A5023765074- Connexins and lens biology
- Hair Growth and Disorders
- RNA regulation and disease
- Dietary Effects on Health
- Contact Dermatitis and Allergies
- Mast cells and histamine
- Paraoxonase enzyme and polymorphisms
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Health Systems, Economic Evaluations, Quality of Life
- Phagocytosis and Immune Regulation
- Genetic Mapping and Diversity in Plants and Animals
- RNA Research and Splicing
- Childhood Cancer Survivors' Quality of Life
- Spine and Intervertebral Disc Pathology
- Traumatic Brain Injury and Neurovascular Disturbances
- Extracellular vesicles in disease
- Diet and metabolism studies
- Gut microbiota and health
- RNA Interference and Gene Delivery
- Cardiovascular Disease and Adiposity
- Skin and Cellular Biology Research
- Cell Adhesion Molecules Research
- Parkinson's Disease Mechanisms and Treatments
- Spinal Fractures and Fixation Techniques
- melanin and skin pigmentation
Capital Medical University
2024
People's Hospital of Xinjiang Uygur Autonomous Region
2024
Wenzhou Medical University
2024
Sichuan University
2024
Zhejiang Chinese Medical University
2024
Beijing Chao-Yang Hospital
2024
Anhui University
2004-2005
Anhui Medical University
2004-2005
Institute of Dermatology
2004
Dysbiosis of the gut microbiota has been implicated in hypertension, and drug-host-microbiome interactions have drawn considerable attention. However, influence angiotensin receptor blocker (ARB)-shaped on host is not fully understood. In this work, we assessed alterations blood pressure (BP), vasculatures, intestines following ARB-modified microbiome treatment evaluated changes intestinal transcriptome serum metabolome hypertensive rats. Hypertensive patients with well-controlled BP under...
Skin, being the body's largest organ, is susceptible to injuries. Despite adoption of common treatments such as debridement, wound dressing, and infection control measures for skin injuries, outcomes remain unsatisfactory, especially in diabetic patients or elderly patients. The use adipose stem cell-derived apoptotic extracellular vesicles (apoEVs-ASCs) has been shown great therapeutic potential repair. effect donor age on biological properties functions apoEVs-ASCs not reported.
Background Punctate palmoplantar keratoderma (PPK) is a rare autosomal dominant cutaneous disorder characterized by numerous hyperkeratotic papules distributed on the palms and soles. Two loci for punctate PPK were recently found to be located 8q24.13–8q24.21 15q22–15q24. However, no genes this disease have been identified date. Objectives To refine previously mapped regions identify gene locus in four‐generation Chinese family with PPK. Methods Genetic linkage analysis was carried out using...
Dyschromatosis symmetrica hereditaria (DSH) is a pigmentary genodermatosis of autosomal dominant inheritance characterized by mixture hyperpigmented and hypopigmented macules distributed on the dorsal aspects hands feet. It caused mutations RNA-specific adenosine deaminase gene. We report identification Chinese family with three-generation pedigree DSH, in whom novel tyrosine substitution mutation DSRAD was demonstrated: heterozygous nucleotide A→G transition at position 2879 exon 10 gene detected.
Abstract Mutations in the Paraoxonase 1 ( Pon1 ) gene underlie aging, cardiovascular disease, and impairments of nervous gastrointestinal systems are linked to intestinal microbiome. The potential role modulating microbiota serum metabolites is poorly understood. present study demonstrated that mice with genomic excision by a multiplexed guide RNA CRISPR/Cas9 approach exhibited disrupted gut microbiota, such as significantly depressed alpha‐diversity distinctly separated beta diversity,...
Journal Article Refinement of a locus for Marie Unna hereditary hypotrichosis to 1·1‐cM interval at 8p21.3 Get access P.P. He, He Institute Dermatology and Department No. 1 Hospital, Anhui Medical University, Key Laboratory Genome Research Anhui, 69 Meishan Road, Hefei, 230032 ChinaChinese National Human Center Shanghai, 250 Bi Bo 201203 China Search other works by this author on: Oxford Academic Google Scholar X.J. Zhang, Zhang Xue‐Jun Zhang. E‐mail: ayzxj@mail.hf.ah.cn Q. Yang, Yang M. Li,...
It has been shown that many antihistamines may have anti-inflammatory activity in addition to being H1 antagonists. Mizolastine (MIZ), a novel antihistamine, might also anti-angiogenesis properties. In this study, we investigated the influence of MIZ on proangiogenesis factors, vascular endothelial cell growth factor (VEGF), tumour necrosis (TNF)-alpha and keratinocyte-derived chemokine (KC) murine mast cells by using ELISA RT-PCR, as compared with dexamethasone (DEX) loratadine (LOR). Our...
Journal Article Marie Unna hereditary hypotrichosis: report of a Chinese family and evidence for genetic heterogeneity Get access K. L. Yan, Yan Institute Dermatology & Department at No. 1 Hospital, Anhui Medical University, Hefei, ChinaKey Laboratory Genome Research Anhui, China Search other works by this author on: Oxford Academic Google Scholar P. He, He S. Yang, Yang M. Li, Li Q. Y. Ren, Ren Cui, Cui Gao, Gao F. Xiao, Xiao W. Huang, Huang National Human Center Shanghai, ... Show more X....
To investigate the protective effect of carvedilol against atherosclerosis by inhibiting NLRP3 inflammasome.