1-34) were isolated based on their abilities produce acetaldehyde diacetyl. co-fermentation with starters, these able maintain viability without affecting yogurt's acidification profiles. Furthermore, they positively influenced...
Summary The risk of lost circulation is a complex problem that cannot be ignored during drilling operations, and accurate assessment crucial for preventing controlling events. In this study, we establish multidimensional quantitative model based on ensemble machine learning, comprehensively considering three dimensions—formation risk, operation fluid risk. It can effectively capture quantify the interactive relationship between different factors, accuracy efficiency improved when learning...
In this study, 2-(N-pyrrolidine-alkyl) tanshinones bearing pyrrolidine groups were synthesized and the antibacterial mechanism was explored. These derivatives selectively elicited activity against Gram-positive bacteria. Moreover, their activities time-, concentration-dependent persistent. It appeared that Fenton-mediated hydroxyl radicals involved, disruption of cell membranes observed. This study indicates might be potential candidates as agents.
The emergence of biofilm-associated resistance microbes to traditional antibiotics has resulted in an urgent need for novel antimicrobial agents.
Contents MicroRNA (miRNA) is a kind of small non‐coding RNA molecules that function as important gene expression regulators by targeting messenger RNAs for post‐transcriptional endonucleolytic cleavage or translational inhibition. In this study, libraries were constructed based on adult dairy goat testicular tissues and sequenced using the Illumina high‐throughput sequencing technology. Blasted to miRNAs cow sheep in miRBase 19.0, 373 conserved identified testis 91 novel paired‐miRNAs found....