A5009902461- Lung Cancer Treatments and Mutations
- Urinary and Genital Oncology Studies
- Reproductive System and Pregnancy
- Bladder and Urothelial Cancer Treatments
- Colorectal Cancer Treatments and Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Ophthalmology and Eye Disorders
- Urological Disorders and Treatments
- Pituitary Gland Disorders and Treatments
- Genetic factors in colorectal cancer
- Cutaneous Melanoma Detection and Management
Fudan University Shanghai Cancer Center
2025
Fourth Affiliated Hospital of Guangxi Medical University
2024
Third Affiliated Hospital of Zhengzhou University
2024
191 Background: Glecirasib (JAB-21822), a highly selective, covalent and oral KRAS G12C inhibitor, has demonstrated favorable safety profile promising efficacy result as monotherapy in NSCLC. We previously reported preliminary data of glecirasib (NCT05009329) combination with cetuximab (NCT05194995) G12C-mutated advanced Colorectal Cancer (CRC); here, we present the updated results. Methods: Patients (pts) CRC harboring mutation were enrolled treated either single agent (800mg QD) or...
Abstract Study question The purpose of this study was to investigate the effect ERA on pregnancy outcomes in patients with RIF. Summary answer results showed no significant difference who received compared those did not. What is known already One potential cause implantation failure abnormal endometrial receptivity, and how objectively evaluate receptivity has been a matter great concern. Endometrial analysis (ERA), microarray-based test that assesses gene expression, may be valuable...
The nested subtype of urothelial carcinoma (NS-UC), a rare and aggressive bladder cancer, mimics benign lesions but behaves like high-grade carcinomas. author reported case NS-UC, initially presenting with inguinal lymph node metastasis. tumor cells NS-UC exhibit minimal cellular atypia, forming small nests, while the metastatic show greater atypia diverse structures. Immunohistochemistry is helpful in determining origin carcinoma. often presents morphologically similar to lesions, which...
Objective: This study was conducted to analyze the clinical characteristics and pituitary function of patients with primary empty sella (PES). Methods: The data from 123 hospitalized adult PES January 2010 May 2016 were retrospectively studied. Results: (1) average age (male 43, female 80) (59.2±13.6) years (ranging 24-92 years), among whom 61% in group between 50-69 years. (2) symptoms included fatigue (56.1%), headache (34.1%), nausea vomiting (17.9%), gonadal dysfunction (17.1%), visual...