- Glycosylation and Glycoproteins Research
- Plant responses to water stress
- Heme Oxygenase-1 and Carbon Monoxide
- Cancer-related molecular mechanisms research
- Mitochondrial Function and Pathology
- Paraquat toxicity studies and treatments
- Cytomegalovirus and herpesvirus research
- Gastrointestinal disorders and treatments
- Gastrointestinal motility and disorders
- interferon and immune responses
- Alzheimer's disease research and treatments
- Animal health and immunology
- Pancreatic function and diabetes
China Agricultural University
2024
Xijing Hospital
2013-2021
Air Force Medical University
2013-2021
To evaluate the efficacy of combined treatment with bone marrow mesenchymal stem cell (BMSC) transplantation and methylprednisolone (MP) to treat paraquat (PQ)-induced acute lung injury. A total 102 female rats were randomly divided into five groups: PQ, BMSC, MP, BMSC + MP normal control. After 14 days PQ poisoning, survival rats, wet/dry weight ratio tissue, serum levels tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, IL-10, malondialdehyde (MDA) superoxidase dismutase (SOD),...
Alzheimer's disease (AD) and ischemic brain injury are two major neurodegenerative diseases. Mitochondrial dysfunction commonly occurs in AD injury. Currently, little attention has been paid to the glycans on mitochondrial glycoproteins, which may play vital roles during process of dysfunction. The aim this study was illustrate compare glycopattern alterations glycoproteins extracted from cerebral cortex rat models these diseases using High-throughput lectin microarrays. results shown that...
Chicken yolk immunoglobulin (IgY) is a natural immunologically active antibody extracted from egg and can be used as dietary supplement for the treatment of inflammation damage to intestines. In our study, IgY was embedded in double emulsion (W/O/W; DE) explore therapeutic effect on Lipopolysaccharide (LPS)-induced jejunal injury mice. The results showed that W/O/W-embedded (IgY + attenuated LPS-induced mouse small intestinal structures protected integrity mucosal barrier. DE increased...