A5037633954- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Cytokine Signaling Pathways and Interactions
- Respiratory and Cough-Related Research
- Vasculitis and related conditions
- Lung Cancer Diagnosis and Treatment
- Adsorption and biosorption for pollutant removal
- Estrogen and related hormone effects
- Eosinophilic Disorders and Syndromes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- SARS-CoV-2 and COVID-19 Research
- Arsenic contamination and mitigation
- Fluoride Effects and Removal
- IL-33, ST2, and ILC Pathways
- Urticaria and Related Conditions
Huazhong University of Science and Technology
2021-2025
Tongji Hospital
2021-2025
National Clinical Research Center for Digestive Diseases
2021-2023
National Health and Family Planning Commission
2021-2023
Abstract To describe the long-term health outcomes of patients with COVID-19 and investigate potential risk factors. Clinical data during hospitalization at a mean (SD) day 249 (15) days after discharge from 40 survivors confirmed (including 25 severe cases) were collected analyzed retrospectively. At follow-up, cases had higher incidences persistent symptoms, DLCO impairment, abnormal CT score as compared mild cases. follow-up was positively correlated age, LDH level, cumulative oxygen...
Neutrophilic asthmatics (NA) have less response to inhaled corticosteroids. We aimed find out the predictor of treatment in NA.Asthmatics (n = 115) and healthy controls 28) underwent clinical assessment during 6-month follow-up with standardized therapy. Asthmatics were categorized by sputum differential cell count. The mRNA expressions measured RT-qPCR for cytokines (IFN-γ, IL-1β, IL-27, FOXP3, IL-17A, IL-5). protein IL-1β supernatant was detected ELISA. Reticular basement membranes (RBM)...
Although estrogen receptors (ERs) signal pathways are involved in the pathogenesis and development of asthma, their expressions effects remain controversial. This study aimed to investigate ERα ERβ as well mechanisms airway remodeling mucus production asthma.The epithelial cells bronchial biopsies induced sputum were examined by immunohistochemistry. The associations ERs with inflammation evaluated asthmatic patients. In vitro, regulations human cell lines using western blot analysis....
Background Asthma patients potentially have impaired adaptive immunity to virus infection. The levels of SARS-CoV-2-specific between COVID-19 survivors with and without asthma are presently unclear. Methods (patients n=11, allergies n=8, only n=17) non-COVID-19 individuals (asthmatic n=10 healthy controls n=9) were included. followed up at about 8 months 16 after discharge. clinical characteristics, lymphocyte subsets, memory T cells, humoral including SARS-CoV-2 specific antibodies,...