- Antimicrobial Resistance in Staphylococcus
- Clostridium difficile and Clostridium perfringens research
- Streptococcal Infections and Treatments
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Attention Deficit Hyperactivity Disorder
- Dementia and Cognitive Impairment Research
- Health and Well-being Studies
- Decision-Making and Behavioral Economics
- Smoking Behavior and Cessation
- Neurological Disease Mechanisms and Treatments
- Intelligent Tutoring Systems and Adaptive Learning
- Advanced Neuroimaging Techniques and Applications
- Neural and Behavioral Psychology Studies
- Balance, Gait, and Falls Prevention
- Nerve injury and regeneration
- Health Policy Implementation Science
- Antibiotic Use and Resistance
- Criminal Justice and Corrections Analysis
- Management and Marketing Education
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Forensic Toxicology and Drug Analysis
- Memory Processes and Influences
- Cerebral Palsy and Movement Disorders
- Infective Endocarditis Diagnosis and Management
- Behavioral Health and Interventions
University of Liège
2020-2024
Imagerie et Cerveau
2020
Columbia University Irving Medical Center
2019
Royal College of Physicians
2015
Columbia University
2010-2014
Allen Institute for Brain Science
2012
University Physicians
2012
University Radiology
2012
Medical University of South Carolina
2012
BACKGROUND New-onset Alzheimer disease (AD) is often attributed to degenerative changes in the hippocampus. However, contribution of regionally distributed small vessel cerebrovascular disease, visualized as white matter hyperintensities (WMHs) on magnetic resonance imaging, remains unclear. OBJECTIVE To determine whether regional WMHs and hippocampal volume predict incident AD an epidemiological study. DESIGN A longitudinal community-based study older adults from northern Manhattan, New...
Abstract In this article, we discuss some of the challenges encountered while conducting research in two maximum security prisons and approaches found helpful to facilitate process through development collaborative relationships, establishment prison contacts, implementation rigorous methods. As a result our experiences, have been successful at maintaining high rate inmate participation (>80%) well‐functioning multidisciplinary team. The described may be useful other investigators...
Throat carriage (42.7%) of Staphylococcus aureus exceeded nasal (35.0%) in 2 New York prisons. Methicillin resistance, primarily due to USA300, was high at both sites; 25% dually colonized inmates had different strains. Strategies reduce S. transmission will need consider the frequency throat colonization.
Cognition and mobility are interrelated. However, this association can be impacted by the specific facets of cognition that measured, further different task conditions, e.g., single- versus dual-task walking, under which these associations evaluated. Systematically studying multiple cognitive-mobility both conditions is critical because change with age pose significant risks associated falls, morbidity, disability.Using a cross-sectional, prospective study design, data from 124 healthy...
Objective: We compared the relationships among sex, clustering strategy, and recall across different task demands using 16-word California Verbal Learning Test-Second Edition (CVLT-II) 9-word Philadelphia (repeatable) Test (PrVLT). Background: Women generally score higher than men on verbal memory tasks, possibly because women tend to use semantic clustering. This sex difference has been established via word-list learning tests such as CVLT-II. Methods: In a retrospective between-group...
SUMMARY To assess the prevalence and risk factors for colonization with Staphylococcus aureus in inmates entering two maximum-security prisons New York State, USA, ( N = 830) were interviewed anterior nares oropharyngeal samples collected. Isolates characterized using spa typing. Overall, 50·5% of women 58·3% men colonized S. 10·6% 5·9% MRSA at either or both body sites. Of MSSA isolates, major subtypes type 008 002. varied by gender only found included younger age, fair/poor self-reported...
Background and objectives Genetic variability in the dopaminergic system could contribute to age-related impairments executive control. In this study, we examined whether genetic polymorphism for catechol-O-methyltransferase (COMT Val 158 Met) is related performance on updating, shifting inhibition tasks. Methods We administered a battery of tasks assessing functions 45 older 55 younger healthy participants, created composite z-scores associated each function. Six groups were based alleles...
Over the past decade, large outbreaks of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections have occurred in correctional facilities across country. Although many been managed with aggressive interventions, response to standard infection control procedures has variable, highlighting our incomplete understanding staphylococcal transmission this setting. Environmental contamination recently emerged as a possible target for novel prevention and strategies....
Background. Large outbreaks of Staphylococcus aureus (SA) infections have occurred in correctional facilities across the country. We aimed to define epidemiological and microbiological determinants SA infection prisons facilitate development prevention strategies for this underserved population. Methods. conducted a case-control study at 2 New York State maximum security prisons. SA-infected inmates were matched with 3 uninfected controls. Subjects had cultures taken from sites colonization...
Background and objective. Genetic variability in the dopaminergic system could contribute to age-related impairments executive control. In this study, we examined whether genetic polymorphism for catechol-O-methyltransferase (COMT Val158Met) is related performance on updating, shifting inhibition tasks. Method. We administered a battery of tasks assessing functions 45 older 55 younger healthy participants, created composite z-scores associated each function. Six groups were based alleles...
Small vessel cerebrovascular disease, visualized as white matter hyperintensities (WMH) on MRI, has been linked to age-associated cognitive dysfunction, but whether it is related Alzheimer's disease (AD) unclear. This study examined the regional distribution of WMH among older adults at high risk for developing AD drawn from a cohort community-dwelling adults. Because hippocampal atrophy, putative marker neurodegeneration, typically increased patients with AD, we also compared ability volume...