Advances in brain stimulation have made it possible to target smaller and regions for electromagnetic stimulation, the hopes of producing increasingly focal neural effects. However, is extensively interconnected, neurons comprising those connections may themselves be particularly susceptible neurostimulation. Here, we test this hypothesis using single-unit recordings from alert non-human primates receiving transcranial electrical stimulation. We find that putative long-range projections...

Cortical area V4 is thought to be critical for visual object recognition. It contains millimeter-scale domains in which neurons are highly selective stimulus features such as shape, motion, and color. In theory, many different stimuli can decoded from neural activity each of these domains, but whether the brain actually makes use this information unknown. Here we have tested hypothesis, using reversible inactivation non-human primates performing a shape discrimination task. We find that...

Most people easily learn to recognize new faces and places, with more extensive practice they can become experts at visual tasks as complex radiological diagnosis action video games. Such perceptual plasticity has been thoroughly studied in the context of training paradigms that require constant fixation. In contrast, when observers under natural conditions, make frequent saccadic eye movements. Here we show such movements play an important role learning. Observers performed a task which...

Fluctuations in the activity of sensory neurons often predict perceptual decisions. This connection can be quantified with a metric called choice probability (CP), and there is longstanding debate about whether CP reflects causal influence on decisions or an echo decision-making elsewhere brain. Here, we show that reflect third variable, namely, movement used to indicate decision. In standard visual motion discrimination task, middle temporal (MT) area primate cortex responded more strongly...

The primate visual cortex contains various regions that exhibit specialization for different stimulus properties, such as motion, shape, and color. Within each region, there is often further specialization, particular features, horizontal vertical orientations, are over-represented. These asymmetries associated with well-known perceptual biases, but little known about how they influence learning. Most theories would predict learning optimal, in the sense it unaffected by these asymmetries....

Abstract The primate visual cortex contains various regions that exhibit specialization for different stimulus properties, such as motion, shape, and color. Within each region there is often further specialization, particular features, horizontal vertical orientations, are overrepresented. These asymmetries associated with well-known perceptual biases, but little known about how they influence learning. Most theories would predict learning optimal, in the sense it unaffected by these...

Abstract Fluctuations in the activity of sensory neurons often predict perceptual decisions. This connection can be quantified with a metric called choice probability (CP), and there has been longstanding debate about whether CP reflects causal influence on decisions, or an echo decision-making elsewhere brain. Here we show that actually reflect third variable, namely movement used to indicate decision. In standard visual motion discrimination task, middle temporal (MT) area primate cortex...