A5058451905- Multiple Sclerosis Research Studies
- Substance Abuse Treatment and Outcomes
- Alcohol Consumption and Health Effects
- Polyomavirus and related diseases
- Rheumatoid Arthritis Research and Therapies
- Homelessness and Social Issues
- Child Abuse and Trauma
- Mental Health Treatment and Access
- Acute Lymphoblastic Leukemia research
- Healthcare Policy and Management
- Child and Adolescent Psychosocial and Emotional Development
- Opioid Use Disorder Treatment
- Systemic Sclerosis and Related Diseases
- Suicide and Self-Harm Studies
- Infant Development and Preterm Care
- Geriatric Care and Nursing Homes
- Health Systems, Economic Evaluations, Quality of Life
- Health disparities and outcomes
- Maternal Mental Health During Pregnancy and Postpartum
- Peripheral Neuropathies and Disorders
- Child Welfare and Adoption
- Bone health and osteoporosis research
- Nutritional Studies and Diet
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Musculoskeletal pain and rehabilitation
Manitoba Health
2016-2025
University of Manitoba
2016-2025
University of Saskatchewan
2022-2024
Nova Scotia Health Authority
2022-2024
Dalhousie University
2022-2024
Flinders University
2024
SA Health
2024
Saskatchewan Health Quality Council
2022-2024
University of British Columbia
2022
University College London
2022
The health effects of a binge pattern alcohol consumption have not been widely investigated. objective this study was to evaluate the cardiovascular consequences drinking (consumption eight or more drinks at one sitting) and usual (nonbinge) in longitudinal, population-based study. Data obtained from 1,154 men women aged 18–64 years interviewed Winnipeg, Manitoba, Canada, 1990 1991 were linked care utilization mortality records. Using an 8-year follow-up period, authors performed separate...
Background: The multiple sclerosis (MS) prodrome is poorly characterized. Objective: To phenotype the MS via health care encounters. Methods: Using data from a population-based cohort study linking administrative and clinical in four Canadian provinces, we compared physician hospital encounters prescriptions filled (via International Classification of Diseases chapters, specialty or drug classes) for subjects 5 years before first demyelinating claim an symptom onset clinic-derived cohort, to...
It is not possible to fully establish the safety of a disease-modifying drug (DMD) for multiple sclerosis (MS) from randomized controlled trials as only very common adverse events occurring over short-term can be captured, and quality reporting has been variable. We examined relationship between DMDs MS potential in multiregion population-based study.
<h3>Objective</h3> To determine whether cancer risk differs in people with and without multiple sclerosis (MS), we compared incidence rates cancer-specific mortality MS matched cohorts using population-based data sources. <h3>Methods</h3> We conducted a retrospective cohort study administrative from Manitoba Ontario, Canada. applied validated case definition to identify cases, then selected 5 controls on birth year, sex, region. linked these registries, estimated of breast, colorectal, 13...
Objective: To compare the rate of mental disorders (i.e., mood and anxiety, substance use, psychotic disorders) suicide attempts within same group women across pre-pregnancy, pregnancy, postpartum periods, between this perinatal cohort a non-perinatal reference group. Method: Data were from an administrative repository residents in Manitoba, Canada. The consisted aged 18 to 45 years who experienced >1 live birth pregnancy 2011 2014 ( n = 45,362). Pre-pregnancy, periods defined over...
Objective Many individuals exposed to SARS-CoV-2 experience long-term symptoms as part of a syndrome called post-COVID condition (PCC). Research on PCC is still emerging but urgently needed support diagnosis, clinical treatment guidelines and health system resource allocation. In this study, we developed method identify cases using administrative data report prevalence predictive factors in Manitoba, Canada. Design Cohort study. Setting Participants All Manitobans who tested positive for...
To compare measures of bone mineral density (BMD) between people with and without MS.Using population-based administrative data from Manitoba, Canada, we identified MS who received BMD screening controls matched 5:1 on age, sex, region residence, date screening. We determined the T-scores for femoral neck, total hip, lumbar spine frequency osteoporosis (defined as T-score -2.5 or lower). compared groups respect to neck using multivariable linear regression, adjusting region, disability,...
Issues around end-of-life health care have attracted increasing attention in the last decade. One question that has arisen is whether very elderly individuals receive overly aggressive treatment at end of life. The purpose this study was to address issue by examining use life varies age.The included all adults 65 years old or older who died Manitoba, Canada 2000 (N = 7678). Measures were derived from administrative data files and location death, hospitalizations, intensive unit (ICU)...
Background: research has reliably demonstrated cardioprotection from regular alcohol use. Heavy episodic drinking (HED), however, negates these beneficial effects and increases the risk of cardiovascular disease (CVD). The impact age on health not been evaluated.
ABSTRACT People with multiple sclerosis (MS) have a higher risk of low bone mineral density (BMD), osteoporosis, and osteoporotic fractures than healthy adults. The Fracture Risk Assessment tool (FRAX®) has been reported to underestimate fracture in people MS when BMD is unknown. We tested FRAX performance for known, determined if factor independent score. Using population-based databases Manitoba, Canada, we identified who underwent screening after diagnosis (n = 744) controls matched on...
We examined the association between disease-modifying drugs (DMDs) for multiple sclerosis (MS) and survival in a multiregion population-based study.We accessed administrative health databases from 4 Canadian provinces. Persons with MS were identified followed most recent of first or demyelinating event January 1, 1996 (index date), until death, emigration, December 31, 2017. Association first-generation second-generation DMDs all-cause mortality was using stratified Cox proportional hazard...
To examine the association between maternal depression and anxiety disorders (MDAD) child development assessed during kindergarten year.Administrative data from several health social databases in Manitoba, Canada, were used to study 18,331 mother-child pairs. MDAD over period one year prior child's birth was defined using physician diagnoses filled prescriptions. Child Early Development Instrument (EDI) which measures vulnerability across five domains of development. Structural equation...
High-risk alcohol consumption is associated with compromised health. This study aimed to compare the incidence of alcohol-related cancers, diabetes, ischemic heart disease (IHD) and mortality between those without an indication use disorder (AUD).Retrospective, population-based, matched cohort using data from Manitoba Population Research Data Repository. Rates were modeled generalized linear models either negative binomial distribution or Poisson a log offset person-years account for each...
Objectives: To determine the prevalence of mental illness in older adults and its effect on home care personal (PCH) use. Methods: Using nonidentifying administrative records (fiscal years 1997–1998 to 2001–2002) from Population Health Research Data Repository housed at Manitoba Centre for Policy, we determined 5-year period individuals aged 55 over (119 539 men 145 752 women) 3 categories: cumulative disorders (those having a diagnosis depression, anxiety disorder, personality...
INTRODUCTION: Changing socio-economic gradients in adult health over time have been documented, but little research has investigated temporal changes child gradients. Childhood hospitalizations for injury fallen the last two decades; whether gradient childhood changed is unknown. METHODS: Population-based hospital discharge data were used to calculate rates of hospitalization from 1986/87 through 2005/06 all children under 20 years age Manitoba (average yearly number = 326,357). Information...
Background Few studies have explored predictors of early childhood anxiety. Objective To determine the prenatal, postnatal, and life anxiety by age 5. Methods Population-based, provincial administrative data (N = 19,316) from Manitoba, Canada were used to association between demographic, obstetrical, psychosocial, medical, behavioral, infant factors on Results Risk for 5 included maternal psychological distress birth 12 months 13 years post-delivery an 5-minute Apgar score ≤7. Factors...
Objective The life course of children and adolescents with mental disorders is an important area investigation, yet it remains understudied. This study provides a first-ever comprehensive examination the relationship between child adolescent subsequent suicidal adverse social outcomes in early adulthood using population-based data. Methods De-identified administrative databases were used to create birth cohort 60,838 residents Manitoba born April 1980 March 1985 who followed until 2015....