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Contact & Profiles
Research Areas
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
Leipzig Heart Institute
2023
Introduction Fibro-calcific aortic valve disease has high prevalence and is associated with significant mortality. Fibrotic extracellular matrix (ECM) remodeling calcific mineral deposition change the valvular microarchitecture deteriorate function. Valvular interstitial cells (VICs) in profibrotic or procalcifying environment are frequently used vitro models. However, processes take several days to weeks develop, even vitro. Continuous monitoring by real-time impedance spectroscopy (EIS)...
10.3389/fcvm.2023.1155371
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Frontiers in Cardiovascular Medicine
2023-06-20
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