A5003093161- Peroxisome Proliferator-Activated Receptors
- Agricultural Science and Fertilization
- RNA modifications and cancer
- Microbial Metabolic Engineering and Bioproduction
- Cancer-related gene regulation
- RNA Research and Splicing
University of Groningen
2024-2025
Peroxisomes are organelles that crucial for cellular metabolism, but they also play important roles in non-metabolic processes such as signalling, stress response or antiviral defense. To uncover the consequences of peroxisome deficiency, we compared Saccharomyces cerevisiae wild-type with pex3 cells, which lack peroxisomes, employing quantitative proteomics and transcriptomics technologies. Cells were grown on acetate, a carbon source requires peroxisomal enzymes glyoxylate cycle to...
Abstract Peroxisomes are organelles that crucial for cellular metabolism. However, these play also important roles in non-metabolic processes, such as signalling. To uncover the consequences of peroxisome deficiency, we compared two extremes, namely Saccharomyces cerevisiae wild-type and pex3 cells, which lack functional peroxisomes, employing transcriptomics quantitative proteomics technology. Cells were grown on acetate, a carbon source involves peroxisomal enzymes glyoxylate cycle does...