A5032029160- Lipid Membrane Structure and Behavior
- Force Microscopy Techniques and Applications
- Laser Material Processing Techniques
- Advanced biosensing and bioanalysis techniques
- Polymer Surface Interaction Studies
- Silk-based biomaterials and applications
- SARS-CoV-2 detection and testing
- Cellular Mechanics and Interactions
- Cell Adhesion Molecules Research
- Ultrasound and Hyperthermia Applications
- Nanopore and Nanochannel Transport Studies
InSysBio (Russia)
2025
Lomonosov Moscow State University
2025
BOKU University
2017-2018
SARS-CoV-2 viral entry requires membrane fusion, which is facilitated by the fusion peptides within its spike protein. These predominantly hydrophobic insert into target membranes; however, their precise mechanistic role in remains incompletely understood. Here, we investigate how FP1 (SFIEDLLFNKVTLADAGFIK), N-terminal peptide, modulates stability and barrier function across various model systems. Through a complementary suite of biophysical techniques—including electrophysiology,...
This study investigates the role of porosity in silicon nanoparticles' ability to act as sonosensitizers for sonodynamic therapy malignant tumors. Structural analysis showed that porous nanoparticles are composed nanocrystals approximately 4 nm size and contain 15 pores, whereas non-porous have a dense structure with ranging from 10 50 nm. Porous exhibit pronounced photoluminescent properties, associated quantum confinement effects their small nanocrystals. The cytotoxicity was investigated...
Mucins, the main component of mucus secretions goblet and epithelial cells, are known for exhibiting a different behaviour in accordance with their surrounding environment (i.e. among others environmental pH), which induces drastic change measured mechanical properties. In this work, we have first employed Atomic Force Microscopy (AFM) Spectroscopy mode to evaluate adhesion porcine mucin films at nanoscale, changes caused particular factor by pH variation between 7.0 4.0, both quite common...
Fibronectin is an extracellular matrix protein that involved in cell adhesion, growth, migration, differentiation, and wound healing. coatings are currently used many laboratories for biomedical biotechnology purposes. In this study we have investigated the adhesion mechanical properties of fibronectin coatings. The were also to role residence time influence loading rate nonspecific interactions. results showed force between silica increased with delivering similar values times 1 2 s....
SARS-CoV-2 viral entry requires membrane fusion, facilitated by fusion peptides within its spike protein. While these predominantly hydrophobic insert into target membranes, their precise mechanistic role in remains incompletely understood. Here, we investigate how FP1, the N-terminal peptide sequence, modulates stability and barrier function across various model systems. Through a complementary suite of biophysical techniques—including electrophysiology, fluorescence spectroscopy,...