A5091297197- Atmospheric chemistry and aerosols
- Atmospheric Ozone and Climate
- Chronic Obstructive Pulmonary Disease (COPD) Research
- High Altitude and Hypoxia
- Atmospheric and Environmental Gas Dynamics
- Paraquat toxicity studies and treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Atmospheric aerosols and clouds
- Occupational exposure and asthma
- Occupational and environmental lung diseases
- Medicinal Plants and Bioactive Compounds
- Acute Kidney Injury Research
- Toxic Organic Pollutants Impact
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Effects and risks of endocrine disrupting chemicals
- Per- and polyfluoroalkyl substances research
Lanzhou University
2012-2023
Nano nickel oxide (NiO), widely used in industry, has recently been discovered to have pulmonary toxicity. However, no subchronic exposure studies about nano NiO-induced fibrosis reported. The objective of this study was investigate induced by NiO and its potential mechanism rats. Male Wistar rats ( n = 40, 200-240 g) were randomized into control group, groups (0.015, 0.06, 0.24 mg/kg), micro group (0.024 mg/kg). All killed collect lung tissue after intratracheal instillation particles twice...
Paraquat (PQ) is one of the most widely used herbicides in world and can cause pulmonary fibrosis cases with intoxication. Losartan, an angiotensin II type 1 receptor antagonist, has beneficial effects on treatment fibrosis. The aim this study was to examine effect losartan PQ-intoxicated rats. Adult male Sprague Dawley rats (n = 32, 180-220 g) were randomly assigned four groups: (i) control group; (ii) PQ (iii) + 7d (iv) 14d group. Losartan (intragastrically (i.g.), 10 mg/kg) performed for...
Perfluorinated compounds (PFCs) are a class of emerging pollutants still widely used in different materials as non-adhesives, waterproof fabrics, fire-fighting foams, etc. Their toxic effects include potential for endocrine-disrupting activity, but the amount experimental data available these is limited. The use predictive strategies such quantitative structure–activity relationships (QSARs) recommended under REACH regulation, to fill gaps and screen prioritize chemicals further...
Abstract The Pinatubo eruption in 1991 injected 10–20 Tg SO 2 into the stratosphere, which formed sulfate aerosols through oxidation. Our modeling results show that volcanic heating significantly perturbs heterogeneous and homogeneous chemistry including NO x HO catalytic cycles tropical stratosphere. simulated chemical ozone tendency is positive at 20 mb while negative 10 tropics. of same magnitude as dynamical caused by accelerated upwelling, but with opposite sign. study finds due to...
To investigate the protective effects of betelnut polyphenols on vital organs against high-altitude hypoxia in rats.We compared low-, medium-, and high- dose (400, 800, 1600 mg/kg, respectively) rhodiola Wistar rats. The rats were kept normal condition given drugs daily for 3 days before transfer to a facility at altitude 4010 m, where 5 consecutive hypoxic exposure. then euthanized measuring arterial blood gas assessing liver, lung, brain cardiac pathologies with HE staining. SOD activity,...
The Stratospheric Aerosol and Gas Experiment II (SAGE II) aerosol products are widely used in climatic characteristic studies stratospheric pattern research. Some SAGE products, e.g., temperature, surface area density, 1020 nm extinction coefficient dust storm frequency, from ground-based observations were analysed 1984 to 2005. This analysis explored the time spatial variations of tropospheric aerosols on Tibet Plateau. increased more than two orders magnitude because a large volcanic...