A5103094101- ECG Monitoring and Analysis
- Brain Tumor Detection and Classification
- Peptidase Inhibition and Analysis
- Non-Invasive Vital Sign Monitoring
- Advanced Computing and Algorithms
- Ubiquitin and proteasome pathways
- EEG and Brain-Computer Interfaces
- Organic Light-Emitting Diodes Research
- Organic Electronics and Photovoltaics
- Protein Degradation and Inhibitors
- Glycosylation and Glycoproteins Research
- RNA regulation and disease
- Conducting polymers and applications
- Phonocardiography and Auscultation Techniques
- Endoplasmic Reticulum Stress and Disease
- Autophagy in Disease and Therapy
- Image and Signal Denoising Methods
Shandong University
2024
Shanghai Jiao Tong University
2024
South China University of Technology
2007
In recent years, there has been a surge in applying deep learning methods for signal quality assessment (SQA) and denoising of ECG signals. However, solely focusing on can lead to situations where models trained severely contaminated signals perform poorly higher-quality Likewise, carrying out SQA isolation may be constrained by the number training data susceptible label noise. this study, we leverage correlation between propose multi-task network (MTL-NET) that addresses both tasks parallel...
Abstract: Motion interference is a major issue in the process of acquiring electrocardiogram (ECG) signals. It introduces noise and artifacts into ECG signal, causing signal distortion deformation, thus affecting accuracy subsequent analyses diagnoses. This study deep learning-based model for motion artifact removal signals, namely MSCT, which combines Multi-Scale Convolution with Transformer encoder to extract local global features signals artifacts. The comparative experiments are...
Ubiquitination is a cascade reaction involving E1, E2, and E3 enzymes. The orthogonal ubiquitin transfer (OUT) method has been previously established to identify potential substrates of ligases. In this study, we verified the ubiquitination five mediated by ligases CHIP E4B. To further explore activity U‐box domains ligases, two mutants with interchanged between E4B were generated. They exhibited significantly reduced ability. Additionally, different E3s recruited similar E2...
The PERK-eIF2α pathway plays an essential role in endoplasmic reticulum (ER) stress. When the is activated, PERK phosphorylates eIF2α (p-eIF2α) at Ser51 and quenches global protein synthesis. In this study, we verified as a bona fide substrate of E3 ubiquitin ligase CHIP both vitro cells. mediated ubiquitination degradation nonphosphorylated chaperone-independent manner promoted upregulation transcription factor ATF4 under ER stress conditions. induced transcriptional enhancement tumor...