A5034541789- Spectroscopy and Chemometric Analyses
- RNA and protein synthesis mechanisms
- Neurogenesis and neuroplasticity mechanisms
- RNA regulation and disease
- Metabolomics and Mass Spectrometry Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- CRISPR and Genetic Engineering
- Neuroinflammation and Neurodegeneration Mechanisms
- Immune Response and Inflammation
Universitat Autònoma de Barcelona
2023
University of California, Los Angeles
1994
Key events in postnatal brain development, such as neuronal migration, synaptogenesis, and myelination, shape the adult brain. These are reflected changes gray white matter (GM WM) occurring during this period. Therefore, precise knowledge of GM WM composition perinatal development is crucial to characterizing formation well neurodevelopmental disruption observed diseases autism schizophrenia. In study, we combined histochemical immunohistochemical staining with biochemical biophysical...
ABSTRACT Highlights/Main points Astrocyte-targeted IL-6 overproduction during aging increases basal microglial acivation in the facial nucleus. During aging, chronic does not modify response after peripheral nerve injury but T-lymphocyte infiltration. Chronic aged mice motor neuron survival axotomy. Interleukin-6 (IL-6) is main cytokine controlling neuroinflammation and activation increase of levels correlate well with age-related neurodegenerative diseases. Despite relevance these...