A5092097338- SARS-CoV-2 detection and testing
- Biosensors and Analytical Detection
- Molecular Biology Techniques and Applications
- SARS-CoV-2 and COVID-19 Research
Polymerase chain reaction (PCR)-based assays were widely deployed during the SARS-CoV-2 pandemic for population-scale testing. High-throughput molecular diagnostic laboratories required a high degree of process automation to cope with huge testing demands, fast turnaround times, and quality requirements. However, developers optimizers often neglected critical step preparing PCR Master Mix. The construction Mix depends on operator skill manual pipetting reagents. Manual procedures introduce...
Abstract In late 2021, the Omicron SARS-CoV-2 variant spread rapidly worldwide. To track its emergence, and continued evolution of while giving actionable epidemiological data that informs public health policy, we developed a high-throughput, automated, genotyping workflow pairs flexible liquid handling with re-configurable LIMS system. This facilitated real-time monitoring BA.4 BA.5, by time retirement, system was responsible for typing c . 400,000 samples. When combined population-scale...
Abstract Polymerase Chain Reaction (PCR)-based assays were widely deployed during the SARS-CoV-2 pandemic for population-scale testing. High-throughput molecular diagnostic labora-tories required a high degree of process automation to cope with huge testing demand, fast turn-around times and quality requirements. However, critical step preparing PCR MasterMix has often been neglected by developers optimisers, is largely dependent upon operator skill manual pipetting reagents construct...