A5025103823- Animal Virus Infections Studies
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Microbial infections and disease research
- Gut microbiota and health
- Emotional Intelligence and Performance
- International Student and Expatriate Challenges
- Mycobacterium research and diagnosis
- Educational Methods and Teacher Development
- Viral Infections and Vectors
- Ectopic Pregnancy Diagnosis and Management
- Clostridium difficile and Clostridium perfringens research
- Animal Disease Management and Epidemiology
- SARS-CoV-2 and COVID-19 Research
Centre de Recerca en Sanitat Animal
2008-2024
Universitat Autònoma de Barcelona
2008-2024
Institute of Agrifood Research and Technology
2023
PCV-2 is considered one of the most economically important viral agents in swine worldwide. Recently, PCV-3 has been found pigs affected by different disorders and healthy animals. The objective this epidemiological work was to describe frequency detection pig farms 9 European countries. Moreover, a second aim assess frequent genotypes studied farms. Sera from 5 10 per farm were collected 2 11 country. A total 624 sera fattening (10–25 week old) 64 Spain (n = 11), Belgium 10), France 8),...
Abstract Porcine circovirus 2 (PCV2) is a single stranded DNA virus with one of the highest mutation rates among viruses. This ability allows it to generate cloud mutants constantly providing new opportunities adapt and evade immune system. pig pathogen associated many diseases, globally called porcine diseases (PCVD) has been threat industry since its discovery in early 90’s. Although 11 ORFs have predicted from genome, only two main proteins deeply characterized, i.e. Rep Cap. The...
Vaccination against porcine circovirus 2 (PCV-2) is a common practice all over the world. Vaccines can prevent PCV-2-systemic disease (PCV-2-SD) outbreaks but not PCV-2 infection, which be detectable in percentage of vaccinated animals. Occasionally, PCV-2-SD diagnosed farms. The objective this study was to genotype strains detected animals with PCV-2-SD. Additionally, evolution frequency detection at Spanish, European, and world levels assessed. Fifty cases as between 2009 2020 were...
Porcine circovirus 3 (PCV-3) is the third member of family Circoviridae, genus Circovirus, able to infect swine. A high prevalence viral DNA has been recorded in wild boars. Recently, PCV-3 was identified Italian ruminants. Based on these previous results, this study assessed frequency detection free-ranging ruminants and Lagomorpha species Spain. In addition, genetic characterization PCR-positive samples performed. total 801 serum samples, including red deer (Cervus elaphus, [CE]; n = 108),...
Porcine circovirus 3 (PCV-3) has been detected in cases of reproductive failure but the pathogenesis such infection is poorly understood. So far, experimental PCV-3 inoculations have performed only piglets. Therefore, through inoculation pregnant gilts at two different time points (second and last third gestation), this study aimed to evaluate outcome dams their offspring until weaning age. Two weeks postinoculation, all became viremic lasted end study. Farrowing occurred naturally, without...
Abstract The nasal microbiota plays an important role in animal health and the use of antibiotics is a major factor that influences its composition. Here, we studied consequences intensive antibiotic treatment, applied to sows and/or their offspring, on piglets’ microbiota. Four pregnant were treated with crystalline ceftiofur tulathromycin (CT ) while two other received only (C ). Sow treatments performed at D-4 (four days pre-farrowing), D3, D10 D17 for D-3, D4 D11 tulathromycin. Half...
Abstract Background The objective of the present study was to explore benefits Porcine circovirus 2 (PCV-2) blanket vaccination in a sow herd on productive parameters, PCV-2 infection and immune status sows their progeny. For this purpose, 288 were distributed among four balanced experimental groups. One group remained as negative control other three received 1 mL Ingelvac Circoflex® intramuscularly at different cycle moments: before mating, mid gestation (42–49 days post-insemination) or...
Porcine circovirus 3 (PCV-3) is a recently discovered pathogen of swine that has been associated with several conditions. However, many questions remain unanswered regarding its infection, especially in terms pathogenesis and disease impact. The aim the present study was to retrospectively investigate presence PCV-3 genome by real time quantitative PCR (qPCR) situ hybridization (ISH) on selected formalin-fixed paraffin-embedded tissues pigs affected different clinical conditions histological...
Abstract Background Mycoplasma hyopneumoniae (Mhyo) and Porcine circovirus 2 (PCV-2) are two of the most significant infectious agents causing economic losses in weaning to slaughter period. Due their similar vaccination age, objective this study was assess efficacy already existing Mhyo (Hyogen®) PCV-2 (Circovac®) vaccines when administered separately or combined (RTM) by means experimental challenges. Results Seven groups animals were included study, being three them challenged with PCV-2,...
Four studies under preclinical and clinical conditions were performed to evaluate the efficacy of a new trivalent vaccine against Porcine circovirus 2 (PCV-2) infection. The product contained inactivated PCV-1/PCV-2a (cPCV-2a) PCV-1/PCV-2b (cPCV-2b) chimeras, plus
Porcine circovirus 3 (PCV-3) has been associated with several pig diseases. Despite the pathogenicity of this virus not completely clarified, reproductive disorders are consistently its infection. The aim present work was to analyze presence PCV-3 DNA in tissues from fetuses different gestational timepoints. were obtained either farms no problems (NRP, n = 249; all them last third gestation) or a slaughterhouse (S, 51; 49 second-third gestation and 2 one). Tissues collected included brain,...
Porcine dermatitis and nephropathy syndrome (PDNS) is a severe condition that affects mainly growing pigs considered to be caused by type III hypersensitivity reaction. Although porcine circovirus 2 (PCV-2) the antigen linked this condition, 3 (PCV-3) has also been proposed causally associated with PDNS. Moreover, initial description of 4 (PCV-4) related novel agent clinicopathological entity. Therefore, retrospective study included large number PDNS cases (n = 102) fulfilling specific...
Abstract Background Porcine circovirus 3 (PCV3) is a recently discovered swine pathogen associated with reproductive disease. To date, clinical problems linked to PCV3 have been described in intensive rearing pig farms. The present case describes an Iberian semi-outdoors sow farm affected by Case presentation was composed of 420 self-replaced sows, working 3-week batches (60 sows per batch). free from porcine and respiratory syndrome virus (PRRSV) had previously 2 (PCV2) disease, which...
Up to now, information on the levels of maternally-derived antibodies (MDA) against PCV-2 in suckling piglets born sows vaccinated with different strategies is scarce literature. In present observational study, PCV-2-specific MDA titres from 109 farms (thirty 3-day-old and thirty 21-day-old per farm) across four European countries (France n = 30, Germany 27, Italy 22 Spain 30) using sow vaccination (during gestation, as a gilt, piglet or never) were assessed.In all countries, mean log higher...
Abstract Nasal microbiota plays an important role in animal health and the use of antibiotics is one major factors that influence its composition. Here, we study consequences on piglets’ nasal when intensive antibiotic treatment was applied to sows and/or their piglets. Four pregnant received a ceftiofur tulathromycin (CT ) while two other only crystalline (C ). Sow treatments were performed at D-4, D3 D10 for D-3, D4 D11 tulathromycin. Half piglets born CT treated birth with ceftiofur....