P Casanova
- Diet and metabolism studies
- Viral gastroenteritis research and epidemiology
- Bacterial biofilms and quorum sensing
- Antibiotics Pharmacokinetics and Efficacy
- Liver Disease Diagnosis and Treatment
- Blood disorders and treatments
- Gut microbiota and health
- Pleural and Pulmonary Diseases
- Metabolomics and Mass Spectrometry Studies
- Escherichia coli research studies
- Antibiotic Resistance in Bacteria
- Legionella and Acanthamoeba research
- Medical Imaging and Pathology Studies
- Selenium in Biological Systems
- Trace Elements in Health
- Congenital Diaphragmatic Hernia Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Stress and Burnout Research
- Hematological disorders and diagnostics
- Chronic Disease Management Strategies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diagnosis and treatment of tuberculosis
- Pharmacology and Obesity Treatment
- Diabetes Treatment and Management
- Infectious Diseases and Tuberculosis
INCLIVA Health Research Institute
2023-2025
Universitat de València
2022-2025
Joslin Diabetes Center
2025
Harvard University
2025
Hospital Universitario Puerta del Mar
2002
George Washington University
2000
OBJECTIVE: The Diabetes Prevention Program (DPP) is a 27-center randomized clinical trial designed to evaluate the safety and efficacy of interventions that may delay or prevent development diabetes in people at increased risk for type 2 diabetes. RESEARCH DESIGN AND METHODS: Eligibility requirements were age > = 25 years, BMI 24 kg/m2 (> 22 Asian-Americans), impaired glucose tolerance plus fasting plasma 5.3-6.9 mmol/l (or < 6.9 mmol American Indians). Randomization...
The objective of this study was to analyse whether there is an association between reduced susceptibility biocides in Acinetobacter baumannii and (i) antimicrobial resistance (co-resistance), (ii) prevalent (epidemic) clones, (iii) changes the fitness or (iv) expression genes related efflux pumps porins. Susceptibility antimicrobials determined 49 clonally unrelated isolates A. baumannii. Biological cost, terms mean generation time, by spectrophotometry. Quantitative real-time RT–PCR used...
BackgroundCarbapenem-resistant Acinetobacter baumannii (CRAb) is a major source of nosocomial infections in Spain associated with the production OXA-58-like or OXA-24/40-like β-lactamase enzymes. We analysed plasmids carrying blaOXA-24/40-like gene CRAb isolates obtained decade apart.
Metabolic-dysfunction-associated steatotic liver disease (MASLD) affects around 30% of the global population. The sexual dimorphism and gut microbiota play an important role in early development MASLD. main objective this research was to investigate metabolic changes during subclinical MASLD progression, for identifying sequence events evaluating impact on initial stages development. Male female Wistar rats 18 weeks old were randomly divided into different groups fed a chow diet or 45%...
Non-alcoholic fatty liver disease (NAFLD) is a condition in which excess fat builds up the liver. To date, there lack of knowledge about subtype lipid structures affected early stages NAFLD. The aim this study was to analyze serum and moieties, specifically unsaturations carbonyls, by nuclear magnetic resonance (NMR) subclinical Wistar rat model NAFLD for detecting alterations potential sex dimorphisms. Twelve weeks high-fat diet (HFD) induced accumulation similar extent male female rats. In...
Journal Article Meningeal penetration of apalcillin in man Get access D. Raoult, Raoult *Clinique des Maladies Infectieuses, Hôpztal F. Houphouet Boigny13015, Marseille, France Search for other works by this author on: Oxford Academic PubMed Google Scholar H. Gallias, Gallias P. Casanova, Casanova A. Bedjaoui, Bedjaoui †Laboratoire Fran Çaise de ThérapeutiqueB.P.61, 33033, Bordeaux, R. Akbaraly, Akbaraly J. Auzerie Antimicrobial Chemotherapy, Volume 15, Issue 1, January 1985, Pages 123–125,...
Metabolomics, which is the latest state-of-the-art omics platform, provides identification and quantitation of all metabolites in a sample, known as cellular end products metabolic reactions. These reactions could be key factor development surrounding complications involved cardiometabolic disease (CMD). This includes cluster risk factors such obesity, hypertension, fatty liver disease, type 2 diabetes cardiovascular disease. Therefore, study metabolism at first stages CMD potential early...