A5077374842- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Animal Disease Management and Epidemiology
- Cardiac, Anesthesia and Surgical Outcomes
- Microbial infections and disease research
- Tuberculosis Research and Epidemiology
- Health and Medical Education
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Immunology Research
- Mycobacterium research and diagnosis
- Child and Adolescent Health
- Leptospirosis research and findings
- Appendicitis Diagnosis and Management
- COVID-19 and healthcare impacts
- Immune responses and vaccinations
- Colorectal Cancer Surgical Treatments
- Ethics and bioethics in healthcare
- Animal Nutrition and Physiology
- Veterinary medicine and infectious diseases
- Vector-Borne Animal Diseases
- COVID-19 Clinical Research Studies
- Anesthesia and Pain Management
- Pediatric Pain Management Techniques
- Abdominal Surgery and Complications
Universitat Autònoma de Barcelona
2013-2024
National University of the Littoral
2023
Centre de Recerca en Sanitat Animal
2012-2022
Universidad de Ciencias Médicas de Cienfuegos
2008-2021
ORCID
2020-2021
Hospital Clínico de la Universidad de Chile
2020
Hospital Universitario de Gran Canaria Doctor Negrín
2020
Deleted Institution
2006-2019
Texas Tech University
2013-2015
The University of Texas at El Paso
2013-2014
The lack of available vaccines against African swine fever virus (ASFV) means that the evaluation new immunization strategies is required. Here we show fusion extracellular domain ASFV Hemagglutinin (sHA) to p54 and p30, two immunodominant structural viral antigens, exponentially improved both humoral cellular responses induced in pigs after DNA immunization. However, with resulting plasmid (pCMV-sHAPQ) did not confer protection lethal challenge virulent E75 ASFV-strain. Due fact CD8(+)...
African swine fever is one of the most devastating pig diseases, against which there no vaccine available. Recent work from our laboratory has demonstrated protective potential DNA vaccines encoding three viral antigens (p54, p30, and hemagglutinin extracellular domain) fused to ubiquitin. Partial protection was afforded in absence detectable antibodies prior virus challenge, survival correlated with presence a large number hemagglutinin-specific CD8(+) T cells blood. Aiming demonstrate...
Abstract The present study characterized the homologous and heterologous immune response in type-I porcine reproductive respiratory syndrome virus (PRRSV) infection. Two experiments were conducted: experiment 1, eight pigs inoculated with PRRSV strain 3262 84 days post-inoculation (dpi) they challenged either or 3267 followed for next 14 (98 dpi). In 2, at dpi as above. Clinical course, viremia, humoral (neutralizing non-neutralizing antibodies, NA) virus-specific IFN-γ responses (ELISPOT)...
Caprine tuberculosis (TB) has increased in recent years, highlighting the need to address problem infection poses goats. Moreover, goats may represent a cheaper alternative for testing of prototype vaccines large ruminants and humans. With this aim, Mycobacterium caprae model been developed Eleven 6-month-old were infected by endobronchial route with 1.5 × 10(3) CFU, two other kept as noninfected controls. The animals monitored clinical immunological parameters throughout experiment. After...
ABSTRACT This is the first efficacy study using experimental goat model, a natural host of tuberculosis (TB), to evaluate heterologous Mycobacterium bovis bacillus Calmette-Guérin (BCG) prime followed by boosting with replication-deficient adenovirus expressing antigen Ag85A (AdAg85A). Three groups 11 kids each were used: BCG vaccinated, vaccinated and AdAg85A boosted, nonvaccinated. Twenty-two ∼5 × 10 5 CFU (week 0), them boosted at week 8 9 PFU AdAg85A. At 14, all goats challenged...
This study aimed to determine the porcine circovirus type 2 (PCV2) serological and virological dynamics in piglets vaccinated at different ages a PCV2 subclinical infection (PCV2-SI) scenario. Six hundred forty-four week-old healthy were selected distributed into four treatment groups: vaccination 3, 6 or 10 weeks of age (3W-VAC, 6W-VAC 10W-VAC groups, respectively) unvaccinated pigs (NON-VAC group). Blood (n = 112 pigs) oral fluid (OF) 40 pens) samples taken throughout assess load, humoral...
Most countries carrying out campaigns of bovine tuberculosis (TB) eradication impose a ban on the use mycobacterial vaccines in cattle. However, vaccination against paratuberculosis (PTB) goats is often allowed even when its effect TB diagnosis has not been fully evaluated. To address this issue, goat kids previously vaccinated PTB were experimentally infected with TB. Evaluation interferon-γ (IFN-γ) secretion induced by avian and tuberculins (PPD) showed predominant PPD-biased response...
Understanding the spread of Toxoplasma gondii (T. gondii) in wild birds, particularly those with opportunistic feeding behavior, is interest for elucidating epidemiological involvement these birds maintenance and dissemination parasite. Overall, from 2009 to 2011, we collected sera 525 seagull chicks (Yellow-legged gull (Larus michahellis) Audouin's (L. audouinii)) 6 breeding colonies Spain tested them using modified agglutination test (MAT) presence antibodies against T. gondii. Chick age...
An experiment was conducted to determine whether spray-dried porcine plasma containing 2.47 x 10(5) dna copies of circovirus type 2 (pcv-2) could infect weanling pigs when fed them. Five specific pathogen-free (spf) were ad libitum for 45 days a control diet and six test 8 kg sdpp per 100 feed. The two groups housed in separate biosecurity level-3 rooms. None the either group developed any clinical signs or became pcv-2 viraemic seroconverted.