A5012212891- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Pulmonary Hypertension Research and Treatments
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Pericarditis and Cardiac Tamponade
- Infective Endocarditis Diagnosis and Management
- Coronary Interventions and Diagnostics
- Cardiovascular Disease and Adiposity
- Cardiovascular Effects of Exercise
- Peripheral Artery Disease Management
- Diabetes Treatment and Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Myasthenia Gravis and Thymoma
- Aortic Disease and Treatment Approaches
- Chemotherapy-induced cardiotoxicity and mitigation
- Kawasaki Disease and Coronary Complications
- Emergency and Acute Care Studies
- IgG4-Related and Inflammatory Diseases
National Heart Centre Singapore
2015-2024
Sengkang General Hospital
2024
University of Liège
2017-2022
National University of Singapore
2019
Centre Hospitalier Universitaire de Liège
2017
To obtain the normal ranges for 2D echocardiographic (2DE) measurements of left ventricular (LV) strain from a large group healthy volunteers accounting age and gender. A total 549 (mean age: 45.6 ± 13.3 years) subjects were enrolled at 22 collaborating institutions Normal Reference Ranges Echocardiography (NORRE) study. 2DE data sets have been analysed with vendor-independent software package allowing homogeneous irrespective equipment used to acquire sets. The lowest expected values LV...
To obtain the normal ranges for 2D echocardiographic (2DE) indices of myocardial work (MW) from a large group healthy volunteers over wide range ages and gender. A total 226 (85 men, mean age: 45 ± 13 years) subjects were enrolled at 22 collaborating institutions Normal Reference Ranges Echocardiography (NORRE) study. Global index (GWI), global constructive (GCW), waste (GWW), efficiency (GWE) estimated left ventricle (LV) pressure–strain loops. Peak LV systolic pressure was non-invasively...
To obtain the normal ranges for echocardiographic measurements of left atrial (LA) function from a large group healthy volunteers accounting age and gender. A total 371 (median 45 years) subjects were enrolled at 22 collaborating institutions in Normal Reference Ranges Echocardiography (NORRE) study European Association Cardiovascular Imaging (EACVI). Left data sets analysed with vendor-independent software (VIS) package allowing homogeneous irrespective equipment used to acquire sets. The...
The assessment of post-myocardial infarction (MI) left ventricular (LV) remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined echocardiography. Our aim was to provide CMR for assessing LV following acute MI. Firstly, 40 reperfused ST-segment elevation myocardial (STEMI) patients with paired (4 ± 2 days) and follow-up (5 months) scans were analyzed independent reviewers the minimal detectable changes (MDCs) percentage change in end-diastolic volume (%ΔLVEDV),...
To obtain the normal range for 2D echocardiographic (2DE) measurements of left ventricular (LV) layer-specific strain from a large group healthy volunteers both genders over wide ages.A total 287 (109 men, mean age: 46 ± 14 years) subjects were enrolled at 22 collaborating institutions EACVI Normal Reference Ranges Echocardiography (NORRE) study. Layer-specific was analysed apical two-, three-, and four-chamber views using 2DE software. The lowest values calculated as ±1.96 standard...
This study aimed to evaluate the modification of non-invasive myocardial work (MW) indices related aortic stenosis (AS) stages cardiac damage and their prognostic value. The echocardiographic outcome data 170 patients, with asymptomatic moderate-to-severe AS left ventricular ejection fraction (LVEF) ≥ 50%, 50 age- sex-comparable healthy controls were analysed. Primary endpoints occurrence all-cause cardiovascular death. Increased values global index (GWI), constructive (GCW), wasted (GWW)...
Phaeochromocytoma multisystem crisis (PMC) is characterized by labile blood pressures (extremes of hypo- and/or hypertension) and multiorgan failure as a result catecholamine excess. Initial stabilization requires pharmacological mechanical circulatory support, followed the institution antihypertensives to correct underlying pathophysiology.
Introduction: Numerous heart failure risk scores have been developed but there is none for Asians. We aimed to develop a calculator, the Singapore Heart Failure Risk Score, predict 1- and 2-year survival in Southeast Asian patients hospitalised failure. Materials Methods: Consecutive admitted were identified from Cardiac Databank registry. The follow-up was 2 4 years mortality obtained national registries. Results: derivation (2008-2009) validation cohorts (2008-2009, 2013) included 1392,...
Graphical AbstractValvular heart disease sex differences in presentation, management, and outcome. AR, aortic regurgitation; BAV, bicuspid valve; EORP, EURObservational Research Programme; MR, mitral MS, stenosis; NYHA, New York Heart Association; TR, tricuspid regurgitationOpen new tabDownload slide
RESUlTSOf the 365 respondents, 40.9% were male, 70.3% Chinese, 18.8% Malay and 10.9% Indian.The mean age was 47.5 years.Although 81.9% of respondents had medical check-ups involving blood tests, only 11.0% knew their actual cholesterol levels.A third saw herbal medicine as healthier safer than Western medication.More 80% believed that diet exercise equally effective at lowering medication.About half associated long-term use statins with damage to liver kidney, while a chronic statin...