Wei Zhu

ORCID: 0009-0006-2060-521X
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About
Contact & Profiles
Research Areas
  • Wheat and Barley Genetics and Pathology
  • Plant Disease Resistance and Genetics
  • Plant Pathogens and Resistance
  • Extraction and Separation Processes
  • Chromosomal and Genetic Variations
  • Yeasts and Rust Fungi Studies
  • Plant Pathogens and Fungal Diseases
  • Genetic Mapping and Diversity in Plants and Animals
  • Human Mobility and Location-Based Analysis
  • Advanced Sensor and Control Systems
  • Physiological and biochemical adaptations
  • Rocket and propulsion systems research
  • Supercapacitor Materials and Fabrication
  • Microwave Engineering and Waveguides
  • Robotics and Sensor-Based Localization
  • Microgrid Control and Optimization
  • Silicon Effects in Agriculture
  • Maritime Transport Emissions and Efficiency
  • Additive Manufacturing and 3D Printing Technologies
  • Plant-based Medicinal Research
  • Geochemistry and Elemental Analysis
  • Antenna Design and Analysis
  • Transportation and Mobility Innovations
  • Grouting, Rheology, and Soil Mechanics
  • Crop Yield and Soil Fertility

Sichuan Agricultural University
2016-2025

Chinese Academy of Sciences
2010-2025

Chengdu Institute of Biology
2024-2025

University of Chinese Academy of Sciences
2025

Zhengzhou University
2024-2025

Huazhong University of Science and Technology
2024-2025

Guangzhou University of Chinese Medicine
2025

Tianjin People's Hospital
2024-2025

Tianjin Medical University
2025

Second Hospital of Tianjin Medical University
2025

Abstract Polyploidization plays a pivotal role in vertebrate evolution and diversification. However, the effects of polyploidization on animals across various biological levels, how these differences drive ecological shifts, remain unclear. Through karyotype analysis whole-genome sequencing, we identified an autotetraploid Microhyla fissipes from Hainan Island, which shows reproductive isolation geographic differentiation its diploid counterpart. Tetraploids exhibited larger cell size,...

10.1093/molbev/msaf037 article EN cc-by Molecular Biology and Evolution 2025-02-06

Diet can influence the thermal performance of ectotherms, providing potential strategies for biological conservation in context global warming. The endangered Andrias davidianus is susceptible to heat stress due energy deficiency liver when fed a worm-based diet rich carbohydrates. A fish-based diet, protein and lipids, improves their performance, but underlying physiological mechanisms remain unclear. In this study, we used metabolomics metagenomics examine combined effects temperature (15,...

10.3389/fmicb.2025.1546912 article EN cc-by Frontiers in Microbiology 2025-03-18

Availability of information on the genetic diversity and population structure germplasm facilitates its use in wheat breeding programs. Recently, with development next-generation sequencing technology, genotyping-by-sequencing (GBS) has been used as a high-throughput cost-effective molecular tool for examination lines. In this study, GBS was to characterize 180 accessions common originating from Asia Europe between latitudes 30° 45°N. total, 24,767 high-quality single-nucleotide polymorphism...

10.3389/fgene.2020.580782 article EN cc-by Frontiers in Genetics 2020-09-25

Abstract Background Combined therapy based on the effects of cascade reactions nanoplatforms to combat specific solid tumor microenvironments is considered a cancer treatment strategy with transformative clinical value. Unfortunately, an insufficient O 2 supply and lack visual indication hinder further applications most for therapy. Results A visualizable nanoplatform liposome nanoparticles loaded GOD, H(Gd), PFP grafted peptide tLyP-1, named tLyP-1 H(Gd)-GOD@PFP, was constructed. The...

10.1186/s12951-023-01765-x article EN cc-by Journal of Nanobiotechnology 2023-01-25

Tetraploid Thinopyrum elongatum, which has superior abiotic stress tolerance characteristics, and exhibits resistance to stripe rust, powdery mildew, Fusarium head blight, is a wild relative of wheat promising source novel genes for improvement. Currently, high-resolution Fluorescence in situ hybridization (FISH) karyotype tetraploid Th. elongatum not available. To develop chromosome-specific FISH-based markers, the hexaploid Trititrigia 8801 two accessions were characterized by different...

10.3389/fpls.2018.00526 article EN cc-by Frontiers in Plant Science 2018-05-01

Stripe rust, which is caused by Puccinia striiformis f. sp. tritici, one of the most devastating foliar diseases common wheat worldwide. Breeding new varieties with durable resistance effective way controlling disease. Tetraploid Thinopyrum elongatum (2n = 4x 28, EEEE) carries a variety genes conferring to multiple diseases, including stripe Fusarium head blight, and powdery mildew, makes it valuable tertiary genetic resource for enhancing cultivar improvement. Here, novel wheat-tetraploid...

10.3390/plants12122311 article EN cc-by Plants 2023-06-14

ABSTRACT Variation patterns in gut microbial diversity among host species and populations offer valuable insights into the mechanisms underlying environment–host–microbiome interactions. However, extent to which phylogeny geography drive these variation animal microbiota remains an open question. Amphibians reptiles are important models address this issue. Using 194 samples of three amphibian four reptile inhabiting Tarim Desert, we demonstrated phylosymbiosis animals, was associated with...

10.1111/1749-4877.12963 article EN cc-by-nc Integrative Zoology 2025-02-10

Fusarium head blight (FHB) is one of the major wheat diseases caused by species (mainly graminearum and asiaticum), resulting in significant global yield losses risks to food security. Breeding varieties with resistance genes most environmentally friendly economical strategy for controlling FHB. Psathyrostachys huashanica Keng ex P. C. Kuo (2n = 2x 14, NsNs), which showed abiotic tolerance biotic resistance, has research value potential as an important genetic resource improvement. In...

10.3390/plants14071104 article EN cc-by Plants 2025-04-02

<title>Abstract</title> <italic>Fusarium</italic> head blight (FHB) is a globally prevalent wheat disease caused by multiple species within <italic>Fusarium</italic>genus. P1142-1-2 wheat-<italic>E. repens</italic> partial amphidiploid with high resistance to FHB. However, its detailed genome composition and the genetic information of chromatin derived from <italic>E. remains unclear, which limits transfer utilization potential gene into wheat. Based on GISH FISH karyotypes analysis, this...

10.21203/rs.3.rs-6308337/v1 preprint EN 2025-04-14

The incidence of diabetes is rising annually, significantly impacting public health and imposing a substantial economic burden on society. Ophiopogonin D (Op D) exhibits certain hypoglycemic effects; however, its mechanisms remain unclear. β-cell dedifferentiation, distinct from apoptosis, pathogenic mechanism we aim to explore regarding Op D's regulatory effects. We established an animal model dedifferentiation assess impact glucose tolerance, blood levels, insulin secretion. employed...

10.3389/fphar.2025.1563201 article EN cc-by Frontiers in Pharmacology 2025-04-29

The Chinese giant salamander (CGS, Andrias davidianus), a flagship amphibian species, is highly vulnerable to high temperatures, posing significant threat under future climate change. Previous research linked this susceptibility liver energy deficiency, accompanied by shifts in gut microbiota and reduced food conversion rates, raising questions about the role of gut-liver axis mediating heat sensitivity. This study investigated responses larvae temperature gradient (10-30 °C), assessing...

10.1186/s12864-025-11644-4 article EN cc-by-nc-nd BMC Genomics 2025-05-13

Fusarium head blight (FHB) caused by the fungus graminearum Schwabe and stripe rust Puccinia striiformis f. sp. tritici are devastating diseases that affect wheat production worldwide. The use of disease-resistant genes cultivars is most effective means reducing fungicide applications to combat these diseases. Elymus repens (2n = 6x 42, StStStStHH) a potentially useful germplasm FHB resistance for improvement.Here, we report development characterization two wheat-E. lines derived from...

10.1186/s12870-019-2208-x article EN cc-by BMC Plant Biology 2019-12-01

Fusarium head blight (FHB), mainly caused by graminearum (Fg), is one of the most devastating fungal diseases in wheat production worldwide. Elymus repens (2n=6x=42, StStStStHH) a wild relative with many biotic and abiotic stress resistance traits. To transfer apply germplasm's gene (s) for breeding, we identified new translocation line K140-7 high to FHB, developed from derivative progenies E. crossed common cultivars. Cytogenetic analyses based on genomic situ hybridization (GISH),...

10.1016/j.jia.2024.03.027 article EN cc-by-nc-nd Journal of Integrative Agriculture 2024-03-01

ABSTRACT The Qingzang Plateau, with its harsh environmental conditions—low oxygen, high ultraviolet radiation and significant temperature fluctuations—demands specialised adaptations for survival. While genetic have been extensively studied, gene expression's role in amphibian adaptation to elevations remains understudied. This study analysed pulmonary expression 119 amphibians across the plateau explore how factors shape evolution. Transcriptomic analyses revealed interspecies variation,...

10.1111/mec.17663 article EN Molecular Ecology 2025-02-03
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